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Updated November 2019
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Protein Info
Short Name:
RIMBP3B
Full Name:
RIMS-binding protein 3B
Alias:
RIMS-binding protein 3.2
Type:
Mass (Da):
169918
Number AA:
1545
UniProt ID:
A6NNM3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S56
L
V
N
R
G
H
C
S
R
P
G
A
S
E
V
Site 2
T83
L
A
Q
L
R
W
Q
T
D
G
E
Q
A
A
R
Site 3
Y93
E
Q
A
A
R
I
R
Y
L
Q
A
A
L
E
V
Site 4
Y108
E
R
Q
L
F
L
K
Y
I
L
A
H
F
R
G
Site 5
S120
F
R
G
H
P
A
L
S
G
S
P
D
P
Q
A
Site 6
S122
G
H
P
A
L
S
G
S
P
D
P
Q
A
V
H
Site 7
S130
P
D
P
Q
A
V
H
S
L
E
E
P
L
P
Q
Site 8
T138
L
E
E
P
L
P
Q
T
S
S
G
S
C
H
A
Site 9
S140
E
P
L
P
Q
T
S
S
G
S
C
H
A
P
K
Site 10
S154
K
P
A
C
Q
L
G
S
L
D
S
L
S
A
E
Site 11
S173
S
R
S
L
G
L
V
S
S
A
C
S
S
S
P
Site 12
S174
R
S
L
G
L
V
S
S
A
C
S
S
S
P
D
Site 13
S179
V
S
S
A
C
S
S
S
P
D
G
L
L
S
T
Site 14
S185
S
S
P
D
G
L
L
S
T
H
A
S
S
L
D
Site 15
T186
S
P
D
G
L
L
S
T
H
A
S
S
L
D
C
Site 16
S201
F
A
P
A
C
S
R
S
L
D
S
T
R
S
L
Site 17
S204
A
C
S
R
S
L
D
S
T
R
S
L
P
K
A
Site 18
T205
C
S
R
S
L
D
S
T
R
S
L
P
K
A
S
Site 19
S207
R
S
L
D
S
T
R
S
L
P
K
A
S
K
S
Site 20
S214
S
L
P
K
A
S
K
S
E
E
R
P
S
S
P
Site 21
S219
S
K
S
E
E
R
P
S
S
P
D
T
S
T
P
Site 22
S220
K
S
E
E
R
P
S
S
P
D
T
S
T
P
G
Site 23
T223
E
R
P
S
S
P
D
T
S
T
P
G
S
R
R
Site 24
S224
R
P
S
S
P
D
T
S
T
P
G
S
R
R
L
Site 25
T225
P
S
S
P
D
T
S
T
P
G
S
R
R
L
S
Site 26
S228
P
D
T
S
T
P
G
S
R
R
L
S
P
P
P
Site 27
S232
T
P
G
S
R
R
L
S
P
P
P
S
P
L
P
Site 28
S236
R
R
L
S
P
P
P
S
P
L
P
P
P
P
P
Site 29
S245
L
P
P
P
P
P
P
S
A
H
R
K
L
S
N
Site 30
S251
P
S
A
H
R
K
L
S
N
P
R
G
G
E
G
Site 31
S259
N
P
R
G
G
E
G
S
E
S
Q
P
C
E
V
Site 32
S261
R
G
G
E
G
S
E
S
Q
P
C
E
V
L
T
Site 33
T268
S
Q
P
C
E
V
L
T
P
S
P
P
G
L
G
Site 34
S270
P
C
E
V
L
T
P
S
P
P
G
L
G
H
H
Site 35
Y298
W
V
L
A
R
R
C
Y
T
L
Q
E
E
N
K
Site 36
T299
V
L
A
R
R
C
Y
T
L
Q
E
E
N
K
Q
Site 37
Y314
L
R
R
A
G
C
P
Y
Q
A
D
E
K
V
K
Site 38
T347
R
A
R
E
L
Q
E
T
N
L
R
A
V
S
A
Site 39
S353
E
T
N
L
R
A
V
S
A
P
I
P
G
E
S
Site 40
S379
R
Q
R
A
R
D
L
S
E
Q
A
S
A
P
L
Site 41
S383
R
D
L
S
E
Q
A
S
A
P
L
A
K
D
K
Site 42
S412
R
V
A
S
G
P
C
S
D
L
H
T
G
R
G
Site 43
T416
G
P
C
S
D
L
H
T
G
R
G
G
P
C
T
Site 44
T423
T
G
R
G
G
P
C
T
Q
W
L
N
V
R
D
Site 45
S438
L
D
R
L
Q
R
E
S
Q
R
E
V
L
R
L
Site 46
T509
R
R
G
E
E
A
E
T
Q
L
Q
A
A
L
L
Site 47
T532
N
G
R
L
Q
A
K
T
D
W
V
R
K
V
E
Site 48
S543
R
K
V
E
A
E
N
S
E
V
R
G
H
L
G
Site 49
S559
A
C
Q
E
R
D
A
S
G
L
I
A
E
Q
L
Site 50
S616
P
E
Q
P
W
E
T
S
Q
M
P
E
S
Q
V
Site 51
S621
E
T
S
Q
M
P
E
S
Q
V
K
G
S
R
R
Site 52
S626
P
E
S
Q
V
K
G
S
R
R
P
K
F
H
A
Site 53
Y638
F
H
A
R
P
E
D
Y
A
V
S
Q
P
N
R
Site 54
S641
R
P
E
D
Y
A
V
S
Q
P
N
R
D
I
Q
Site 55
S654
I
Q
E
K
R
E
A
S
L
E
E
S
P
V
A
Site 56
S658
R
E
A
S
L
E
E
S
P
V
A
L
G
E
S
Site 57
S672
S
A
S
V
P
Q
V
S
E
T
V
P
A
S
Q
Site 58
T674
S
V
P
Q
V
S
E
T
V
P
A
S
Q
P
L
Site 59
S678
V
S
E
T
V
P
A
S
Q
P
L
S
K
K
T
Site 60
S682
V
P
A
S
Q
P
L
S
K
K
T
S
S
Q
S
Site 61
T685
S
Q
P
L
S
K
K
T
S
S
Q
S
N
S
S
Site 62
S686
Q
P
L
S
K
K
T
S
S
Q
S
N
S
S
S
Site 63
S687
P
L
S
K
K
T
S
S
Q
S
N
S
S
S
E
Site 64
S689
S
K
K
T
S
S
Q
S
N
S
S
S
E
G
S
Site 65
S691
K
T
S
S
Q
S
N
S
S
S
E
G
S
M
W
Site 66
S692
T
S
S
Q
S
N
S
S
S
E
G
S
M
W
A
Site 67
S693
S
S
Q
S
N
S
S
S
E
G
S
M
W
A
T
Site 68
S696
S
N
S
S
S
E
G
S
M
W
A
T
V
P
S
Site 69
T700
S
E
G
S
M
W
A
T
V
P
S
S
P
T
L
Site 70
S704
M
W
A
T
V
P
S
S
P
T
L
D
R
D
T
Site 71
T711
S
P
T
L
D
R
D
T
A
S
E
V
D
D
L
Site 72
S713
T
L
D
R
D
T
A
S
E
V
D
D
L
E
P
Site 73
S724
D
L
E
P
D
S
V
S
L
A
L
E
M
G
G
Site 74
S732
L
A
L
E
M
G
G
S
A
A
P
A
A
P
K
Site 75
Y749
I
F
M
A
Q
Y
N
Y
N
P
F
E
G
P
N
Site 76
Y783
D
M
D
E
D
G
F
Y
E
G
E
L
D
D
G
Site 77
S797
G
R
R
G
L
V
P
S
N
F
V
E
Q
I
P
Site 78
S816
P
G
C
L
P
A
K
S
P
D
L
G
P
S
Q
Site 79
S822
K
S
P
D
L
G
P
S
Q
L
P
A
G
Q
D
Site 80
S836
D
E
A
L
E
E
D
S
L
L
S
G
K
A
Q
Site 81
S858
C
Q
M
V
R
V
G
S
K
T
E
V
A
T
E
Site 82
T871
T
E
I
L
D
T
K
T
E
A
C
Q
L
G
L
Site 83
T918
T
A
T
S
A
N
I
T
W
V
Y
S
S
H
R
Site 84
Y921
S
A
N
I
T
W
V
Y
S
S
H
R
H
P
H
Site 85
Y931
H
R
H
P
H
V
V
Y
L
D
D
R
E
H
A
Site 86
T940
D
D
R
E
H
A
L
T
P
A
G
V
S
C
Y
Site 87
Y958
G
L
C
P
G
T
H
Y
R
V
R
V
E
V
R
Site 88
Y974
P
W
D
L
L
Q
V
Y
W
G
T
M
S
S
T
Site 89
S1024
T
I
D
S
A
G
S
S
N
G
V
Q
V
T
G
Site 90
T1064
S
Q
L
Q
V
P
L
T
W
Q
K
V
S
V
R
Site 91
S1074
K
V
S
V
R
T
M
S
L
C
G
E
S
L
D
Site 92
S1079
T
M
S
L
C
G
E
S
L
D
S
V
P
A
Q
Site 93
S1082
L
C
G
E
S
L
D
S
V
P
A
Q
I
P
E
Site 94
T1100
M
C
H
R
W
P
E
T
P
P
F
S
Y
T
C
Site 95
S1104
W
P
E
T
P
P
F
S
Y
T
C
G
D
P
S
Site 96
Y1105
P
E
T
P
P
F
S
Y
T
C
G
D
P
S
T
Site 97
T1106
E
T
P
P
F
S
Y
T
C
G
D
P
S
T
Y
Site 98
S1111
S
Y
T
C
G
D
P
S
T
Y
R
V
T
F
P
Site 99
T1112
Y
T
C
G
D
P
S
T
Y
R
V
T
F
P
V
Site 100
Y1113
T
C
G
D
P
S
T
Y
R
V
T
F
P
V
C
Site 101
T1116
D
P
S
T
Y
R
V
T
F
P
V
C
P
Q
K
Site 102
S1125
P
V
C
P
Q
K
L
S
L
A
P
P
S
A
K
Site 103
S1130
K
L
S
L
A
P
P
S
A
K
A
S
P
H
N
Site 104
S1134
A
P
P
S
A
K
A
S
P
H
N
P
G
S
C
Site 105
S1140
A
S
P
H
N
P
G
S
C
G
E
P
Q
A
K
Site 106
S1161
E
E
P
P
R
R
Q
S
P
V
S
N
L
G
S
Site 107
S1164
P
R
R
Q
S
P
V
S
N
L
G
S
E
G
E
Site 108
S1168
S
P
V
S
N
L
G
S
E
G
E
C
P
S
S
Site 109
S1174
G
S
E
G
E
C
P
S
S
G
A
G
S
Q
A
Site 110
S1175
S
E
G
E
C
P
S
S
G
A
G
S
Q
A
Q
Site 111
S1179
C
P
S
S
G
A
G
S
Q
A
Q
E
L
A
E
Site 112
S1200
K
D
L
L
F
Q
K
S
P
Q
N
H
R
P
P
Site 113
S1208
P
Q
N
H
R
P
P
S
V
S
D
Q
P
G
E
Site 114
S1210
N
H
R
P
P
S
V
S
D
Q
P
G
E
K
E
Site 115
Y1220
P
G
E
K
E
N
C
Y
Q
H
M
G
T
S
K
Site 116
S1228
Q
H
M
G
T
S
K
S
P
A
P
G
F
I
H
Site 117
T1238
P
G
F
I
H
L
R
T
E
C
G
P
R
K
E
Site 118
T1267
K
Q
D
A
Q
G
F
T
P
P
Q
L
G
A
S
Site 119
S1274
T
P
P
Q
L
G
A
S
Q
Q
Y
A
S
D
F
Site 120
S1279
G
A
S
Q
Q
Y
A
S
D
F
H
N
V
L
K
Site 121
T1299
L
C
L
D
L
R
G
T
E
R
R
E
E
R
R
Site 122
S1312
R
R
E
P
E
P
H
S
R
Q
G
Q
A
L
G
Site 123
S1330
G
C
Q
L
H
E
P
S
S
A
L
C
P
A
P
Site 124
S1331
C
Q
L
H
E
P
S
S
A
L
C
P
A
P
S
Site 125
T1354
G
G
P
Q
Q
L
G
T
G
A
N
T
P
A
R
Site 126
T1401
R
V
W
G
S
Q
D
T
H
D
F
Y
L
S
E
Site 127
Y1405
S
Q
D
T
H
D
F
Y
L
S
E
C
N
R
Q
Site 128
T1431
M
E
V
G
T
E
Q
T
D
R
R
W
R
S
P
Site 129
S1437
Q
T
D
R
R
W
R
S
P
A
Q
G
H
L
P
Site 130
S1445
P
A
Q
G
H
L
P
S
V
A
H
L
E
D
F
Site 131
T1456
L
E
D
F
Q
G
L
T
I
P
Q
G
S
S
L
Site 132
S1469
S
L
V
L
Q
G
N
S
K
R
L
P
L
W
T
Site 133
Y1512
A
G
D
V
V
M
V
Y
G
P
M
D
D
Q
G
Site 134
Y1521
P
M
D
D
Q
G
F
Y
Y
G
E
L
G
G
H
Site 135
Y1522
M
D
D
Q
G
F
Y
Y
G
E
L
G
G
H
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation