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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EXOC5
Full Name:
Exocyst complex component 5
Alias:
Exocyst complex component Sec10; PRO1912; SEC10; SEC10L1; SEC10P
Type:
Vesicle protein
Mass (Da):
81853
Number AA:
708
UniProt ID:
O00471
International Prot ID:
IPI00829808
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006887
GO:0006892
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
A
T
T
A
E
L
F
E
E
Site 2
T4
_
_
_
_
M
A
T
T
A
E
L
F
E
E
P
Site 3
Y17
E
P
F
V
A
D
E
Y
I
E
R
L
V
W
R
Site 4
T25
I
E
R
L
V
W
R
T
P
G
G
G
S
R
G
Site 5
S88
K
V
Q
E
L
Q
K
S
N
Q
V
A
F
Q
H
Site 6
Y105
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Site 7
T122
D
Q
L
E
G
V
N
T
P
R
Q
R
A
V
E
Site 8
Y136
E
A
Q
K
L
M
K
Y
F
N
E
F
L
D
G
Site 9
S147
F
L
D
G
E
L
K
S
D
V
F
T
N
S
E
Site 10
T151
E
L
K
S
D
V
F
T
N
S
E
K
I
K
E
Site 11
S153
K
S
D
V
F
T
N
S
E
K
I
K
E
A
A
Site 12
S179
E
L
P
F
D
R
F
S
E
V
K
S
K
I
A
Site 13
S183
D
R
F
S
E
V
K
S
K
I
A
S
K
Y
H
Site 14
S187
E
V
K
S
K
I
A
S
K
Y
H
D
L
E
C
Site 15
Y189
K
S
K
I
A
S
K
Y
H
D
L
E
C
Q
L
Site 16
S202
Q
L
I
Q
E
F
T
S
A
Q
R
R
G
E
I
Site 17
S210
A
Q
R
R
G
E
I
S
R
M
R
E
V
A
A
Site 18
Y225
V
L
L
H
F
K
G
Y
S
H
C
V
D
V
Y
Site 19
Y232
Y
S
H
C
V
D
V
Y
I
K
Q
C
Q
E
G
Site 20
Y241
K
Q
C
Q
E
G
A
Y
L
R
N
D
I
F
E
Site 21
S266
K
Q
V
G
D
I
F
S
N
P
E
T
V
L
A
Site 22
S286
V
F
E
I
K
L
Q
S
F
V
K
E
Q
L
E
Site 23
S298
Q
L
E
E
C
R
K
S
D
A
E
Q
Y
L
K
Site 24
Y308
E
Q
Y
L
K
N
L
Y
D
L
Y
T
R
T
T
Site 25
Y311
L
K
N
L
Y
D
L
Y
T
R
T
T
N
L
S
Site 26
T312
K
N
L
Y
D
L
Y
T
R
T
T
N
L
S
S
Site 27
T314
L
Y
D
L
Y
T
R
T
T
N
L
S
S
K
L
Site 28
T315
Y
D
L
Y
T
R
T
T
N
L
S
S
K
L
M
Site 29
S318
Y
T
R
T
T
N
L
S
S
K
L
M
E
F
N
Site 30
T328
L
M
E
F
N
L
G
T
D
K
Q
T
F
L
S
Site 31
T332
N
L
G
T
D
K
Q
T
F
L
S
K
L
I
K
Site 32
S335
T
D
K
Q
T
F
L
S
K
L
I
K
S
I
F
Site 33
Y345
I
K
S
I
F
I
S
Y
L
E
N
Y
I
E
V
Site 34
Y349
F
I
S
Y
L
E
N
Y
I
E
V
E
T
G
Y
Site 35
Y356
Y
I
E
V
E
T
G
Y
L
K
S
R
S
A
M
Site 36
S359
V
E
T
G
Y
L
K
S
R
S
A
M
I
L
Q
Site 37
S361
T
G
Y
L
K
S
R
S
A
M
I
L
Q
R
Y
Site 38
Y368
S
A
M
I
L
Q
R
Y
Y
D
S
K
N
H
Q
Site 39
Y369
A
M
I
L
Q
R
Y
Y
D
S
K
N
H
Q
K
Site 40
S378
S
K
N
H
Q
K
R
S
I
G
T
G
G
I
Q
Site 41
T395
K
E
R
I
R
Q
R
T
N
L
P
L
G
P
S
Site 42
T405
P
L
G
P
S
I
D
T
H
G
E
T
F
L
S
Site 43
T409
S
I
D
T
H
G
E
T
F
L
S
Q
E
V
V
Site 44
S412
T
H
G
E
T
F
L
S
Q
E
V
V
V
N
L
Site 45
S434
F
E
R
C
H
R
L
S
D
P
S
D
L
P
R
Site 46
S437
C
H
R
L
S
D
P
S
D
L
P
R
N
A
F
Site 47
S472
T
G
L
A
G
I
P
S
S
D
S
R
N
A
N
Site 48
S473
G
L
A
G
I
P
S
S
D
S
R
N
A
N
L
Site 49
S475
A
G
I
P
S
S
D
S
R
N
A
N
L
Y
F
Site 50
Y481
D
S
R
N
A
N
L
Y
F
L
D
V
V
Q
Q
Site 51
S509
D
H
L
M
P
L
I
S
S
S
P
K
L
S
E
Site 52
S510
H
L
M
P
L
I
S
S
S
P
K
L
S
E
C
Site 53
S515
I
S
S
S
P
K
L
S
E
C
L
Q
K
K
K
Site 54
T558
L
A
A
E
Q
K
K
T
D
F
K
P
E
D
E
Site 55
Y615
V
R
F
H
R
L
I
Y
E
H
L
Q
Q
Y
S
Site 56
Y621
I
Y
E
H
L
Q
Q
Y
S
Y
S
C
M
G
G
Site 57
Y623
E
H
L
Q
Q
Y
S
Y
S
C
M
G
G
M
L
Site 58
S676
D
N
L
K
Q
V
C
S
G
E
Q
L
A
N
L
Site 59
S690
L
D
K
N
I
L
H
S
F
V
Q
L
R
A
D
Site 60
Y698
F
V
Q
L
R
A
D
Y
R
S
A
R
L
A
R
Site 61
S700
Q
L
R
A
D
Y
R
S
A
R
L
A
R
H
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation