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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UTY
Full Name:
Histone demethylase UTY
Alias:
Ubiquitously transcribed Y chromosome tetratricopeptide repeat
Type:
Nucleus protein
Mass (Da):
149548
Number AA:
1347
UniProt ID:
O14607
International Prot ID:
IPI00023013
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0005506
GO:0016702
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
K
M
A
E
G
K
A
S
R
E
S
E
E
E
S
Site 2
S31
E
G
K
A
S
R
E
S
E
E
E
S
V
S
L
Site 3
S35
S
R
E
S
E
E
E
S
V
S
L
T
V
E
E
Site 4
S37
E
S
E
E
E
S
V
S
L
T
V
E
E
R
E
Site 5
T39
E
E
E
S
V
S
L
T
V
E
E
R
E
A
L
Site 6
T68
E
D
G
A
R
T
K
T
L
L
G
K
A
V
R
Site 7
S90
K
A
E
G
K
V
E
S
D
F
F
C
Q
L
G
Site 8
S107
N
L
L
L
E
D
Y
S
K
A
L
S
A
Y
Q
Site 9
S111
E
D
Y
S
K
A
L
S
A
Y
Q
R
Y
Y
S
Site 10
Y113
Y
S
K
A
L
S
A
Y
Q
R
Y
Y
S
L
Q
Site 11
Y117
L
S
A
Y
Q
R
Y
Y
S
L
Q
A
D
Y
W
Site 12
Y123
Y
Y
S
L
Q
A
D
Y
W
K
N
A
A
F
L
Site 13
Y155
K
A
F
Q
D
V
L
Y
V
D
P
S
F
C
R
Site 14
S159
D
V
L
Y
V
D
P
S
F
C
R
A
K
E
I
Site 15
T178
G
L
M
F
K
V
N
T
D
Y
K
S
S
L
K
Site 16
Y180
M
F
K
V
N
T
D
Y
K
S
S
L
K
H
F
Site 17
S182
K
V
N
T
D
Y
K
S
S
L
K
H
F
Q
L
Site 18
Y212
Q
F
H
I
A
H
L
Y
E
T
Q
R
K
Y
H
Site 19
T214
H
I
A
H
L
Y
E
T
Q
R
K
Y
H
S
A
Site 20
Y218
L
Y
E
T
Q
R
K
Y
H
S
A
K
E
A
Y
Site 21
Y269
K
E
S
Y
A
I
Q
Y
L
Q
K
S
L
E
A
Site 22
S273
A
I
Q
Y
L
Q
K
S
L
E
A
D
P
N
S
Site 23
S280
S
L
E
A
D
P
N
S
G
Q
S
W
Y
F
L
Site 24
Y285
P
N
S
G
Q
S
W
Y
F
L
G
R
C
Y
S
Site 25
Y291
W
Y
F
L
G
R
C
Y
S
S
I
G
K
V
Q
Site 26
S292
Y
F
L
G
R
C
Y
S
S
I
G
K
V
Q
D
Site 27
S303
K
V
Q
D
A
F
I
S
Y
R
Q
S
I
D
K
Site 28
S307
A
F
I
S
Y
R
Q
S
I
D
K
S
E
A
S
Site 29
S311
Y
R
Q
S
I
D
K
S
E
A
S
A
D
T
W
Site 30
S314
S
I
D
K
S
E
A
S
A
D
T
W
C
S
I
Site 31
Y359
W
M
D
L
G
T
L
Y
E
S
C
N
Q
P
Q
Site 32
Y372
P
Q
D
A
I
K
C
Y
L
N
A
A
R
S
K
Site 33
S378
C
Y
L
N
A
A
R
S
K
R
C
S
N
T
S
Site 34
S382
A
A
R
S
K
R
C
S
N
T
S
T
L
A
A
Site 35
S385
S
K
R
C
S
N
T
S
T
L
A
A
R
I
K
Site 36
T386
K
R
C
S
N
T
S
T
L
A
A
R
I
K
F
Site 37
S417
H
P
V
Q
Q
V
Y
S
L
C
L
T
P
Q
K
Site 38
T421
Q
V
Y
S
L
C
L
T
P
Q
K
L
Q
H
L
Site 39
S451
H
Q
L
E
Q
L
E
S
Q
F
V
L
M
Q
Q
Site 40
T478
G
I
H
N
G
A
I
T
D
S
S
L
P
T
N
Site 41
S480
H
N
G
A
I
T
D
S
S
L
P
T
N
S
V
Site 42
S481
N
G
A
I
T
D
S
S
L
P
T
N
S
V
S
Site 43
T484
I
T
D
S
S
L
P
T
N
S
V
S
N
R
Q
Site 44
S486
D
S
S
L
P
T
N
S
V
S
N
R
Q
P
H
Site 45
S488
S
L
P
T
N
S
V
S
N
R
Q
P
H
G
A
Site 46
T497
R
Q
P
H
G
A
L
T
R
V
S
S
V
S
Q
Site 47
S500
H
G
A
L
T
R
V
S
S
V
S
Q
P
G
V
Site 48
S501
G
A
L
T
R
V
S
S
V
S
Q
P
G
V
R
Site 49
S503
L
T
R
V
S
S
V
S
Q
P
G
V
R
P
A
Site 50
S550
G
S
N
C
I
A
G
S
E
S
N
G
N
V
P
Site 51
Y558
E
S
N
G
N
V
P
Y
L
Q
Q
N
T
H
T
Site 52
T571
H
T
L
P
H
N
H
T
D
L
N
S
S
T
E
Site 53
T577
H
T
D
L
N
S
S
T
E
E
P
W
R
K
Q
Site 54
S586
E
P
W
R
K
Q
L
S
N
S
A
Q
G
L
H
Site 55
S595
S
A
Q
G
L
H
K
S
Q
S
S
C
L
S
G
Site 56
S597
Q
G
L
H
K
S
Q
S
S
C
L
S
G
P
N
Site 57
S598
G
L
H
K
S
Q
S
S
C
L
S
G
P
N
E
Site 58
S601
K
S
Q
S
S
C
L
S
G
P
N
E
E
Q
P
Site 59
S614
Q
P
L
F
S
T
G
S
A
Q
Y
H
Q
A
T
Site 60
T633
K
K
A
N
E
H
L
T
L
P
S
N
S
V
P
Site 61
S636
N
E
H
L
T
L
P
S
N
S
V
P
Q
G
D
Site 62
S638
H
L
T
L
P
S
N
S
V
P
Q
G
D
A
D
Site 63
S646
V
P
Q
G
D
A
D
S
H
L
S
C
H
T
A
Site 64
S649
G
D
A
D
S
H
L
S
C
H
T
A
T
S
G
Site 65
S655
L
S
C
H
T
A
T
S
G
G
Q
Q
G
I
M
Site 66
T664
G
Q
Q
G
I
M
F
T
K
E
S
K
P
S
K
Site 67
S667
G
I
M
F
T
K
E
S
K
P
S
K
N
R
S
Site 68
S670
F
T
K
E
S
K
P
S
K
N
R
S
L
V
P
Site 69
S674
S
K
P
S
K
N
R
S
L
V
P
E
T
S
R
Site 70
T679
N
R
S
L
V
P
E
T
S
R
H
T
G
D
T
Site 71
S680
R
S
L
V
P
E
T
S
R
H
T
G
D
T
S
Site 72
T683
V
P
E
T
S
R
H
T
G
D
T
S
N
G
C
Site 73
T686
T
S
R
H
T
G
D
T
S
N
G
C
A
D
V
Site 74
S709
Q
L
I
A
D
A
V
S
S
P
N
H
G
D
S
Site 75
S710
L
I
A
D
A
V
S
S
P
N
H
G
D
S
P
Site 76
S716
S
S
P
N
H
G
D
S
P
N
L
L
I
A
D
Site 77
T758
H
P
A
V
H
T
K
T
D
H
S
V
A
S
S
Site 78
S761
V
H
T
K
T
D
H
S
V
A
S
S
P
S
S
Site 79
S764
K
T
D
H
S
V
A
S
S
P
S
S
A
I
S
Site 80
S765
T
D
H
S
V
A
S
S
P
S
S
A
I
S
T
Site 81
S767
H
S
V
A
S
S
P
S
S
A
I
S
T
A
T
Site 82
S768
S
V
A
S
S
P
S
S
A
I
S
T
A
T
P
Site 83
S771
S
S
P
S
S
A
I
S
T
A
T
P
S
P
K
Site 84
T772
S
P
S
S
A
I
S
T
A
T
P
S
P
K
S
Site 85
T774
S
S
A
I
S
T
A
T
P
S
P
K
S
T
E
Site 86
S776
A
I
S
T
A
T
P
S
P
K
S
T
E
Q
R
Site 87
S779
T
A
T
P
S
P
K
S
T
E
Q
R
S
I
N
Site 88
T780
A
T
P
S
P
K
S
T
E
Q
R
S
I
N
S
Site 89
S784
P
K
S
T
E
Q
R
S
I
N
S
V
T
S
L
Site 90
S787
T
E
Q
R
S
I
N
S
V
T
S
L
N
S
P
Site 91
T789
Q
R
S
I
N
S
V
T
S
L
N
S
P
H
S
Site 92
S790
R
S
I
N
S
V
T
S
L
N
S
P
H
S
G
Site 93
S793
N
S
V
T
S
L
N
S
P
H
S
G
L
H
T
Site 94
S796
T
S
L
N
S
P
H
S
G
L
H
T
V
N
G
Site 95
T800
S
P
H
S
G
L
H
T
V
N
G
E
G
L
G
Site 96
S809
N
G
E
G
L
G
K
S
Q
S
S
T
K
V
D
Site 97
S811
E
G
L
G
K
S
Q
S
S
T
K
V
D
L
P
Site 98
T813
L
G
K
S
Q
S
S
T
K
V
D
L
P
L
A
Site 99
S821
K
V
D
L
P
L
A
S
H
R
S
T
S
Q
I
Site 100
S824
L
P
L
A
S
H
R
S
T
S
Q
I
L
P
S
Site 101
T825
P
L
A
S
H
R
S
T
S
Q
I
L
P
S
M
Site 102
S826
L
A
S
H
R
S
T
S
Q
I
L
P
S
M
S
Site 103
S856
N
P
G
K
N
G
L
S
N
S
C
I
L
L
D
Site 104
S858
G
K
N
G
L
S
N
S
C
I
L
L
D
K
C
Site 105
T872
C
P
P
P
R
P
P
T
S
P
Y
P
P
L
P
Site 106
S873
P
P
P
R
P
P
T
S
P
Y
P
P
L
P
K
Site 107
Y875
P
R
P
P
T
S
P
Y
P
P
L
P
K
D
K
Site 108
T887
K
D
K
L
N
P
P
T
P
S
I
Y
L
E
N
Site 109
Y891
N
P
P
T
P
S
I
Y
L
E
N
K
R
D
A
Site 110
T908
P
P
L
H
Q
F
C
T
N
P
K
N
P
V
T
Site 111
T915
T
N
P
K
N
P
V
T
V
I
R
G
L
A
G
Site 112
T935
L
G
L
F
S
T
K
T
L
V
E
A
N
N
E
Site 113
T962
A
D
E
N
W
D
P
T
G
T
K
K
I
W
R
Site 114
T977
C
E
S
N
R
S
H
T
T
I
A
K
Y
A
Q
Site 115
Y982
S
H
T
T
I
A
K
Y
A
Q
Y
Q
A
S
S
Site 116
Y985
T
I
A
K
Y
A
Q
Y
Q
A
S
S
F
Q
E
Site 117
S988
K
Y
A
Q
Y
Q
A
S
S
F
Q
E
S
L
R
Site 118
S989
Y
A
Q
Y
Q
A
S
S
F
Q
E
S
L
R
E
Site 119
S993
Q
A
S
S
F
Q
E
S
L
R
E
E
N
E
K
Site 120
S1008
R
T
Q
H
K
D
H
S
D
N
E
S
T
S
S
Site 121
S1012
K
D
H
S
D
N
E
S
T
S
S
E
N
S
G
Site 122
S1014
H
S
D
N
E
S
T
S
S
E
N
S
G
R
R
Site 123
S1015
S
D
N
E
S
T
S
S
E
N
S
G
R
R
R
Site 124
S1018
E
S
T
S
S
E
N
S
G
R
R
R
K
G
P
Site 125
T1028
R
R
K
G
P
F
K
T
I
K
F
G
T
N
I
Site 126
T1033
F
K
T
I
K
F
G
T
N
I
D
L
S
D
N
Site 127
S1038
F
G
T
N
I
D
L
S
D
N
K
K
W
K
L
Site 128
Y1082
G
M
N
T
V
Q
L
Y
M
K
V
P
G
S
R
Site 129
S1088
L
Y
M
K
V
P
G
S
R
T
P
G
H
Q
E
Site 130
T1090
M
K
V
P
G
S
R
T
P
G
H
Q
E
N
N
Site 131
Y1148
W
P
N
L
E
D
L
Y
E
A
N
V
P
V
Y
Site 132
Y1203
Y
K
L
A
V
E
R
Y
E
W
N
K
L
K
S
Site 133
S1210
Y
E
W
N
K
L
K
S
V
K
S
P
V
P
M
Site 134
S1213
N
K
L
K
S
V
K
S
P
V
P
M
V
H
L
Site 135
S1231
M
A
R
N
I
K
V
S
D
P
K
L
F
E
M
Site 136
T1252
K
I
L
K
Q
Y
Q
T
L
R
E
A
L
V
A
Site 137
Y1277
T
N
D
E
P
A
H
Y
C
S
I
C
E
V
E
Site 138
T1312
C
H
D
C
A
R
K
T
S
K
S
L
E
N
F
Site 139
S1313
H
D
C
A
R
K
T
S
K
S
L
E
N
F
V
Site 140
S1315
C
A
R
K
T
S
K
S
L
E
N
F
V
V
L
Site 141
S1342
D
Q
F
T
L
A
L
S
L
S
S
S
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation