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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SAP18
Full Name:
Histone deacetylase complex subunit SAP18
Alias:
2hor0202; Cell growth inhibiting protein 38; Cell growth-inhibiting protein 38; Histone deacetylase complex subunit sap18; Sap18; Sap18p; Sin3 associated polypeptide; Sin3 associated polypeptide p18; Sin3a-associated protein, 18kda; Sin3-associated polypeptide p18; Sin3-associated polypeptide, 18 kda
Type:
Enzyme - Deacetylase
Mass (Da):
17561
Number AA:
153
UniProt ID:
O00422
International Prot ID:
IPI00011698
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0000118
Uniprot
OncoNet
Molecular Function:
GO:0003714
PhosphoSite+
KinaseNET
Biological Process:
GO:0006357
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
V
E
S
R
V
T
Q
E
E
I
K
K
E
Site 2
T25
K
P
I
D
R
E
K
T
C
P
L
L
L
R
V
Site 3
T34
P
L
L
L
R
V
F
T
T
N
N
G
R
H
H
Site 4
T35
L
L
L
R
V
F
T
T
N
N
G
R
H
H
R
Site 5
S47
H
H
R
M
D
E
F
S
R
G
N
V
P
S
S
Site 6
S53
F
S
R
G
N
V
P
S
S
E
L
Q
I
Y
T
Site 7
S54
S
R
G
N
V
P
S
S
E
L
Q
I
Y
T
W
Site 8
Y59
P
S
S
E
L
Q
I
Y
T
W
M
D
A
T
L
Site 9
Y77
T
S
L
V
K
E
V
Y
P
E
A
R
K
K
G
Site 10
T85
P
E
A
R
K
K
G
T
H
F
N
F
A
I
V
Site 11
T94
F
N
F
A
I
V
F
T
D
V
K
R
P
G
Y
Site 12
Y101
T
D
V
K
R
P
G
Y
R
V
K
E
I
G
S
Site 13
S108
Y
R
V
K
E
I
G
S
T
M
S
G
R
K
G
Site 14
T109
R
V
K
E
I
G
S
T
M
S
G
R
K
G
T
Site 15
S111
K
E
I
G
S
T
M
S
G
R
K
G
T
D
D
Site 16
T116
T
M
S
G
R
K
G
T
D
D
S
M
T
L
Q
Site 17
S119
G
R
K
G
T
D
D
S
M
T
L
Q
S
Q
K
Site 18
T121
K
G
T
D
D
S
M
T
L
Q
S
Q
K
F
Q
Site 19
S124
D
D
S
M
T
L
Q
S
Q
K
F
Q
I
G
D
Site 20
Y132
Q
K
F
Q
I
G
D
Y
L
D
I
A
I
T
P
Site 21
T138
D
Y
L
D
I
A
I
T
P
P
N
R
A
P
P
Site 22
S147
P
N
R
A
P
P
P
S
G
R
M
R
P
Y
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation