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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM24
Full Name:
C2 domain-containing protein 2-like
Alias:
C2CD2-like; DLNB23; KIAA0285; TMM24; Transmembrane protein 24
Type:
Unknown function
Mass (Da):
76181
Number AA:
706
UniProt ID:
O14523
International Prot ID:
IPI00791103
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S59
L
A
G
E
P
A
G
S
L
R
E
L
G
V
W
Site 2
S68
R
E
L
G
V
W
R
S
L
L
R
L
R
A
T
Site 3
T75
S
L
L
R
L
R
A
T
R
A
G
A
A
E
E
Site 4
S97
A
S
L
F
A
F
K
S
F
R
E
N
W
Q
R
Site 5
S119
E
Q
A
C
R
N
G
S
S
I
Q
I
A
F
E
Site 6
S136
P
Q
L
P
P
R
A
S
I
S
H
V
T
C
V
Site 7
S166
E
E
V
R
F
P
V
S
V
T
Q
Q
S
P
A
Site 8
S171
P
V
S
V
T
Q
Q
S
P
A
A
V
S
M
E
Site 9
T185
E
T
Y
H
V
T
L
T
L
P
P
T
Q
L
E
Site 10
S206
P
G
E
G
L
L
I
S
W
A
F
T
D
R
P
Site 11
T218
D
R
P
D
L
S
L
T
V
L
P
K
L
Q
A
Site 12
S236
G
E
E
Q
V
E
L
S
T
I
E
E
L
I
K
Site 13
S269
A
P
G
G
L
V
P
S
E
K
P
P
M
M
P
Site 14
S296
F
L
R
Q
L
R
A
S
H
L
G
N
E
L
E
Site 15
S330
T
K
P
A
R
A
G
S
E
V
E
W
T
E
D
Site 16
T335
A
G
S
E
V
E
W
T
E
D
L
A
L
D
L
Site 17
S346
A
L
D
L
G
P
Q
S
R
E
L
T
L
K
V
Site 18
T350
G
P
Q
S
R
E
L
T
L
K
V
L
R
S
S
Site 19
S356
L
T
L
K
V
L
R
S
S
S
C
G
D
T
E
Site 20
S357
T
L
K
V
L
R
S
S
S
C
G
D
T
E
L
Site 21
S358
L
K
V
L
R
S
S
S
C
G
D
T
E
L
L
Site 22
T362
R
S
S
S
C
G
D
T
E
L
L
G
Q
A
T
Site 23
T369
T
E
L
L
G
Q
A
T
L
P
V
G
S
P
S
Site 24
S374
Q
A
T
L
P
V
G
S
P
S
R
P
L
S
R
Site 25
S376
T
L
P
V
G
S
P
S
R
P
L
S
R
R
Q
Site 26
S380
G
S
P
S
R
P
L
S
R
R
Q
L
C
P
L
Site 27
T388
R
R
Q
L
C
P
L
T
P
G
P
G
K
A
L
Site 28
T400
K
A
L
G
P
A
A
T
M
A
V
E
L
H
Y
Site 29
Y407
T
M
A
V
E
L
H
Y
E
E
G
S
P
R
N
Site 30
S411
E
L
H
Y
E
E
G
S
P
R
N
L
G
T
P
Site 31
T417
G
S
P
R
N
L
G
T
P
T
S
S
T
P
R
Site 32
T419
P
R
N
L
G
T
P
T
S
S
T
P
R
P
S
Site 33
S420
R
N
L
G
T
P
T
S
S
T
P
R
P
S
I
Site 34
S421
N
L
G
T
P
T
S
S
T
P
R
P
S
I
T
Site 35
T422
L
G
T
P
T
S
S
T
P
R
P
S
I
T
P
Site 36
S426
T
S
S
T
P
R
P
S
I
T
P
T
K
K
I
Site 37
T428
S
T
P
R
P
S
I
T
P
T
K
K
I
E
L
Site 38
T430
P
R
P
S
I
T
P
T
K
K
I
E
L
D
R
Site 39
T438
K
K
I
E
L
D
R
T
I
M
P
D
G
T
I
Site 40
T448
P
D
G
T
I
V
T
T
V
T
T
V
Q
S
R
Site 41
T450
G
T
I
V
T
T
V
T
T
V
Q
S
R
P
R
Site 42
S464
R
I
D
G
K
L
D
S
P
S
R
S
P
S
K
Site 43
S466
D
G
K
L
D
S
P
S
R
S
P
S
K
V
E
Site 44
S468
K
L
D
S
P
S
R
S
P
S
K
V
E
V
T
Site 45
S470
D
S
P
S
R
S
P
S
K
V
E
V
T
E
K
Site 46
T475
S
P
S
K
V
E
V
T
E
K
T
T
T
V
L
Site 47
T478
K
V
E
V
T
E
K
T
T
T
V
L
S
E
S
Site 48
T480
E
V
T
E
K
T
T
T
V
L
S
E
S
S
G
Site 49
S483
E
K
T
T
T
V
L
S
E
S
S
G
P
S
N
Site 50
S485
T
T
T
V
L
S
E
S
S
G
P
S
N
T
S
Site 51
S486
T
T
V
L
S
E
S
S
G
P
S
N
T
S
H
Site 52
S489
L
S
E
S
S
G
P
S
N
T
S
H
S
S
S
Site 53
T491
E
S
S
G
P
S
N
T
S
H
S
S
S
R
D
Site 54
S492
S
S
G
P
S
N
T
S
H
S
S
S
R
D
S
Site 55
S494
G
P
S
N
T
S
H
S
S
S
R
D
S
H
L
Site 56
S495
P
S
N
T
S
H
S
S
S
R
D
S
H
L
S
Site 57
S496
S
N
T
S
H
S
S
S
R
D
S
H
L
S
N
Site 58
S499
S
H
S
S
S
R
D
S
H
L
S
N
G
L
D
Site 59
S502
S
S
R
D
S
H
L
S
N
G
L
D
P
V
A
Site 60
T517
E
T
A
I
R
Q
L
T
E
P
S
G
R
V
A
Site 61
S520
I
R
Q
L
T
E
P
S
G
R
V
A
K
K
T
Site 62
T527
S
G
R
V
A
K
K
T
P
T
K
R
S
T
L
Site 63
T529
R
V
A
K
K
T
P
T
K
R
S
T
L
I
I
Site 64
S532
K
K
T
P
T
K
R
S
T
L
I
I
S
G
V
Site 65
T533
K
T
P
T
K
R
S
T
L
I
I
S
G
V
S
Site 66
S562
Y
A
A
S
L
E
A
S
V
Q
D
D
A
G
T
Site 67
T569
S
V
Q
D
D
A
G
T
S
G
G
P
S
S
P
Site 68
S570
V
Q
D
D
A
G
T
S
G
G
P
S
S
P
P
Site 69
S574
A
G
T
S
G
G
P
S
S
P
P
S
D
P
P
Site 70
S575
G
T
S
G
G
P
S
S
P
P
S
D
P
P
A
Site 71
S578
G
G
P
S
S
P
P
S
D
P
P
A
M
S
P
Site 72
S584
P
S
D
P
P
A
M
S
P
G
P
L
D
A
L
Site 73
S592
P
G
P
L
D
A
L
S
S
P
T
S
V
Q
E
Site 74
S593
G
P
L
D
A
L
S
S
P
T
S
V
Q
E
A
Site 75
S596
D
A
L
S
S
P
T
S
V
Q
E
A
D
E
T
Site 76
T603
S
V
Q
E
A
D
E
T
T
R
S
D
I
S
E
Site 77
S606
E
A
D
E
T
T
R
S
D
I
S
E
R
P
S
Site 78
S609
E
T
T
R
S
D
I
S
E
R
P
S
V
D
D
Site 79
S613
S
D
I
S
E
R
P
S
V
D
D
I
E
S
E
Site 80
S619
P
S
V
D
D
I
E
S
E
T
G
S
T
G
A
Site 81
T621
V
D
D
I
E
S
E
T
G
S
T
G
A
L
E
Site 82
S623
D
I
E
S
E
T
G
S
T
G
A
L
E
T
R
Site 83
T624
I
E
S
E
T
G
S
T
G
A
L
E
T
R
S
Site 84
S631
T
G
A
L
E
T
R
S
L
K
D
H
K
V
S
Site 85
S638
S
L
K
D
H
K
V
S
F
L
R
S
G
T
K
Site 86
S642
H
K
V
S
F
L
R
S
G
T
K
L
I
F
R
Site 87
T644
V
S
F
L
R
S
G
T
K
L
I
F
R
R
R
Site 88
S660
R
Q
K
E
A
G
L
S
Q
S
H
D
D
L
S
Site 89
S662
K
E
A
G
L
S
Q
S
H
D
D
L
S
N
A
Site 90
S667
S
Q
S
H
D
D
L
S
N
A
T
A
T
P
S
Site 91
T670
H
D
D
L
S
N
A
T
A
T
P
S
V
R
K
Site 92
T672
D
L
S
N
A
T
A
T
P
S
V
R
K
K
A
Site 93
S674
S
N
A
T
A
T
P
S
V
R
K
K
A
G
S
Site 94
S681
S
V
R
K
K
A
G
S
F
S
R
R
L
I
K
Site 95
S683
R
K
K
A
G
S
F
S
R
R
L
I
K
R
F
Site 96
S691
R
R
L
I
K
R
F
S
F
K
S
K
P
K
A
Site 97
S694
I
K
R
F
S
F
K
S
K
P
K
A
N
G
N
Site 98
S703
P
K
A
N
G
N
P
S
P
Q
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation