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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTLL13
Full Name:
Tubulin polyglutamylase TTLL13
Alias:
Tubulin--tyrosine ligase-like protein 13
Type:
Mass (Da):
93645
Number AA:
815
UniProt ID:
A6NNM8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
E
P
S
T
C
R
T
M
E
S
E
E
D
Y
Site 2
Y15
T
M
E
S
E
E
D
Y
V
E
E
K
E
S
E
Site 3
S21
D
Y
V
E
E
K
E
S
E
K
C
V
K
E
G
Site 4
S33
K
E
G
V
T
N
P
S
N
S
S
Q
Q
A
L
Site 5
S35
G
V
T
N
P
S
N
S
S
Q
Q
A
L
L
K
Site 6
Y45
Q
A
L
L
K
A
D
Y
K
A
L
K
N
G
V
Site 7
S87
K
R
R
R
K
R
R
S
L
A
I
N
L
T
N
Site 8
T93
R
S
L
A
I
N
L
T
N
C
K
Y
E
S
V
Site 9
Y97
I
N
L
T
N
C
K
Y
E
S
V
R
R
A
A
Site 10
Y121
E
D
E
E
W
T
L
Y
W
T
D
C
A
V
S
Site 11
Y164
A
R
N
L
N
R
M
Y
K
L
Y
P
S
E
Y
Site 12
Y167
L
N
R
M
Y
K
L
Y
P
S
E
Y
N
I
F
Site 13
Y184
T
W
C
L
P
A
D
Y
G
D
F
Q
S
Y
G
Site 14
S189
A
D
Y
G
D
F
Q
S
Y
G
R
Q
R
K
A
Site 15
Y190
D
Y
G
D
F
Q
S
Y
G
R
Q
R
K
A
R
Site 16
Y199
R
Q
R
K
A
R
T
Y
I
C
K
P
D
S
G
Site 17
T215
Q
G
R
G
I
F
I
T
R
N
P
R
E
I
K
Site 18
T262
C
D
P
L
R
I
F
T
Y
E
E
G
L
A
R
Site 19
Y263
D
P
L
R
I
F
T
Y
E
E
G
L
A
R
F
Site 20
T272
E
G
L
A
R
F
A
T
T
P
Y
M
E
P
S
Site 21
T273
G
L
A
R
F
A
T
T
P
Y
M
E
P
S
H
Site 22
Y275
A
R
F
A
T
T
P
Y
M
E
P
S
H
N
N
Site 23
S310
V
R
D
G
A
V
G
S
K
R
K
L
S
T
L
Site 24
S315
V
G
S
K
R
K
L
S
T
L
N
I
W
L
Q
Site 25
T316
G
S
K
R
K
L
S
T
L
N
I
W
L
Q
E
Site 26
S348
K
T
I
I
S
A
H
S
V
L
R
H
N
Y
R
Site 27
Y354
H
S
V
L
R
H
N
Y
R
T
C
F
P
Q
Y
Site 28
Y361
Y
R
T
C
F
P
Q
Y
L
N
G
G
T
C
A
Site 29
S393
W
L
L
E
V
N
H
S
P
S
F
T
T
D
S
Site 30
S395
L
E
V
N
H
S
P
S
F
T
T
D
S
C
L
Site 31
T397
V
N
H
S
P
S
F
T
T
D
S
C
L
D
Q
Site 32
S400
S
P
S
F
T
T
D
S
C
L
D
Q
E
V
K
Site 33
Y444
K
E
R
L
F
Q
C
Y
R
Q
P
R
E
S
R
Site 34
S450
C
Y
R
Q
P
R
E
S
R
K
E
K
T
E
S
Site 35
T455
R
E
S
R
K
E
K
T
E
S
S
H
V
A
M
Site 36
S457
S
R
K
E
K
T
E
S
S
H
V
A
M
L
D
Site 37
Y468
A
M
L
D
Q
E
R
Y
E
D
S
H
L
G
K
Site 38
Y476
E
D
S
H
L
G
K
Y
R
R
I
Y
P
G
P
Site 39
Y480
L
G
K
Y
R
R
I
Y
P
G
P
D
T
E
K
Site 40
T485
R
I
Y
P
G
P
D
T
E
K
Y
A
R
F
F
Site 41
Y488
P
G
P
D
T
E
K
Y
A
R
F
F
K
H
N
Site 42
S497
R
F
F
K
H
N
G
S
L
F
Q
E
T
A
A
Site 43
S505
L
F
Q
E
T
A
A
S
K
A
R
E
E
C
A
Site 44
T531
E
Q
Q
E
T
S
G
T
K
R
Q
K
A
R
D
Site 45
S549
G
E
S
A
G
E
K
S
R
P
R
A
G
L
Q
Site 46
S557
R
P
R
A
G
L
Q
S
L
S
T
H
L
A
Y
Site 47
S559
R
A
G
L
Q
S
L
S
T
H
L
A
Y
R
N
Site 48
T580
L
L
P
G
Q
L
D
T
M
R
P
Q
E
I
V
Site 49
T615
L
G
I
V
E
Q
L
T
R
L
Q
H
P
G
P
Site 50
S631
G
Q
K
K
L
H
E
S
R
D
R
L
G
S
Q
Site 51
S637
E
S
R
D
R
L
G
S
Q
E
L
K
S
M
S
Site 52
S682
R
I
L
G
A
L
P
S
M
N
A
A
I
P
H
Site 53
Y693
A
I
P
H
V
P
R
Y
H
L
Q
P
K
N
F
Site 54
S711
G
E
P
A
A
I
N
S
C
S
L
S
M
K
K
Site 55
S713
P
A
A
I
N
S
C
S
L
S
M
K
K
A
G
Site 56
S715
A
I
N
S
C
S
L
S
M
K
K
A
G
R
C
Site 57
Y723
M
K
K
A
G
R
C
Y
F
S
S
A
R
I
R
Site 58
S725
K
A
G
R
C
Y
F
S
S
A
R
I
R
L
T
Site 59
S726
A
G
R
C
Y
F
S
S
A
R
I
R
L
T
S
Site 60
T732
S
S
A
R
I
R
L
T
S
Q
G
Q
A
S
R
Site 61
S733
S
A
R
I
R
L
T
S
Q
G
Q
A
S
R
R
Site 62
S738
L
T
S
Q
G
Q
A
S
R
R
L
E
A
I
N
Site 63
T755
L
A
G
S
V
P
P
T
L
T
P
K
Q
G
Y
Site 64
T757
G
S
V
P
P
T
L
T
P
K
Q
G
Y
F
L
Site 65
S771
L
Q
P
E
R
V
A
S
D
S
W
T
E
C
T
Site 66
S773
P
E
R
V
A
S
D
S
W
T
E
C
T
L
P
Site 67
T775
R
V
A
S
D
S
W
T
E
C
T
L
P
S
M
Site 68
T778
S
D
S
W
T
E
C
T
L
P
S
M
V
N
S
Site 69
S785
T
L
P
S
M
V
N
S
E
H
R
A
A
K
V
Site 70
S798
K
V
P
L
C
P
A
S
A
P
M
L
Q
R
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation