KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
Putative rhophilin-2-like protein
Full Name:
Putative rhophilin-2-like protein
Alias:
Type:
Mass (Da):
65945
Number AA:
583
UniProt ID:
A8MT19
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
E
L
E
G
L
N
I
S
V
G
I
Y
Q
N
T
Site 2
Y16
L
N
I
S
V
G
I
Y
Q
N
T
E
E
A
F
Site 3
Y52
K
D
F
I
L
E
H
Y
S
E
D
G
Y
L
Y
Site 4
Y57
E
H
Y
S
E
D
G
Y
L
Y
E
D
E
I
T
Site 5
Y59
Y
S
E
D
G
Y
L
Y
E
D
E
I
T
D
L
Site 6
T64
Y
L
Y
E
D
E
I
T
D
L
M
D
P
R
Q
Site 7
T75
D
P
R
Q
A
C
R
T
P
S
R
D
E
A
R
Site 8
S77
R
Q
A
C
R
T
P
S
R
D
E
A
R
V
E
Site 9
Y103
A
W
I
R
F
K
K
Y
N
T
S
P
R
I
F
Site 10
T105
I
R
F
K
K
Y
N
T
S
P
R
I
F
F
Y
Site 11
Y112
T
S
P
R
I
F
F
Y
R
Y
D
S
L
N
G
Site 12
Y114
P
R
I
F
F
Y
R
Y
D
S
L
N
G
V
L
Site 13
Y142
L
F
N
T
G
A
L
Y
T
Q
I
G
T
W
R
Site 14
T177
V
L
N
Y
L
K
E
T
F
T
H
T
P
S
Y
Site 15
T179
N
Y
L
K
E
T
F
T
H
T
P
S
Y
D
M
Site 16
T181
L
K
E
T
F
T
H
T
P
S
Y
D
M
S
P
Site 17
S183
E
T
F
T
H
T
P
S
Y
D
M
S
P
A
M
Site 18
Y184
T
F
T
H
T
P
S
Y
D
M
S
P
A
M
L
Site 19
S211
E
S
V
F
E
K
I
S
L
P
G
I
R
N
E
Site 20
S244
Q
Q
L
H
A
A
M
S
Q
A
L
V
K
E
N
Site 21
Y301
E
K
C
L
S
Q
L
Y
D
H
M
P
E
G
L
Site 22
T309
D
H
M
P
E
G
L
T
P
L
A
T
L
K
N
Site 23
T313
E
G
L
T
P
L
A
T
L
K
N
D
Q
Q
R
Site 24
S326
Q
R
R
Q
L
G
K
S
H
L
H
R
A
M
A
Site 25
S338
A
M
A
H
H
E
E
S
V
R
E
A
S
L
C
Site 26
S343
E
E
S
V
R
E
A
S
L
C
K
K
L
R
S
Site 27
T368
A
Q
E
R
S
R
L
T
Y
A
Q
H
Q
E
D
Site 28
Y369
Q
E
R
S
R
L
T
Y
A
Q
H
Q
E
D
D
Site 29
S400
Q
E
P
K
G
P
L
S
V
F
L
A
N
K
Q
Site 30
S413
K
Q
W
M
P
P
R
S
N
R
F
T
A
E
E
Site 31
T417
P
P
R
S
N
R
F
T
A
E
E
G
D
L
G
Site 32
T426
E
E
G
D
L
G
F
T
L
R
G
N
A
P
V
Site 33
S477
E
V
M
K
L
L
K
S
F
G
E
D
E
I
E
Site 34
S493
K
V
V
S
L
L
D
S
T
S
S
M
H
N
K
Site 35
S495
V
S
L
L
D
S
T
S
S
M
H
N
K
S
A
Site 36
S496
S
L
L
D
S
T
S
S
M
H
N
K
S
A
T
Site 37
S501
T
S
S
M
H
N
K
S
A
T
Y
S
V
G
M
Site 38
T503
S
M
H
N
K
S
A
T
Y
S
V
G
M
Q
K
Site 39
S505
H
N
K
S
A
T
Y
S
V
G
M
Q
K
T
Y
Site 40
T525
A
I
D
D
D
N
K
T
D
K
T
Q
K
I
S
Site 41
T528
D
D
N
K
T
D
K
T
Q
K
I
S
K
K
L
Site 42
S532
T
D
K
T
Q
K
I
S
K
K
L
S
F
L
S
Site 43
S536
Q
K
I
S
K
K
L
S
F
L
S
W
G
T
N
Site 44
S549
T
N
K
N
R
Q
K
S
A
S
T
L
C
L
P
Site 45
S551
K
N
R
Q
K
S
A
S
T
L
C
L
P
S
V
Site 46
S571
Q
V
K
K
K
L
P
S
P
F
S
L
L
N
S
Site 47
S574
K
K
L
P
S
P
F
S
L
L
N
S
D
S
S
Site 48
S578
S
P
F
S
L
L
N
S
D
S
S
S
Y
_
_
Site 49
S580
F
S
L
L
N
S
D
S
S
S
Y
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation