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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FER1L4
Full Name:
Fer-1-like protein 4
Alias:
Type:
Mass (Da):
200980
Number AA:
1794
UniProt ID:
A9Z1Z3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
F
S
P
L
K
S
R
A
R
A
L
A
H
Site 2
T58
V
G
G
Q
R
R
V
T
A
T
Q
R
G
T
S
Site 3
T60
G
Q
R
R
V
T
A
T
Q
R
G
T
S
C
P
Site 4
T64
V
T
A
T
Q
R
G
T
S
C
P
F
Y
N
E
Site 5
Y69
R
G
T
S
C
P
F
Y
N
E
Y
F
L
F
E
Site 6
Y72
S
C
P
F
Y
N
E
Y
F
L
F
E
F
H
D
Site 7
T80
F
L
F
E
F
H
D
T
R
L
R
L
Q
D
L
Site 8
Y125
D
Q
P
D
G
Q
F
Y
Q
R
W
V
P
L
H
Site 9
T137
P
L
H
D
P
R
D
T
R
A
G
T
K
G
F
Site 10
T141
P
R
D
T
R
A
G
T
K
G
F
I
K
V
T
Site 11
S170
P
P
A
P
G
H
C
S
D
I
E
K
N
L
L
Site 12
Y196
A
R
L
R
V
R
L
Y
R
A
E
G
L
P
A
Site 13
S230
V
E
P
Y
V
R
V
S
F
L
G
Q
E
G
E
Site 14
S239
L
G
Q
E
G
E
T
S
V
S
A
E
A
A
A
Site 15
S254
P
E
W
N
E
Q
L
S
F
V
E
L
F
P
P
Site 16
S265
L
F
P
P
L
T
R
S
L
R
L
Q
L
R
D
Site 17
S292
V
P
D
L
R
R
I
S
H
P
G
R
A
A
G
Site 18
T303
R
A
A
G
F
N
P
T
F
G
P
A
W
V
P
Site 19
Y312
G
P
A
W
V
P
L
Y
G
S
P
P
G
A
G
Site 20
S323
P
G
A
G
L
R
D
S
L
Q
G
L
N
E
G
Site 21
S365
P
P
Q
A
Q
Q
G
S
T
L
S
R
L
T
R
Site 22
T366
P
Q
A
Q
Q
G
S
T
L
S
R
L
T
R
K
Site 23
T371
G
S
T
L
S
R
L
T
R
K
K
K
K
K
A
Site 24
T383
K
K
A
R
R
D
Q
T
P
K
A
V
P
Q
H
Site 25
S394
V
P
Q
H
L
D
A
S
P
G
A
E
G
P
E
Site 26
T442
E
A
T
M
I
D
P
T
V
A
S
Q
P
I
S
Site 27
S453
Q
P
I
S
F
E
I
S
I
G
R
A
G
R
L
Site 28
S468
E
E
Q
L
G
R
G
S
R
A
G
E
G
T
E
Site 29
T500
K
E
E
E
E
L
G
T
H
A
Q
R
P
E
P
Site 30
S511
R
P
E
P
M
D
G
S
G
P
Y
F
C
L
P
Site 31
T596
C
H
G
A
E
R
R
T
M
T
R
P
N
A
L
Site 32
T598
G
A
E
R
R
T
M
T
R
P
N
A
L
D
R
Site 33
S614
R
G
K
L
L
V
H
S
L
N
L
L
A
K
Q
Site 34
S686
P
A
Q
D
V
L
F
S
V
V
E
E
E
R
G
Site 35
S701
R
D
C
G
K
I
Q
S
L
M
L
T
A
P
G
Site 36
S746
P
D
L
L
P
E
P
S
A
G
L
P
S
S
L
Site 37
S752
P
S
A
G
L
P
S
S
L
H
R
D
D
F
S
Site 38
S759
S
L
H
R
D
D
F
S
Y
F
Q
L
R
A
H
Site 39
Y760
L
H
R
D
D
F
S
Y
F
Q
L
R
A
H
L
Site 40
S782
A
A
D
D
S
G
L
S
D
P
F
A
R
V
L
Site 41
S791
P
F
A
R
V
L
I
S
T
Q
C
Q
T
T
R
Site 42
T803
T
T
R
V
L
E
Q
T
L
S
P
L
W
D
E
Site 43
S805
R
V
L
E
Q
T
L
S
P
L
W
D
E
L
L
Site 44
Y865
V
K
L
M
E
D
P
Y
Q
R
P
E
L
Q
F
Site 45
Y896
F
Q
L
I
E
L
D
Y
S
G
R
L
E
P
S
Site 46
S897
Q
L
I
E
L
D
Y
S
G
R
L
E
P
S
V
Site 47
S903
Y
S
G
R
L
E
P
S
V
P
S
E
V
E
P
Site 48
S921
A
P
L
V
E
P
H
S
G
R
L
S
L
P
P
Site 49
S925
E
P
H
S
G
R
L
S
L
P
P
N
V
C
P
Site 50
S973
V
A
G
Q
G
V
E
S
E
V
L
A
S
Y
R
Site 51
S978
V
E
S
E
V
L
A
S
Y
R
E
S
P
N
F
Site 52
S982
V
L
A
S
Y
R
E
S
P
N
F
T
E
L
V
Site 53
T986
Y
R
E
S
P
N
F
T
E
L
V
R
H
L
T
Site 54
T993
T
E
L
V
R
H
L
T
V
D
L
P
E
Q
P
Site 55
Y1001
V
D
L
P
E
Q
P
Y
L
Q
P
P
L
S
I
Site 56
T1019
E
R
R
A
F
G
H
T
V
L
V
G
S
H
I
Site 57
T1034
V
P
H
M
L
R
F
T
F
R
G
H
E
D
P
Site 58
T1051
E
E
G
E
M
E
E
T
G
D
M
M
P
K
G
Site 59
S1064
K
G
P
Q
G
Q
K
S
L
D
P
F
L
A
E
Site 60
Y1114
E
L
D
W
G
S
K
Y
Y
A
S
L
Q
E
L
Site 61
S1117
W
G
S
K
Y
Y
A
S
L
Q
E
L
Q
G
Q
Site 62
S1138
E
M
D
D
P
G
D
S
D
G
V
N
L
I
S
Site 63
T1161
G
E
A
E
V
K
G
T
V
S
P
K
K
A
V
Site 64
S1163
A
E
V
K
G
T
V
S
P
K
K
A
V
A
T
Site 65
Y1174
A
V
A
T
L
K
I
Y
N
R
S
L
K
E
E
Site 66
Y1195
W
L
N
V
F
P
L
Y
R
G
Q
G
G
Q
D
Site 67
S1210
G
G
G
E
E
E
G
S
G
H
L
V
G
K
F
Site 68
S1233
E
S
E
A
V
L
F
S
E
P
Q
I
S
R
G
Site 69
S1238
L
F
S
E
P
Q
I
S
R
G
I
P
Q
N
R
Site 70
Y1273
P
N
G
K
A
D
P
Y
V
V
V
S
A
G
R
Site 71
S1277
A
D
P
Y
V
V
V
S
A
G
R
E
R
Q
D
Site 72
T1285
A
G
R
E
R
Q
D
T
K
E
R
Y
I
P
K
Site 73
Y1289
R
Q
D
T
K
E
R
Y
I
P
K
Q
L
N
P
Site 74
Y1342
I
D
L
E
N
R
F
Y
S
H
H
R
A
N
C
Site 75
S1353
R
A
N
C
G
L
A
S
Q
Y
E
V
D
G
Y
Site 76
Y1355
N
C
G
L
A
S
Q
Y
E
V
D
G
Y
N
A
Site 77
Y1360
S
Q
Y
E
V
D
G
Y
N
A
W
R
D
A
F
Site 78
T1405
V
F
L
T
P
P
E
T
L
P
P
G
S
S
S
Site 79
S1410
P
E
T
L
P
P
G
S
S
S
P
T
V
A
S
Site 80
S1411
E
T
L
P
P
G
S
S
S
P
T
V
A
S
G
Site 81
S1412
T
L
P
P
G
S
S
S
P
T
V
A
S
G
D
Site 82
T1414
P
P
G
S
S
S
P
T
V
A
S
G
D
P
E
Site 83
S1417
S
S
S
P
T
V
A
S
G
D
P
E
E
A
Q
Site 84
T1449
L
V
P
E
H
V
E
T
R
P
L
Y
H
P
H
Site 85
Y1453
H
V
E
T
R
P
L
Y
H
P
H
S
P
G
L
Site 86
S1457
R
P
L
Y
H
P
H
S
P
G
L
L
Q
G
S
Site 87
S1491
I
K
P
R
Q
P
I
S
Y
E
L
R
V
V
I
Site 88
Y1492
K
P
R
Q
P
I
S
Y
E
L
R
V
V
I
W
Site 89
T1513
L
D
D
E
N
P
L
T
G
E
M
S
S
D
I
Site 90
S1517
N
P
L
T
G
E
M
S
S
D
I
Y
V
K
S
Site 91
S1518
P
L
T
G
E
M
S
S
D
I
Y
V
K
S
W
Site 92
Y1521
G
E
M
S
S
D
I
Y
V
K
S
W
V
K
G
Site 93
S1524
S
S
D
I
Y
V
K
S
W
V
K
G
L
E
H
Site 94
S1542
E
T
D
V
H
F
N
S
L
T
G
E
G
N
F
Site 95
T1544
D
V
H
F
N
S
L
T
G
E
G
N
F
N
W
Site 96
Y1559
R
F
V
F
R
F
D
Y
L
P
T
E
R
E
V
Site 97
S1567
L
P
T
E
R
E
V
S
V
W
R
R
S
G
P
Site 98
S1572
E
V
S
V
W
R
R
S
G
P
F
A
L
E
E
Site 99
Y1595
L
V
L
Q
V
W
D
Y
D
R
I
S
A
N
D
Site 100
S1606
S
A
N
D
F
L
G
S
L
E
L
Q
L
P
D
Site 101
S1625
A
R
G
P
E
L
C
S
V
Q
L
A
R
N
G
Site 102
T1710
E
A
E
F
E
L
L
T
V
E
E
A
E
K
R
Site 103
S1733
P
E
P
L
E
K
P
S
R
P
K
T
S
F
N
Site 104
T1737
E
K
P
S
R
P
K
T
S
F
N
W
F
V
N
Site 105
S1738
K
P
S
R
P
K
T
S
F
N
W
F
V
N
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation