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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDX4
Full Name:
Homeobox protein CDX-4
Alias:
Caudal-type homeobox protein 4
Type:
Mass (Da):
30480
Number AA:
284
UniProt ID:
O14627
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
L
E
K
E
A
G
M
Y
P
G
T
L
M
S
P
Site 2
T17
E
A
G
M
Y
P
G
T
L
M
S
P
G
G
D
Site 3
S20
M
Y
P
G
T
L
M
S
P
G
G
D
G
T
A
Site 4
T26
M
S
P
G
G
D
G
T
A
G
T
G
G
T
G
Site 5
T29
G
G
D
G
T
A
G
T
G
G
T
G
G
G
G
Site 6
S37
G
G
T
G
G
G
G
S
P
M
P
A
S
N
F
Site 7
S68
S
M
D
P
H
W
P
S
L
G
V
W
G
S
P
Site 8
S74
P
S
L
G
V
W
G
S
P
Y
S
P
P
R
E
Site 9
Y76
L
G
V
W
G
S
P
Y
S
P
P
R
E
D
W
Site 10
S77
G
V
W
G
S
P
Y
S
P
P
R
E
D
W
S
Site 11
S84
S
P
P
R
E
D
W
S
V
Y
P
G
P
S
S
Site 12
Y86
P
R
E
D
W
S
V
Y
P
G
P
S
S
T
M
Site 13
T95
G
P
S
S
T
M
G
T
V
P
V
N
D
V
T
Site 14
S110
S
S
P
A
A
F
C
S
T
D
Y
S
N
L
G
Site 15
T111
S
P
A
A
F
C
S
T
D
Y
S
N
L
G
P
Site 16
S114
A
F
C
S
T
D
Y
S
N
L
G
P
V
G
G
Site 17
S124
G
P
V
G
G
G
T
S
G
S
S
L
P
G
Q
Site 18
S126
V
G
G
G
T
S
G
S
S
L
P
G
Q
A
G
Site 19
S127
G
G
G
T
S
G
S
S
L
P
G
Q
A
G
G
Site 20
S148
A
G
A
A
K
A
S
S
P
S
R
S
R
H
S
Site 21
S150
A
A
K
A
S
S
P
S
R
S
R
H
S
P
Y
Site 22
S152
K
A
S
S
P
S
R
S
R
H
S
P
Y
A
W
Site 23
S155
S
P
S
R
S
R
H
S
P
Y
A
W
M
R
K
Site 24
Y157
S
R
S
R
H
S
P
Y
A
W
M
R
K
T
V
Site 25
T163
P
Y
A
W
M
R
K
T
V
Q
V
T
G
K
T
Site 26
Y176
K
T
R
T
K
E
K
Y
R
V
V
Y
T
D
H
Site 27
Y180
K
E
K
Y
R
V
V
Y
T
D
H
Q
R
L
E
Site 28
T199
F
H
C
N
R
Y
I
T
I
Q
R
K
S
E
L
Site 29
S204
Y
I
T
I
Q
R
K
S
E
L
A
V
N
L
G
Site 30
S237
K
M
I
K
K
K
I
S
Q
F
E
N
S
G
G
Site 31
S242
K
I
S
Q
F
E
N
S
G
G
S
V
Q
S
D
Site 32
S245
Q
F
E
N
S
G
G
S
V
Q
S
D
S
D
S
Site 33
S248
N
S
G
G
S
V
Q
S
D
S
D
S
I
S
P
Site 34
S250
G
G
S
V
Q
S
D
S
D
S
I
S
P
G
E
Site 35
S252
S
V
Q
S
D
S
D
S
I
S
P
G
E
L
P
Site 36
S254
Q
S
D
S
D
S
I
S
P
G
E
L
P
N
T
Site 37
T261
S
P
G
E
L
P
N
T
F
F
T
T
P
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation