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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KPNA3
Full Name:
Importin subunit alpha-3
Alias:
IMA3; Importin alpha-3 subunit; SRP1-gamma
Type:
Chaperone, Adaptor/scaffold
Mass (Da):
57811
Number AA:
521
UniProt ID:
O00505
International Prot ID:
IPI00299033
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005643
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0008139
GO:0008565
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006607
GO:0006461
GO:0006606
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
E
N
P
S
L
E
N
H
R
I
K
Site 2
S14
L
E
N
H
R
I
K
S
F
K
N
K
G
R
D
Site 3
T24
N
K
G
R
D
V
E
T
M
R
R
H
R
N
E
Site 4
T33
R
R
H
R
N
E
V
T
V
E
L
R
K
N
K
Site 5
S56
R
N
V
P
Q
E
E
S
L
E
D
S
D
V
D
Site 6
S60
Q
E
E
S
L
E
D
S
D
V
D
A
D
F
K
Site 7
S100
Q
A
A
R
K
L
L
S
S
D
R
N
P
P
I
Site 8
S101
A
A
R
K
L
L
S
S
D
R
N
P
P
I
D
Site 9
S130
L
E
R
D
D
N
P
S
L
Q
F
E
A
A
W
Site 10
S168
L
F
L
R
L
L
R
S
P
H
Q
N
V
C
E
Site 11
T239
D
P
P
P
P
M
E
T
V
Q
E
I
L
P
A
Site 12
Y268
D
T
V
W
A
L
S
Y
L
T
D
G
G
N
E
Site 13
T313
R
A
V
G
N
I
V
T
G
T
D
E
Q
T
Q
Site 14
T315
V
G
N
I
V
T
G
T
D
E
Q
T
Q
V
V
Site 15
T319
V
T
G
T
D
E
Q
T
Q
V
V
L
N
C
D
Site 16
S336
S
H
F
P
N
L
L
S
H
P
K
E
K
I
N
Site 17
S398
A
I
S
N
L
T
I
S
G
R
K
D
Q
V
E
Site 18
Y406
G
R
K
D
Q
V
E
Y
L
V
Q
Q
N
V
I
Site 19
S425
N
L
L
S
V
K
D
S
Q
V
V
Q
V
V
L
Site 20
Y474
Q
H
E
N
E
D
I
Y
K
L
A
F
E
I
I
Site 21
Y484
A
F
E
I
I
D
Q
Y
F
S
G
D
D
I
D
Site 22
S486
E
I
I
D
Q
Y
F
S
G
D
D
I
D
E
D
Site 23
T501
P
C
L
I
P
E
A
T
Q
G
G
T
Y
N
F
Site 24
Y506
E
A
T
Q
G
G
T
Y
N
F
D
P
T
A
N
Site 25
T511
G
T
Y
N
F
D
P
T
A
N
L
Q
T
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation