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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RSPH10B2
Full Name:
Radial spoke head 10 homolog B2
Alias:
Type:
Mass (Da):
100547
Number AA:
870
UniProt ID:
B2RC85
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
A
D
K
K
G
E
K
S
A
R
S
P
S
S
L
Site 2
S18
K
G
E
K
S
A
R
S
P
S
S
L
S
D
N
Site 3
S20
E
K
S
A
R
S
P
S
S
L
S
D
N
L
D
Site 4
S21
K
S
A
R
S
P
S
S
L
S
D
N
L
D
F
Site 5
S23
A
R
S
P
S
S
L
S
D
N
L
D
F
S
K
Site 6
S29
L
S
D
N
L
D
F
S
K
Q
D
G
N
T
T
Site 7
T35
F
S
K
Q
D
G
N
T
T
R
Q
E
M
S
P
Site 8
S41
N
T
T
R
Q
E
M
S
P
A
G
V
P
L
L
Site 9
S71
V
Q
Q
N
E
D
A
S
Q
Y
E
E
S
I
L
Site 10
Y73
Q
N
E
D
A
S
Q
Y
E
E
S
I
L
T
K
Site 11
S76
D
A
S
Q
Y
E
E
S
I
L
T
K
L
I
V
Site 12
T79
Q
Y
E
E
S
I
L
T
K
L
I
V
E
S
Y
Site 13
Y95
G
E
K
V
R
G
L
Y
E
G
E
G
F
A
A
Site 14
Y109
A
F
Q
G
G
C
T
Y
R
G
M
F
S
E
G
Site 15
Y124
L
M
H
G
Q
G
T
Y
I
W
A
D
G
L
K
Site 16
Y132
I
W
A
D
G
L
K
Y
E
G
D
F
V
K
N
Site 17
Y147
V
P
M
N
H
G
V
Y
T
W
P
D
G
S
M
Site 18
Y155
T
W
P
D
G
S
M
Y
E
G
E
V
V
N
G
Site 19
S193
G
K
R
H
G
K
G
S
I
Y
Y
N
Q
E
G
Site 20
Y195
R
H
G
K
G
S
I
Y
Y
N
Q
E
G
T
C
Site 21
Y221
K
G
W
G
I
R
C
Y
K
S
G
N
I
Y
E
Site 22
Y227
C
Y
K
S
G
N
I
Y
E
G
Q
W
E
D
N
Site 23
T246
E
G
R
M
R
W
L
T
T
N
E
E
Y
T
G
Site 24
T265
G
I
Q
N
G
F
G
T
H
T
W
F
L
K
R
Site 25
S275
W
F
L
K
R
I
R
S
S
Q
Y
P
L
R
N
Site 26
S276
F
L
K
R
I
R
S
S
Q
Y
P
L
R
N
E
Site 27
Y278
K
R
I
R
S
S
Q
Y
P
L
R
N
E
Y
I
Site 28
Y284
Q
Y
P
L
R
N
E
Y
I
G
E
F
V
N
G
Site 29
Y292
I
G
E
F
V
N
G
Y
R
H
G
R
G
K
F
Site 30
Y300
R
H
G
R
G
K
F
Y
Y
A
S
G
A
M
Y
Site 31
Y301
H
G
R
G
K
F
Y
Y
A
S
G
A
M
Y
D
Site 32
S303
R
G
K
F
Y
Y
A
S
G
A
M
Y
D
G
E
Site 33
Y307
Y
Y
A
S
G
A
M
Y
D
G
E
W
V
S
N
Site 34
T323
K
H
G
M
G
R
L
T
F
K
N
G
R
V
Y
Site 35
Y330
T
F
K
N
G
R
V
Y
E
G
A
F
S
N
D
Site 36
S335
R
V
Y
E
G
A
F
S
N
D
H
I
A
G
F
Site 37
S364
S
G
V
A
P
R
L
S
R
S
A
E
L
I
R
Site 38
S376
L
I
R
K
L
D
G
S
E
S
H
S
V
L
G
Site 39
S378
R
K
L
D
G
S
E
S
H
S
V
L
G
S
S
Site 40
S380
L
D
G
S
E
S
H
S
V
L
G
S
S
I
E
Site 41
S384
E
S
H
S
V
L
G
S
S
I
E
L
D
L
N
Site 42
Y397
L
N
L
L
L
D
M
Y
P
E
T
V
Q
P
E
Site 43
T400
L
L
D
M
Y
P
E
T
V
Q
P
E
E
K
K
Site 44
T418
Y
A
V
L
R
N
I
T
E
L
R
R
I
Y
S
Site 45
Y424
I
T
E
L
R
R
I
Y
S
F
Y
S
S
L
G
Site 46
S425
T
E
L
R
R
I
Y
S
F
Y
S
S
L
G
C
Site 47
Y427
L
R
R
I
Y
S
F
Y
S
S
L
G
C
G
H
Site 48
S428
R
R
I
Y
S
F
Y
S
S
L
G
C
G
H
S
Site 49
S429
R
I
Y
S
F
Y
S
S
L
G
C
G
H
S
L
Site 50
T439
C
G
H
S
L
D
N
T
F
L
M
T
K
L
H
Site 51
T462
K
F
H
H
H
K
L
T
L
A
D
M
D
R
I
Site 52
S471
A
D
M
D
R
I
L
S
A
N
N
D
I
P
V
Site 53
Y505
L
H
L
A
Y
H
I
Y
H
E
E
F
Q
K
R
Site 54
S513
H
E
E
F
Q
K
R
S
P
S
L
F
L
C
F
Site 55
S515
E
F
Q
K
R
S
P
S
L
F
L
C
F
T
K
Site 56
T546
L
F
R
E
Q
Q
R
T
L
Y
S
M
S
Y
M
Site 57
Y548
R
E
Q
Q
R
T
L
Y
S
M
S
Y
M
N
K
Site 58
S567
Y
L
A
Y
C
R
P
S
A
A
P
P
H
E
P
Site 59
Y612
A
E
D
N
R
F
I
Y
D
G
I
D
S
N
F
Site 60
S617
F
I
Y
D
G
I
D
S
N
F
E
P
E
L
V
Site 61
S647
V
T
D
Q
M
T
K
S
Y
T
N
V
P
A
D
Site 62
S657
N
V
P
A
D
D
V
S
G
N
K
H
E
T
I
Site 63
T666
N
K
H
E
T
I
Y
T
I
L
N
Q
D
A
Q
Site 64
S676
N
Q
D
A
Q
N
K
S
P
S
A
V
M
S
H
Site 65
S678
D
A
Q
N
K
S
P
S
A
V
M
S
H
E
S
Site 66
S682
K
S
P
S
A
V
M
S
H
E
S
D
A
A
H
Site 67
S685
S
A
V
M
S
H
E
S
D
A
A
H
S
D
S
Site 68
S690
H
E
S
D
A
A
H
S
D
S
A
R
S
S
S
Site 69
S692
S
D
A
A
H
S
D
S
A
R
S
S
S
S
K
Site 70
S695
A
H
S
D
S
A
R
S
S
S
S
K
L
E
L
Site 71
S696
H
S
D
S
A
R
S
S
S
S
K
L
E
L
S
Site 72
S697
S
D
S
A
R
S
S
S
S
K
L
E
L
S
P
Site 73
S698
D
S
A
R
S
S
S
S
K
L
E
L
S
P
D
Site 74
S703
S
S
S
K
L
E
L
S
P
D
V
N
K
I
R
Site 75
S712
D
V
N
K
I
R
K
S
E
P
K
I
K
K
S
Site 76
S719
S
E
P
K
I
K
K
S
V
S
H
E
R
V
S
Site 77
S721
P
K
I
K
K
S
V
S
H
E
R
V
S
K
M
Site 78
S726
S
V
S
H
E
R
V
S
K
M
N
F
K
L
T
Site 79
T733
S
K
M
N
F
K
L
T
G
K
G
I
T
F
F
Site 80
T738
K
L
T
G
K
G
I
T
F
F
S
S
E
S
K
Site 81
S741
G
K
G
I
T
F
F
S
S
E
S
K
K
Y
E
Site 82
S742
K
G
I
T
F
F
S
S
E
S
K
K
Y
E
R
Site 83
Y747
F
S
S
E
S
K
K
Y
E
R
P
K
D
D
R
Site 84
S794
I
R
A
D
R
L
R
S
T
A
Q
A
Q
Q
R
Site 85
T795
R
A
D
R
L
R
S
T
A
Q
A
Q
Q
R
K
Site 86
Y827
E
E
A
K
R
H
D
Y
E
V
D
I
T
V
L
Site 87
T832
H
D
Y
E
V
D
I
T
V
L
K
E
P
A
D
Site 88
S841
L
K
E
P
A
D
V
S
S
S
H
L
I
L
D
Site 89
T855
D
P
P
K
E
D
V
T
V
S
P
S
S
K
T
Site 90
S857
P
K
E
D
V
T
V
S
P
S
S
K
T
I
T
Site 91
S859
E
D
V
T
V
S
P
S
S
K
T
I
T
S
K
Site 92
S860
D
V
T
V
S
P
S
S
K
T
I
T
S
K
K
Site 93
T864
S
P
S
S
K
T
I
T
S
K
K
K
K
K
_
Site 94
S865
P
S
S
K
T
I
T
S
K
K
K
K
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation