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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIF2
Full Name:
Kinesin-like protein KIF2A
Alias:
HK2; Kinesin heavy chain member 2A; Kinesin-2; Kinesin-like protein KIF2; KNS2
Type:
Microtubule binding protein; Motor protein
Mass (Da):
79955
Number AA:
706
UniProt ID:
O00139
International Prot ID:
IPI00010368
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007018
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
G
K
I
Q
I
G
I
Y
V
E
I
K
R
S
D
Site 2
S20
I
Y
V
E
I
K
R
S
D
G
R
I
H
Q
A
Site 3
S38
S
L
N
E
D
N
E
S
V
T
V
E
W
I
E
Site 4
T40
N
E
D
N
E
S
V
T
V
E
W
I
E
N
G
Site 5
T49
E
W
I
E
N
G
D
T
K
G
K
E
I
D
L
Site 6
S58
G
K
E
I
D
L
E
S
I
F
S
L
N
P
D
Site 7
S75
P
D
E
E
I
E
P
S
P
E
T
P
P
P
P
Site 8
T78
E
I
E
P
S
P
E
T
P
P
P
P
A
S
S
Site 9
S84
E
T
P
P
P
P
A
S
S
A
K
V
N
K
I
Site 10
S85
T
P
P
P
P
A
S
S
A
K
V
N
K
I
V
Site 11
T97
K
I
V
K
N
R
R
T
V
A
S
I
K
N
D
Site 12
S100
K
N
R
R
T
V
A
S
I
K
N
D
P
P
S
Site 13
S107
S
I
K
N
D
P
P
S
R
D
N
R
V
V
G
Site 14
S115
R
D
N
R
V
V
G
S
A
R
A
R
P
S
Q
Site 15
S121
G
S
A
R
A
R
P
S
Q
F
P
E
Q
S
S
Site 16
S127
P
S
Q
F
P
E
Q
S
S
S
A
Q
Q
N
G
Site 17
S129
Q
F
P
E
Q
S
S
S
A
Q
Q
N
G
S
V
Site 18
S135
S
S
A
Q
Q
N
G
S
V
S
D
I
S
P
V
Site 19
S137
A
Q
Q
N
G
S
V
S
D
I
S
P
V
Q
A
Site 20
S140
N
G
S
V
S
D
I
S
P
V
Q
A
A
K
K
Site 21
S153
K
K
E
F
G
P
P
S
R
R
K
S
N
C
V
Site 22
S157
G
P
P
S
R
R
K
S
N
C
V
K
E
V
E
Site 23
T191
R
A
Q
D
V
D
A
T
N
P
N
Y
E
I
M
Site 24
Y195
V
D
A
T
N
P
N
Y
E
I
M
C
M
I
R
Site 25
S207
M
I
R
D
F
R
G
S
L
D
Y
R
P
L
T
Site 26
Y210
D
F
R
G
S
L
D
Y
R
P
L
T
T
A
D
Site 27
T214
S
L
D
Y
R
P
L
T
T
A
D
P
I
D
E
Site 28
T266
P
K
Q
K
V
D
L
T
R
Y
L
E
N
Q
T
Site 29
Y268
Q
K
V
D
L
T
R
Y
L
E
N
Q
T
F
R
Site 30
T273
T
R
Y
L
E
N
Q
T
F
R
F
D
Y
A
F
Site 31
Y278
N
Q
T
F
R
F
D
Y
A
F
D
D
S
A
P
Site 32
T293
N
E
M
V
Y
R
F
T
A
R
P
L
V
E
T
Site 33
Y312
G
M
A
T
C
F
A
Y
G
Q
T
G
S
G
K
Site 34
T322
T
G
S
G
K
T
H
T
M
G
G
D
F
S
G
Site 35
S335
S
G
K
N
Q
D
C
S
K
G
I
Y
A
L
A
Site 36
Y355
L
M
L
K
K
P
N
Y
K
K
L
E
L
Q
V
Site 37
T382
F
D
L
L
N
R
K
T
K
L
R
V
L
E
D
Site 38
S419
K
L
I
D
I
G
N
S
C
R
T
S
G
Q
T
Site 39
S423
I
G
N
S
C
R
T
S
G
Q
T
S
A
N
A
Site 40
T426
S
C
R
T
S
G
Q
T
S
A
N
A
H
S
S
Site 41
S427
C
R
T
S
G
Q
T
S
A
N
A
H
S
S
R
Site 42
S432
Q
T
S
A
N
A
H
S
S
R
S
H
A
V
F
Site 43
S433
T
S
A
N
A
H
S
S
R
S
H
A
V
F
Q
Site 44
S454
G
K
L
H
G
K
F
S
L
I
D
L
A
G
N
Site 45
S468
N
E
R
G
A
D
T
S
S
A
D
R
Q
T
R
Site 46
S469
E
R
G
A
D
T
S
S
A
D
R
Q
T
R
L
Site 47
T474
T
S
S
A
D
R
Q
T
R
L
E
G
A
E
I
Site 48
S484
E
G
A
E
I
N
K
S
L
L
A
L
K
E
C
Site 49
T502
L
G
R
N
K
P
H
T
P
F
R
A
S
K
L
Site 50
S507
P
H
T
P
F
R
A
S
K
L
T
Q
V
L
R
Site 51
T510
P
F
R
A
S
K
L
T
Q
V
L
R
D
S
F
Site 52
S516
L
T
Q
V
L
R
D
S
F
I
G
E
N
S
R
Site 53
T540
G
M
A
S
C
E
N
T
L
N
T
L
R
Y
A
Site 54
Y546
N
T
L
N
T
L
R
Y
A
N
R
V
K
E
L
Site 55
T554
A
N
R
V
K
E
L
T
V
D
P
T
A
A
G
Site 56
T579
N
Q
I
D
D
L
E
T
Q
W
G
V
G
S
S
Site 57
S586
T
Q
W
G
V
G
S
S
P
Q
R
D
D
L
K
Site 58
S604
E
Q
N
E
E
E
V
S
P
Q
L
F
T
F
H
Site 59
T609
E
V
S
P
Q
L
F
T
F
H
E
A
V
S
Q
Site 60
S615
F
T
F
H
E
A
V
S
Q
M
V
E
M
E
E
Site 61
S635
H
R
A
V
F
Q
E
S
I
R
W
L
E
D
E
Site 62
Y654
E
M
T
E
E
V
D
Y
D
V
D
S
Y
A
T
Site 63
S658
E
V
D
Y
D
V
D
S
Y
A
T
Q
L
E
A
Site 64
Y659
V
D
Y
D
V
D
S
Y
A
T
Q
L
E
A
I
Site 65
T675
E
Q
K
I
D
I
L
T
E
L
R
D
K
V
K
Site 66
S683
E
L
R
D
K
V
K
S
F
R
A
A
L
Q
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation