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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MATN2
Full Name:
Matrilin-2
Alias:
Matrilin 2
Type:
Extracellular matrix
Mass (Da):
106838
Number AA:
956
UniProt ID:
O00339
International Prot ID:
IPI00473118
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
P
A
E
A
R
E
R
S
R
G
R
S
I
S
R
Site 2
S31
R
E
R
S
R
G
R
S
I
S
R
G
R
H
A
Site 3
S33
R
S
R
G
R
S
I
S
R
G
R
H
A
R
T
Site 4
T44
H
A
R
T
H
P
Q
T
A
L
L
E
S
S
C
Site 5
S64
D
L
V
F
I
I
D
S
S
R
S
V
N
T
H
Site 6
S65
L
V
F
I
I
D
S
S
R
S
V
N
T
H
D
Site 7
Y73
R
S
V
N
T
H
D
Y
A
K
V
K
E
F
I
Site 8
Y101
T
R
V
G
L
L
Q
Y
G
S
T
V
K
N
E
Site 9
S103
V
G
L
L
Q
Y
G
S
T
V
K
N
E
F
S
Site 10
S110
S
T
V
K
N
E
F
S
L
K
T
F
K
R
K
Site 11
T113
K
N
E
F
S
L
K
T
F
K
R
K
S
E
V
Site 12
S118
L
K
T
F
K
R
K
S
E
V
E
R
A
V
K
Site 13
S131
V
K
R
M
R
H
L
S
T
G
T
M
T
G
L
Site 14
S149
Y
A
L
N
I
A
F
S
E
A
E
G
A
R
P
Site 15
S176
T
D
G
R
P
Q
D
S
V
A
E
V
A
A
K
Site 16
T203
V
G
Q
V
D
F
N
T
L
K
S
I
G
S
E
Site 17
S206
V
D
F
N
T
L
K
S
I
G
S
E
P
H
E
Site 18
S209
N
T
L
K
S
I
G
S
E
P
H
E
D
H
V
Site 19
T227
A
N
F
S
Q
I
E
T
L
T
S
V
F
Q
K
Site 20
S230
S
Q
I
E
T
L
T
S
V
F
Q
K
K
L
C
Site 21
Y260
C
I
N
I
P
G
S
Y
V
C
R
C
K
Q
G
Site 22
Y268
V
C
R
C
K
Q
G
Y
I
L
N
S
D
Q
T
Site 23
T275
Y
I
L
N
S
D
Q
T
T
C
R
I
Q
D
L
Site 24
T276
I
L
N
S
D
Q
T
T
C
R
I
Q
D
L
C
Site 25
Y323
K
R
C
V
A
V
D
Y
C
A
S
E
N
H
G
Site 26
Y342
C
V
N
A
D
G
S
Y
L
C
Q
C
H
E
G
Site 27
T358
A
L
N
P
D
E
K
T
C
T
K
I
D
Y
C
Site 28
Y364
K
T
C
T
K
I
D
Y
C
A
S
S
N
H
G
Site 29
Y383
C
V
N
T
D
D
S
Y
S
C
H
C
L
K
G
Site 30
T399
T
L
N
P
D
K
K
T
C
R
R
I
N
Y
C
Site 31
Y405
K
T
C
R
R
I
N
Y
C
A
L
N
K
P
G
Site 32
Y425
V
N
M
E
E
S
Y
Y
C
R
C
H
R
G
Y
Site 33
Y432
Y
C
R
C
H
R
G
Y
T
L
D
P
N
G
K
Site 34
T433
C
R
C
H
R
G
Y
T
L
D
P
N
G
K
T
Site 35
T440
T
L
D
P
N
G
K
T
C
S
R
V
D
H
C
Site 36
T481
L
I
N
E
D
L
K
T
C
S
R
V
D
Y
C
Site 37
Y487
K
T
C
S
R
V
D
Y
C
L
L
S
D
H
G
Site 38
Y497
L
S
D
H
G
C
E
Y
S
C
V
N
M
D
R
Site 39
S518
P
E
G
H
V
L
R
S
D
G
K
T
C
A
K
Site 40
T522
V
L
R
S
D
G
K
T
C
A
K
L
D
S
C
Site 41
S528
K
T
C
A
K
L
D
S
C
A
L
G
D
H
G
Site 42
S539
G
D
H
G
C
E
H
S
C
V
S
S
E
D
S
Site 43
S542
G
C
E
H
S
C
V
S
S
E
D
S
F
V
C
Site 44
Y555
V
C
Q
C
F
E
G
Y
I
L
R
E
D
G
K
Site 45
T563
I
L
R
E
D
G
K
T
C
R
R
K
D
V
C
Site 46
Y588
C
V
N
S
D
D
S
Y
T
C
E
C
L
E
G
Site 47
T589
V
N
S
D
D
S
Y
T
C
E
C
L
E
G
F
Site 48
Y629
C
V
N
N
G
N
S
Y
I
C
K
C
S
E
G
Site 49
T650
G
R
R
C
K
K
C
T
E
G
P
I
D
L
V
Site 50
S665
F
V
I
D
G
S
K
S
L
G
E
E
N
F
E
Site 51
S700
R
V
G
L
L
Q
Y
S
T
Q
V
H
T
E
F
Site 52
T701
V
G
L
L
Q
Y
S
T
Q
V
H
T
E
F
T
Site 53
T705
Q
Y
S
T
Q
V
H
T
E
F
T
L
R
N
F
Site 54
T708
T
Q
V
H
T
E
F
T
L
R
N
F
N
S
A
Site 55
S714
F
T
L
R
N
F
N
S
A
K
D
M
K
K
A
Site 56
Y727
K
A
V
A
H
M
K
Y
M
G
K
G
S
M
T
Site 57
S745
L
K
H
M
F
E
R
S
F
T
Q
G
E
G
A
Site 58
T747
H
M
F
E
R
S
F
T
Q
G
E
G
A
R
P
Site 59
S756
G
E
G
A
R
P
L
S
T
R
V
P
R
A
A
Site 60
S776
G
R
A
Q
D
D
V
S
E
W
A
S
K
A
K
Site 61
S780
D
D
V
S
E
W
A
S
K
A
K
A
N
G
I
Site 62
S807
E
E
L
Q
E
I
A
S
E
P
T
N
K
H
L
Site 63
Y816
P
T
N
K
H
L
F
Y
A
E
D
F
S
T
M
Site 64
S821
L
F
Y
A
E
D
F
S
T
M
D
E
I
S
E
Site 65
T822
F
Y
A
E
D
F
S
T
M
D
E
I
S
E
K
Site 66
S841
I
C
E
A
L
E
D
S
D
G
R
Q
D
S
P
Site 67
S847
D
S
D
G
R
Q
D
S
P
A
G
E
L
P
K
Site 68
T855
P
A
G
E
L
P
K
T
V
Q
Q
P
T
E
S
Site 69
T866
P
T
E
S
E
P
V
T
I
N
I
Q
D
L
L
Site 70
S894
E
E
D
N
L
L
R
S
T
Q
K
L
S
H
S
Site 71
T895
E
D
N
L
L
R
S
T
Q
K
L
S
H
S
T
Site 72
S899
L
R
S
T
Q
K
L
S
H
S
T
K
P
S
G
Site 73
S901
S
T
Q
K
L
S
H
S
T
K
P
S
G
S
P
Site 74
S905
L
S
H
S
T
K
P
S
G
S
P
L
E
E
K
Site 75
S907
H
S
T
K
P
S
G
S
P
L
E
E
K
H
D
Site 76
T936
N
E
E
V
R
K
L
T
Q
R
L
E
E
M
T
Site 77
T943
T
Q
R
L
E
E
M
T
Q
R
M
E
A
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation