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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IFIT3
Full Name:
Interferon-induced protein with tetratricopeptide repeats 3
Alias:
CIG-49; GARG-49; IFI60; IFIT-3; IFIT4; IFIT-4; IRG2; ISG60; RIG-G
Type:
Unknown function
Mass (Da):
55985
Number AA:
490
UniProt ID:
O14879
International Prot ID:
IPI00024254
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
E
V
T
K
N
S
L
E
K
I
L
P
Q
Site 2
S29
W
N
L
F
K
E
D
S
V
S
R
D
L
E
D
Site 3
S31
L
F
K
E
D
S
V
S
R
D
L
E
D
R
V
Site 4
T47
N
Q
I
E
F
L
N
T
E
F
K
A
T
M
Y
Site 5
Y54
T
E
F
K
A
T
M
Y
N
L
L
A
Y
I
K
Site 6
Y59
T
M
Y
N
L
L
A
Y
I
K
H
L
D
G
N
Site 7
Y104
W
G
N
Y
A
W
V
Y
Y
H
L
G
R
L
S
Site 8
Y105
G
N
Y
A
W
V
Y
Y
H
L
G
R
L
S
D
Site 9
S111
Y
Y
H
L
G
R
L
S
D
A
Q
I
Y
V
D
Site 10
Y116
R
L
S
D
A
Q
I
Y
V
D
K
V
K
Q
T
Site 11
S132
K
K
F
S
N
P
Y
S
I
E
Y
S
E
L
D
Site 12
Y135
S
N
P
Y
S
I
E
Y
S
E
L
D
C
E
E
Site 13
S136
N
P
Y
S
I
E
Y
S
E
L
D
C
E
E
G
Site 14
Y181
S
G
L
A
I
A
M
Y
H
L
D
N
H
P
E
Site 15
S192
N
H
P
E
K
Q
F
S
T
D
V
L
K
Q
A
Site 16
T193
H
P
E
K
Q
F
S
T
D
V
L
K
Q
A
I
Site 17
S203
L
K
Q
A
I
E
L
S
P
D
N
Q
Y
V
K
Site 18
Y208
E
L
S
P
D
N
Q
Y
V
K
V
L
L
G
L
Site 19
S237
V
E
E
A
L
E
K
S
P
C
Q
T
D
V
L
Site 20
T241
L
E
K
S
P
C
Q
T
D
V
L
R
S
A
A
Site 21
Y251
L
R
S
A
A
K
F
Y
R
R
K
G
D
L
D
Site 22
S270
L
F
Q
R
V
L
E
S
T
P
N
N
G
Y
L
Site 23
T271
F
Q
R
V
L
E
S
T
P
N
N
G
Y
L
Y
Site 24
Y276
E
S
T
P
N
N
G
Y
L
Y
H
Q
I
G
C
Site 25
Y285
Y
H
Q
I
G
C
C
Y
K
A
K
V
R
Q
M
Site 26
T295
K
V
R
Q
M
Q
N
T
G
E
S
E
A
S
G
Site 27
S301
N
T
G
E
S
E
A
S
G
N
K
E
M
I
E
Site 28
Y313
M
I
E
A
L
K
Q
Y
A
M
D
Y
S
N
K
Site 29
Y317
L
K
Q
Y
A
M
D
Y
S
N
K
A
L
E
K
Site 30
T341
D
L
A
E
F
L
E
T
E
C
Y
Q
T
P
F
Site 31
Y344
E
F
L
E
T
E
C
Y
Q
T
P
F
N
K
E
Site 32
T346
L
E
T
E
C
Y
Q
T
P
F
N
K
E
V
P
Site 33
Y364
K
Q
Q
S
H
Q
R
Y
C
N
L
Q
K
Y
N
Site 34
Y370
R
Y
C
N
L
Q
K
Y
N
G
K
S
E
D
T
Site 35
S374
L
Q
K
Y
N
G
K
S
E
D
T
A
V
Q
H
Site 36
S387
Q
H
G
L
E
G
L
S
I
S
K
K
S
T
D
Site 37
S392
G
L
S
I
S
K
K
S
T
D
K
E
E
I
K
Site 38
T393
L
S
I
S
K
K
S
T
D
K
E
E
I
K
D
Site 39
Y417
L
P
Q
N
A
P
N
Y
W
Y
L
Q
G
L
I
Site 40
Y419
Q
N
A
P
N
Y
W
Y
L
Q
G
L
I
H
K
Site 41
S461
G
S
I
F
L
S
A
S
E
L
E
D
G
S
E
Site 42
S467
A
S
E
L
E
D
G
S
E
E
M
G
Q
G
A
Site 43
S477
M
G
Q
G
A
V
S
S
S
P
R
E
L
L
S
Site 44
S478
G
Q
G
A
V
S
S
S
P
R
E
L
L
S
N
Site 45
S484
S
S
P
R
E
L
L
S
N
S
E
Q
L
N
_
Site 46
S486
P
R
E
L
L
S
N
S
E
Q
L
N
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation