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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLOD2
Full Name:
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Alias:
LH2; Lysyl hydroxylase 2; Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
Type:
Oxidoreductase; EC 1.14.11.4; Endoplasmic reticulum; Amino Acid Metabolism - lysine degradation
Mass (Da):
84690
Number AA:
UniProt ID:
O00469
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0031418
GO:0005506
GO:0016702
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0006464
GO:0001666
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
N
P
C
L
G
A
D
S
E
K
P
S
S
I
P
Site 2
S32
G
A
D
S
E
K
P
S
S
I
P
T
D
K
L
Site 3
S33
A
D
S
E
K
P
S
S
I
P
T
D
K
L
L
Site 4
T36
E
K
P
S
S
I
P
T
D
K
L
L
V
I
T
Site 5
T43
T
D
K
L
L
V
I
T
V
A
T
K
E
S
D
Site 6
Y61
R
F
M
Q
S
A
K
Y
F
N
Y
T
V
K
V
Site 7
Y64
Q
S
A
K
Y
F
N
Y
T
V
K
V
L
G
Q
Site 8
T65
S
A
K
Y
F
N
Y
T
V
K
V
L
G
Q
G
Site 9
S83
R
G
G
D
G
I
N
S
I
G
G
G
Q
K
V
Site 10
Y154
D
K
R
L
A
D
K
Y
P
V
V
H
I
G
K
Site 11
Y163
V
V
H
I
G
K
R
Y
L
N
S
G
G
F
I
Site 12
S166
I
G
K
R
Y
L
N
S
G
G
F
I
G
Y
A
Site 13
Y172
N
S
G
G
F
I
G
Y
A
P
Y
V
N
R
I
Site 14
Y199
Q
L
F
Y
T
K
V
Y
I
D
P
L
K
R
E
Site 15
T243
G
K
A
R
A
K
N
T
F
Y
E
T
L
P
V
Site 16
Y264
P
T
K
I
L
L
N
Y
F
G
N
Y
V
P
N
Site 17
Y268
L
L
N
Y
F
G
N
Y
V
P
N
S
W
T
Q
Site 18
S290
E
F
D
T
V
D
L
S
A
V
D
V
H
P
N
Site 19
T320
R
F
L
D
I
L
L
T
L
D
Y
P
K
E
A
Site 20
Y323
D
I
L
L
T
L
D
Y
P
K
E
A
L
K
L
Site 21
S367
V
G
P
E
E
N
L
S
Q
A
E
A
R
N
M
Site 22
Y387
R
Q
D
E
K
C
D
Y
Y
F
S
V
D
A
D
Site 23
Y388
Q
D
E
K
C
D
Y
Y
F
S
V
D
A
D
V
Site 24
S433
S
N
F
W
G
A
L
S
P
D
G
Y
Y
A
R
Site 25
Y437
G
A
L
S
P
D
G
Y
Y
A
R
S
E
D
Y
Site 26
Y438
A
L
S
P
D
G
Y
Y
A
R
S
E
D
Y
V
Site 27
Y444
Y
Y
A
R
S
E
D
Y
V
D
I
V
Q
G
N
Site 28
T471
V
Y
L
I
K
G
K
T
L
R
S
E
M
N
E
Site 29
S474
I
K
G
K
T
L
R
S
E
M
N
E
R
N
Y
Site 30
Y481
S
E
M
N
E
R
N
Y
F
V
R
D
K
L
D
Site 31
Y505
R
E
M
G
V
F
M
Y
I
S
N
R
H
E
F
Site 32
S517
H
E
F
G
R
L
L
S
T
A
N
Y
N
T
S
Site 33
Y521
R
L
L
S
T
A
N
Y
N
T
S
H
Y
N
N
Site 34
Y544
P
V
D
W
K
E
K
Y
I
N
R
D
Y
S
K
Site 35
Y549
E
K
Y
I
N
R
D
Y
S
K
I
F
T
E
N
Site 36
T554
R
D
Y
S
K
I
F
T
E
N
I
V
E
Q
P
Site 37
Y586
L
V
E
E
M
E
H
Y
G
K
W
S
G
G
K
Site 38
S597
S
G
G
K
H
H
D
S
R
I
S
G
G
Y
E
Site 39
S600
K
H
H
D
S
R
I
S
G
G
Y
E
N
V
P
Site 40
Y603
D
S
R
I
S
G
G
Y
E
N
V
P
T
D
D
Site 41
T608
G
G
Y
E
N
V
P
T
D
D
I
H
M
K
Q
Site 42
S656
L
N
F
V
V
K
Y
S
P
E
R
Q
R
S
L
Site 43
S662
Y
S
P
E
R
Q
R
S
L
R
P
H
H
D
A
Site 44
T671
R
P
H
H
D
A
S
T
F
T
I
N
I
A
L
Site 45
Y695
G
G
C
K
F
L
R
Y
N
C
S
I
E
S
P
Site 46
S698
K
F
L
R
Y
N
C
S
I
E
S
P
R
K
G
Site 47
S701
R
Y
N
C
S
I
E
S
P
R
K
G
W
S
F
Site 48
S707
E
S
P
R
K
G
W
S
F
M
H
P
G
R
L
Site 49
T715
F
M
H
P
G
R
L
T
H
L
H
E
G
L
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation