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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0286
Full Name:
Transmembrane protein 194A
Alias:
DKFZp686N1768; K0286; TM194
Type:
Uncharacterized protein
Mass (Da):
50640
Number AA:
444
UniProt ID:
O14524
International Prot ID:
IPI00215874
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
V
G
P
G
P
W
G
S
G
V
G
G
G
G
T
Site 2
S55
N
V
V
M
L
Q
E
S
Q
V
C
E
K
R
A
Site 3
S63
Q
V
C
E
K
R
A
S
Q
Q
F
C
Y
T
N
Site 4
Y68
R
A
S
Q
Q
F
C
Y
T
N
V
L
I
P
K
Site 5
S89
R
I
Q
I
R
V
N
S
S
R
L
V
R
V
T
Site 6
T96
S
S
R
L
V
R
V
T
Q
V
E
N
E
E
K
Site 7
S111
L
K
E
L
E
Q
F
S
I
W
N
F
F
S
S
Site 8
S118
S
I
W
N
F
F
S
S
F
L
K
E
K
L
N
Site 9
T127
L
K
E
K
L
N
D
T
Y
V
N
V
G
L
Y
Site 10
Y128
K
E
K
L
N
D
T
Y
V
N
V
G
L
Y
S
Site 11
Y151
I
I
E
K
D
T
K
Y
S
V
I
V
I
R
R
Site 12
S183
C
G
D
L
L
S
R
S
Q
I
F
Y
Y
S
T
Site 13
Y187
L
S
R
S
Q
I
F
Y
Y
S
T
G
M
T
V
Site 14
Y188
S
R
S
Q
I
F
Y
Y
S
T
G
M
T
V
G
Site 15
Y268
S
F
A
V
C
Y
K
Y
G
P
L
E
N
E
R
Site 16
S276
G
P
L
E
N
E
R
S
I
N
L
L
T
W
T
Site 17
T343
P
V
P
P
R
L
L
T
E
E
E
Y
R
I
Q
Site 18
Y347
R
L
L
T
E
E
E
Y
R
I
Q
G
E
V
E
Site 19
S368
E
L
R
E
F
C
N
S
P
D
C
S
A
W
K
Site 20
T376
P
D
C
S
A
W
K
T
V
S
R
I
Q
S
P
Site 21
S378
C
S
A
W
K
T
V
S
R
I
Q
S
P
K
R
Site 22
S382
K
T
V
S
R
I
Q
S
P
K
R
F
A
D
F
Site 23
T397
V
E
G
S
S
H
L
T
P
N
E
V
S
V
H
Site 24
S402
H
L
T
P
N
E
V
S
V
H
E
Q
E
Y
G
Site 25
Y420
I
I
A
Q
D
E
I
Y
E
E
A
S
S
E
E
Site 26
S424
D
E
I
Y
E
E
A
S
S
E
E
E
D
S
Y
Site 27
S425
E
I
Y
E
E
A
S
S
E
E
E
D
S
Y
S
Site 28
S430
A
S
S
E
E
E
D
S
Y
S
R
C
P
A
I
Site 29
Y431
S
S
E
E
E
D
S
Y
S
R
C
P
A
I
T
Site 30
S432
S
E
E
E
D
S
Y
S
R
C
P
A
I
T
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation