PhosphoNET

           
Protein Info 
   
Short Name:  DNASE2
Full Name:  Deoxyribonuclease-2-alpha
Alias:  Acid DNase;Deoxyribonuclease II alpha;Lysosomal DNase II;R31240_2
Type: 
Mass (Da):  39581
Number AA:  360
UniProt ID:  O00115
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y20PAGALTCYGDSGQPV
Site 2S41KLPALRGSGEAAQRG
Site 3Y53QRGLQYKYLDESSGG
Site 4S57QYKYLDESSGGWRDG
Site 5S70DGRALINSPEGAVGR
Site 6Y83GRSLQPLYRSNTSQL
Site 7S85SLQPLYRSNTSQLAF
Site 8T87QPLYRSNTSQLAFLL
Site 9S88PLYRSNTSQLAFLLY
Site 10Y95SQLAFLLYNDQPPQP
Site 11S103NDQPPQPSKAQDSSM
Site 12S108QPSKAQDSSMRGHTK
Site 13S109PSKAQDSSMRGHTKG
Site 14T114DSSMRGHTKGVLLLD
Site 15S140PNFPPPASSAAYSWP
Site 16S141NFPPPASSAAYSWPH
Site 17Y144PPASSAAYSWPHSAC
Site 18S145PASSAAYSWPHSACT
Site 19S168SFPFAQFSKMGKQLT
Site 20T175SKMGKQLTYTYPWVY
Site 21Y176KMGKQLTYTYPWVYN
Site 22Y178GKQLTYTYPWVYNYQ
Site 23Y184TYPWVYNYQLEGIFA
Site 24S207VVKGHHVSQEPWNSS
Site 25S213VSQEPWNSSITLTSQ
Site 26Y239SKFGDDLYSGWLAAA
Site 27S288FPGPAGPSFNSTEDH
Site 28S291PAGPSFNSTEDHSKW
Site 29T292AGPSFNSTEDHSKWC
Site 30T307VSPKGPWTCVGDMNR
Site 31Y344FQPLVKNYQPCNGMA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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