PhosphoNET

           
Protein Info 
   
Short Name:  SOCS7
Full Name:  Suppressor of cytokine signaling 7
Alias:  NAP4; NAP-4; Nck, Ash and phospholipase C binding protein; Nck, Ash and phospholipase C gamma-binding protein; NCKAP4; Nck-associated protein 4; SOCS6
Type:  Inhibitor protein
Mass (Da):  62969
Number AA:  485
UniProt ID:  O14512
International Prot ID:  IPI00022329
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005886   Uniprot OncoNet
Molecular Function:  GO:0017124     PhosphoSite+ KinaseNET
Biological Process:  GO:0007242  GO:0019941  GO:0009968 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S24AAPEPGPSELLCPRH
Site 2S122LVLEGLESEAESLET
Site 3S126GLESEAESLETNSCS
Site 4T129SEAESLETNSCSEEE
Site 5S131AESLETNSCSEEELS
Site 6S133SLETNSCSEEELSSP
Site 7S138SCSEEELSSPGRGGG
Site 8S139CSEEELSSPGRGGGG
Site 9S176LVPLGRLSRGEQQQQ
Site 10S205LRPLAGPSRKGSFKI
Site 11S209AGPSRKGSFKIRLSR
Site 12S215GSFKIRLSRLFRTKS
Site 13S222SRLFRTKSCNGGSGG
Site 14T233GSGGGDGTGKRPSGE
Site 15S238DGTGKRPSGELAASA
Site 16S254SLTDMGGSAGRELDA
Site 17T268AGRKPKLTRTQSAFS
Site 18T270RKPKLTRTQSAFSPV
Site 19S272PKLTRTQSAFSPVSF
Site 20S275TRTQSAFSPVSFSPL
Site 21S296SLVDVDISQRGLTSP
Site 22T301DISQRGLTSPHPPTP
Site 23S302ISQRGLTSPHPPTPP
Site 24T307LTSPHPPTPPPPPRR
Site 25S315PPPPPRRSLSLLDDI
Site 26S317PPPRRSLSLLDDISG
Site 27S341PMGSSLQSFPLPPPP
Site 28S367APIRAAESLHSQPPQ
Site 29S370RAAESLHSQPPQHLQ
Site 30Y381QHLQCPLYRPDSSSF
Site 31S385CPLYRPDSSSFAASL
Site 32S386PLYRPDSSSFAASLR
Site 33S387LYRPDSSSFAASLRE
Site 34S391DSSSFAASLRELEKC
Site 35S421LKGKPDGSFLVRDSS
Site 36S427GSFLVRDSSDPRYIL
Site 37S428SFLVRDSSDPRYILS
Site 38Y432RDSSDPRYILSLSFR
Site 39S435SDPRYILSLSFRSQG
Site 40S437PRYILSLSFRSQGIT
Site 41S440ILSLSFRSQGITHHT
Site 42T444SFRSQGITHHTRMEH
Site 43Y452HHTRMEHYRGTFSLW
Site 44T455RMEHYRGTFSLWCHP
Site 45S457EHYRGTFSLWCHPKF
Site 46S470KFEDRCQSVVEFIKR
Site 47Y489SKNGKFLYFLRSRVP
Site 48S493KFLYFLRSRVPGLPP
Site 49Y507PTPVQLLYPVSRFSN
Site 50S510VQLLYPVSRFSNVKS
Site 51S513LYPVSRFSNVKSLQH
Site 52S517SRFSNVKSLQHLCRF
Site 53S546PLPKPLISYIRKFYY
Site 54Y547LPKPLISYIRKFYYY
Site 55Y552ISYIRKFYYYDPQEE
Site 56Y553SYIRKFYYYDPQEEV
Site 57Y554YIRKFYYYDPQEEVY
Site 58Y561YDPQEEVYLSLKEAQ
Site 59S563PQEEVYLSLKEAQLI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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