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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAF4
Full Name:
Transcription initiation factor TFIID subunit 4
Alias:
TBP-associated factor 4
Type:
Mass (Da):
110096
Number AA:
1085
UniProt ID:
O00268
International Prot ID:
IPI00413755
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005667
GO:0005669
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0001541
GO:0006139
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
E
V
D
E
K
V
V
S
D
L
V
G
S
L
E
Site 2
S36
L
E
S
Q
L
A
A
S
A
A
H
H
H
H
L
Site 3
T47
H
H
H
L
A
P
R
T
P
E
V
R
A
A
A
Site 4
S109
P
Q
R
P
G
P
P
S
P
R
R
P
L
V
P
Site 5
S133
L
R
P
P
P
E
G
S
A
G
S
C
A
P
V
Site 6
S136
P
P
E
G
S
A
G
S
C
A
P
V
P
A
A
Site 7
T236
P
K
P
A
A
P
G
T
V
I
Q
T
P
P
F
Site 8
S256
P
P
A
P
A
A
P
S
P
P
A
A
P
A
P
Site 9
T279
P
P
P
P
A
P
A
T
L
A
R
P
P
G
H
Site 10
T292
G
H
P
A
G
P
P
T
A
A
P
A
V
P
P
Site 11
S326
A
G
G
P
A
G
V
S
G
Q
P
G
P
G
A
Site 12
S346
A
P
G
V
K
A
E
S
P
K
R
V
V
Q
A
Site 13
T396
V
P
P
P
A
P
G
T
P
T
G
L
P
K
G
Site 14
T398
P
P
A
P
G
T
P
T
G
L
P
K
G
A
A
Site 15
T409
K
G
A
A
G
A
V
T
Q
S
L
S
R
T
P
Site 16
S411
A
A
G
A
V
T
Q
S
L
S
R
T
P
T
A
Site 17
S413
G
A
V
T
Q
S
L
S
R
T
P
T
A
T
T
Site 18
T415
V
T
Q
S
L
S
R
T
P
T
A
T
T
S
G
Site 19
T417
Q
S
L
S
R
T
P
T
A
T
T
S
G
I
R
Site 20
T419
L
S
R
T
P
T
A
T
T
S
G
I
R
A
T
Site 21
T487
A
H
A
Q
P
Q
T
T
M
A
P
R
P
A
T
Site 22
T494
T
M
A
P
R
P
A
T
P
T
S
A
P
P
V
Site 23
T496
A
P
R
P
A
T
P
T
S
A
P
P
V
Q
I
Site 24
S497
P
R
P
A
T
P
T
S
A
P
P
V
Q
I
S
Site 25
S504
S
A
P
P
V
Q
I
S
T
V
Q
A
P
G
T
Site 26
T505
A
P
P
V
Q
I
S
T
V
Q
A
P
G
T
P
Site 27
S528
T
T
I
I
K
Q
V
S
Q
A
Q
T
T
V
Q
Site 28
T532
K
Q
V
S
Q
A
Q
T
T
V
Q
P
S
A
T
Site 29
T533
Q
V
S
Q
A
Q
T
T
V
Q
P
S
A
T
L
Site 30
T539
T
T
V
Q
P
S
A
T
L
Q
R
S
P
G
V
Site 31
S543
P
S
A
T
L
Q
R
S
P
G
V
Q
P
Q
L
Site 32
T571
A
T
A
V
Q
T
G
T
P
Q
R
T
V
P
G
Site 33
T575
Q
T
G
T
P
Q
R
T
V
P
G
A
T
T
T
Site 34
S584
P
G
A
T
T
T
S
S
A
A
T
E
T
M
E
Site 35
S601
K
K
C
K
N
F
L
S
T
L
I
K
L
A
S
Site 36
S608
S
T
L
I
K
L
A
S
S
G
K
Q
S
T
E
Site 37
S609
T
L
I
K
L
A
S
S
G
K
Q
S
T
E
T
Site 38
S613
L
A
S
S
G
K
Q
S
T
E
T
A
A
N
V
Site 39
T638
K
I
E
A
E
D
F
T
S
R
L
Y
R
E
L
Site 40
Y642
E
D
F
T
S
R
L
Y
R
E
L
N
S
S
P
Site 41
S648
L
Y
R
E
L
N
S
S
P
Q
P
Y
L
V
P
Site 42
Y652
L
N
S
S
P
Q
P
Y
L
V
P
F
L
K
R
Site 43
S671
L
R
Q
L
T
P
D
S
A
A
F
I
Q
Q
S
Site 44
S678
S
A
A
F
I
Q
Q
S
Q
Q
Q
P
P
P
P
Site 45
S687
Q
Q
P
P
P
P
T
S
Q
A
T
T
A
L
T
Site 46
T705
L
S
S
S
V
Q
R
T
A
G
K
T
A
A
T
Site 47
T709
V
Q
R
T
A
G
K
T
A
A
T
V
T
S
A
Site 48
T739
V
G
K
Q
G
Q
P
T
P
L
V
I
Q
Q
P
Site 49
T763
P
Q
V
T
L
T
Q
T
P
M
V
A
L
R
Q
Site 50
T779
H
N
R
I
M
L
T
T
P
Q
Q
I
Q
L
N
Site 51
S827
L
K
E
P
G
G
G
S
F
R
D
D
D
D
I
Site 52
S857
A
R
I
L
A
T
N
S
E
L
V
G
T
L
T
Site 53
T862
T
N
S
E
L
V
G
T
L
T
R
S
C
K
D
Site 54
T864
S
E
L
V
G
T
L
T
R
S
C
K
D
E
T
Site 55
T871
T
R
S
C
K
D
E
T
F
L
L
Q
A
P
L
Site 56
S900
E
L
H
P
D
V
V
S
Y
V
S
H
A
T
Q
Site 57
Y901
L
H
P
D
V
V
S
Y
V
S
H
A
T
Q
Q
Site 58
Y934
S
Y
K
D
D
D
R
Y
E
Q
A
S
D
V
R
Site 59
S938
D
D
R
Y
E
Q
A
S
D
V
R
A
Q
L
K
Site 60
S972
I
L
M
R
A
A
K
S
R
S
R
Q
E
D
P
Site 61
T1007
R
Q
R
D
A
N
L
T
A
L
A
A
I
G
P
Site 62
S1027
V
D
C
P
G
P
G
S
G
A
E
G
S
G
P
Site 63
S1032
P
G
S
G
A
E
G
S
G
P
G
S
V
V
P
Site 64
S1036
A
E
G
S
G
P
G
S
V
V
P
G
S
S
G
Site 65
S1041
P
G
S
V
V
P
G
S
S
G
V
G
T
P
R
Site 66
S1042
G
S
V
V
P
G
S
S
G
V
G
T
P
R
Q
Site 67
T1046
P
G
S
S
G
V
G
T
P
R
Q
F
T
R
Q
Site 68
T1051
V
G
T
P
R
Q
F
T
R
Q
R
I
T
R
V
Site 69
T1056
Q
F
T
R
Q
R
I
T
R
V
N
L
R
D
L
Site 70
T1073
C
L
E
N
E
R
E
T
S
H
S
L
L
L
Y
Site 71
S1074
L
E
N
E
R
E
T
S
H
S
L
L
L
Y
K
Site 72
S1076
N
E
R
E
T
S
H
S
L
L
L
Y
K
A
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation