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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAD1
Full Name:
Ladinin-1
Alias:
120 kDa linear IgA bullous dermatosis antigen; 97 kDa linear IgA bullous dermatosis antigen; Lad-1; LadA; ladinin 1; linear IgA bullous dermatosis antigen; linear IgA disease antigen homolog
Type:
Extracellular matrix protein
Mass (Da):
57131
Number AA:
517
UniProt ID:
O00515
International Prot ID:
IPI00386700
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005604
Uniprot
OncoNet
Molecular Function:
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
V
S
R
K
D
W
S
A
L
S
S
L
A
R
Site 2
S13
K
D
W
S
A
L
S
S
L
A
R
Q
R
T
L
Site 3
T19
S
S
L
A
R
Q
R
T
L
E
D
E
E
E
Q
Site 4
S38
R
R
R
H
R
N
L
S
S
T
T
D
D
E
A
Site 5
S39
R
R
H
R
N
L
S
S
T
T
D
D
E
A
P
Site 6
T40
R
H
R
N
L
S
S
T
T
D
D
E
A
P
R
Site 7
T41
H
R
N
L
S
S
T
T
D
D
E
A
P
R
L
Site 8
S49
D
D
E
A
P
R
L
S
Q
N
G
D
R
Q
A
Site 9
S57
Q
N
G
D
R
Q
A
S
A
S
E
R
L
P
S
Site 10
S59
G
D
R
Q
A
S
A
S
E
R
L
P
S
V
E
Site 11
S64
S
A
S
E
R
L
P
S
V
E
E
A
E
V
P
Site 12
S78
P
K
P
L
P
P
A
S
K
D
E
D
E
D
I
Site 13
S87
D
E
D
E
D
I
Q
S
I
L
R
T
R
Q
E
Site 14
T91
D
I
Q
S
I
L
R
T
R
Q
E
R
R
Q
R
Site 15
S121
E
A
E
E
G
R
N
S
L
S
P
V
Q
A
T
Site 16
S123
E
E
G
R
N
S
L
S
P
V
Q
A
T
Q
K
Site 17
T128
S
L
S
P
V
Q
A
T
Q
K
P
L
V
S
K
Site 18
S134
A
T
Q
K
P
L
V
S
K
K
E
L
E
I
P
Site 19
S147
I
P
P
R
R
R
L
S
R
E
Q
R
G
P
W
Site 20
S160
P
W
A
L
E
E
E
S
L
V
G
R
E
P
E
Site 21
S177
K
K
G
V
P
E
K
S
P
V
L
E
K
S
S
Site 22
S183
K
S
P
V
L
E
K
S
S
M
P
K
K
T
A
Site 23
S184
S
P
V
L
E
K
S
S
M
P
K
K
T
A
P
Site 24
T189
K
S
S
M
P
K
K
T
A
P
E
K
S
L
V
Site 25
S194
K
K
T
A
P
E
K
S
L
V
S
D
K
T
S
Site 26
S197
A
P
E
K
S
L
V
S
D
K
T
S
I
S
E
Site 27
T200
K
S
L
V
S
D
K
T
S
I
S
E
K
V
L
Site 28
S201
S
L
V
S
D
K
T
S
I
S
E
K
V
L
A
Site 29
S203
V
S
D
K
T
S
I
S
E
K
V
L
A
S
E
Site 30
S209
I
S
E
K
V
L
A
S
E
K
T
S
L
S
E
Site 31
S215
A
S
E
K
T
S
L
S
E
K
I
A
V
S
E
Site 32
S221
L
S
E
K
I
A
V
S
E
K
R
N
S
S
E
Site 33
S226
A
V
S
E
K
R
N
S
S
E
K
K
S
V
L
Site 34
S227
V
S
E
K
R
N
S
S
E
K
K
S
V
L
E
Site 35
S231
R
N
S
S
E
K
K
S
V
L
E
K
T
S
V
Site 36
T236
K
K
S
V
L
E
K
T
S
V
S
E
K
S
L
Site 37
S237
K
S
V
L
E
K
T
S
V
S
E
K
S
L
A
Site 38
S239
V
L
E
K
T
S
V
S
E
K
S
L
A
P
G
Site 39
S242
K
T
S
V
S
E
K
S
L
A
P
G
M
A
L
Site 40
S251
A
P
G
M
A
L
G
S
G
R
R
L
V
S
E
Site 41
S257
G
S
G
R
R
L
V
S
E
K
A
S
I
F
E
Site 42
S269
I
F
E
K
A
L
A
S
E
K
S
P
T
A
D
Site 43
S272
K
A
L
A
S
E
K
S
P
T
A
D
A
K
P
Site 44
T274
L
A
S
E
K
S
P
T
A
D
A
K
P
A
P
Site 45
T285
K
P
A
P
K
R
A
T
A
S
E
Q
P
L
A
Site 46
S287
A
P
K
R
A
T
A
S
E
Q
P
L
A
Q
E
Site 47
S298
L
A
Q
E
P
P
A
S
G
G
S
P
A
T
T
Site 48
S301
E
P
P
A
S
G
G
S
P
A
T
T
K
E
Q
Site 49
T305
S
G
G
S
P
A
T
T
K
E
Q
R
G
R
A
Site 50
S320
L
P
G
K
N
L
P
S
L
A
K
Q
G
A
S
Site 51
T331
Q
G
A
S
D
P
P
T
V
A
S
R
L
P
P
Site 52
S334
S
D
P
P
T
V
A
S
R
L
P
P
V
T
L
Site 53
S347
T
L
Q
V
K
I
P
S
K
E
E
E
A
D
M
Site 54
S355
K
E
E
E
A
D
M
S
S
P
T
Q
R
T
Y
Site 55
S356
E
E
E
A
D
M
S
S
P
T
Q
R
T
Y
S
Site 56
T358
E
A
D
M
S
S
P
T
Q
R
T
Y
S
S
S
Site 57
T361
M
S
S
P
T
Q
R
T
Y
S
S
S
L
K
R
Site 58
Y362
S
S
P
T
Q
R
T
Y
S
S
S
L
K
R
S
Site 59
S363
S
P
T
Q
R
T
Y
S
S
S
L
K
R
S
S
Site 60
S364
P
T
Q
R
T
Y
S
S
S
L
K
R
S
S
P
Site 61
S365
T
Q
R
T
Y
S
S
S
L
K
R
S
S
P
R
Site 62
S369
Y
S
S
S
L
K
R
S
S
P
R
T
I
S
F
Site 63
S370
S
S
S
L
K
R
S
S
P
R
T
I
S
F
R
Site 64
T373
L
K
R
S
S
P
R
T
I
S
F
R
M
K
P
Site 65
S375
R
S
S
P
R
T
I
S
F
R
M
K
P
K
K
Site 66
S385
M
K
P
K
K
E
N
S
E
T
T
L
T
R
S
Site 67
T387
P
K
K
E
N
S
E
T
T
L
T
R
S
A
S
Site 68
T388
K
K
E
N
S
E
T
T
L
T
R
S
A
S
M
Site 69
T390
E
N
S
E
T
T
L
T
R
S
A
S
M
K
L
Site 70
S392
S
E
T
T
L
T
R
S
A
S
M
K
L
P
D
Site 71
S394
T
T
L
T
R
S
A
S
M
K
L
P
D
N
T
Site 72
T401
S
M
K
L
P
D
N
T
V
K
L
G
E
K
L
Site 73
Y411
L
G
E
K
L
E
R
Y
H
T
A
I
R
R
S
Site 74
T413
E
K
L
E
R
Y
H
T
A
I
R
R
S
E
S
Site 75
S418
Y
H
T
A
I
R
R
S
E
S
V
K
S
R
G
Site 76
S420
T
A
I
R
R
S
E
S
V
K
S
R
G
L
P
Site 77
S423
R
R
S
E
S
V
K
S
R
G
L
P
C
T
E
Site 78
S440
V
A
P
V
G
V
A
S
K
R
H
L
F
E
K
Site 79
S459
Q
S
R
A
E
P
A
S
S
R
K
E
N
L
R
Site 80
S460
S
R
A
E
P
A
S
S
R
K
E
N
L
R
L
Site 81
S468
R
K
E
N
L
R
L
S
G
V
V
T
S
R
L
Site 82
S480
S
R
L
N
L
W
I
S
R
T
Q
E
S
G
D
Site 83
T482
L
N
L
W
I
S
R
T
Q
E
S
G
D
Q
D
Site 84
S485
W
I
S
R
T
Q
E
S
G
D
Q
D
P
Q
E
Site 85
T503
A
S
S
A
T
E
R
T
Q
W
G
Q
K
S
D
Site 86
S509
R
T
Q
W
G
Q
K
S
D
S
S
L
D
A
E
Site 87
S511
Q
W
G
Q
K
S
D
S
S
L
D
A
E
V
_
Site 88
S512
W
G
Q
K
S
D
S
S
L
D
A
E
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation