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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNB5
Full Name:
Guanine nucleotide-binding protein subunit beta-5
Alias:
Gbeta5;Transducin beta chain 5
Type:
Mass (Da):
43566
Number AA:
395
UniProt ID:
O14775
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
L
R
P
V
F
K
K
S
Q
Q
L
S
Y
C
S
Site 2
S34
F
K
K
S
Q
Q
L
S
Y
C
S
T
C
A
E
Site 3
T45
T
C
A
E
I
M
A
T
E
G
L
H
E
N
E
Site 4
T53
E
G
L
H
E
N
E
T
L
A
S
L
K
S
E
Site 5
S56
H
E
N
E
T
L
A
S
L
K
S
E
A
E
S
Site 6
S59
E
T
L
A
S
L
K
S
E
A
E
S
L
K
G
Site 7
S63
S
L
K
S
E
A
E
S
L
K
G
K
L
E
E
Site 8
T97
L
G
Q
F
V
M
K
T
R
R
T
L
K
G
H
Site 9
T100
F
V
M
K
T
R
R
T
L
K
G
H
G
N
K
Site 10
S122
K
D
K
R
R
I
V
S
S
S
Q
D
G
K
V
Site 11
S123
D
K
R
R
I
V
S
S
S
Q
D
G
K
V
I
Site 12
S124
K
R
R
I
V
S
S
S
Q
D
G
K
V
I
V
Site 13
T136
V
I
V
W
D
S
F
T
T
N
K
E
H
A
V
Site 14
S172
G
G
L
D
N
K
C
S
V
Y
P
L
T
F
D
Site 15
Y174
L
D
N
K
C
S
V
Y
P
L
T
F
D
K
N
Site 16
T177
K
C
S
V
Y
P
L
T
F
D
K
N
E
N
M
Site 17
T195
K
K
S
V
A
M
H
T
N
Y
L
S
A
C
S
Site 18
S202
T
N
Y
L
S
A
C
S
F
T
N
S
D
M
Q
Site 19
T212
N
S
D
M
Q
I
L
T
A
S
G
D
G
T
C
Site 20
S232
E
S
G
Q
L
L
Q
S
F
H
G
H
G
A
D
Site 21
T253
A
P
S
E
T
G
N
T
F
V
S
G
G
C
D
Site 22
S282
Q
A
F
E
T
H
E
S
D
I
N
S
V
R
Y
Site 23
S286
T
H
E
S
D
I
N
S
V
R
Y
Y
P
S
G
Site 24
Y289
S
D
I
N
S
V
R
Y
Y
P
S
G
D
A
F
Site 25
Y290
D
I
N
S
V
R
Y
Y
P
S
G
D
A
F
A
Site 26
S292
N
S
V
R
Y
Y
P
S
G
D
A
F
A
S
G
Site 27
S298
P
S
G
D
A
F
A
S
G
S
D
D
A
T
C
Site 28
S300
G
D
A
F
A
S
G
S
D
D
A
T
C
R
L
Site 29
T304
A
S
G
S
D
D
A
T
C
R
L
Y
D
L
R
Site 30
Y308
D
D
A
T
C
R
L
Y
D
L
R
A
D
R
E
Site 31
S320
D
R
E
V
A
I
Y
S
K
E
S
I
I
F
G
Site 32
S371
F
G
H
E
N
R
V
S
T
L
R
V
S
P
D
Site 33
T372
G
H
E
N
R
V
S
T
L
R
V
S
P
D
G
Site 34
S376
R
V
S
T
L
R
V
S
P
D
G
T
A
F
C
Site 35
T380
L
R
V
S
P
D
G
T
A
F
C
S
G
S
W
Site 36
S384
P
D
G
T
A
F
C
S
G
S
W
D
H
T
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation