KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ApoL1
Full Name:
Apolipoprotein L1
Alias:
APOL; Apo-L; ApoL-I; Apolipoprotein L; Apolipoprotein L, 1; Apolipoprotein L-I; Apolipoprotein-L1 precursor
Type:
Channel, chloride; Lipid binding protein
Mass (Da):
43974
Number AA:
398
UniProt ID:
O14791
International Prot ID:
Isoform1 - IPI00514475
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0034364
GO:0031224
GO:0034361
Uniprot
OncoNet
Molecular Function:
GO:0005254
GO:0008289
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006821
GO:0008203
GO:0019835
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T44
N
V
P
S
G
T
D
T
G
D
P
Q
S
K
P
Site 2
S49
T
D
T
G
D
P
Q
S
K
P
L
G
D
W
A
Site 3
T59
L
G
D
W
A
A
G
T
M
D
P
E
S
S
I
Site 4
S64
A
G
T
M
D
P
E
S
S
I
F
I
E
D
A
Site 5
Y74
F
I
E
D
A
I
K
Y
F
K
E
K
V
S
T
Site 6
T89
Q
N
L
L
L
L
L
T
D
N
E
A
W
N
G
Site 7
S149
K
E
F
P
R
L
K
S
E
L
E
D
N
I
R
Site 8
S225
A
A
L
T
G
I
T
S
S
T
M
D
Y
G
K
Site 9
S226
A
L
T
G
I
T
S
S
T
M
D
Y
G
K
K
Site 10
Y230
I
T
S
S
T
M
D
Y
G
K
K
W
W
T
Q
Site 11
S247
A
H
D
L
V
I
K
S
L
D
K
L
K
E
V
Site 12
S267
E
N
I
S
N
F
L
S
L
A
G
N
T
Y
Q
Site 13
S295
R
A
R
A
N
L
Q
S
V
P
H
A
S
A
S
Site 14
S300
L
Q
S
V
P
H
A
S
A
S
R
P
R
V
T
Site 15
S302
S
V
P
H
A
S
A
S
R
P
R
V
T
E
P
Site 16
T307
S
A
S
R
P
R
V
T
E
P
I
S
A
E
S
Site 17
S311
P
R
V
T
E
P
I
S
A
E
S
G
E
Q
V
Site 18
S314
T
E
P
I
S
A
E
S
G
E
Q
V
E
R
V
Site 19
S325
V
E
R
V
N
E
P
S
I
L
E
M
S
R
G
Site 20
Y354
L
D
V
V
Y
L
V
Y
E
S
K
H
L
H
E
Site 21
S365
H
L
H
E
G
A
K
S
E
T
A
E
E
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation