PhosphoNET

           
Protein Info 
   
Short Name:  MARCH-XI
Full Name:  E3 ubiquitin-protein ligase MARCH11
Alias:  EC 6.3.2.-; MARCH-XI; Membrane-associated ring finger 11, C3HC4
Type:  Uncharacterized protein
Mass (Da):  43878
Number AA:  402
UniProt ID:  A6NNE9
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0031410  GO:0016021   Uniprot OncoNet
Molecular Function:  GO:0016874  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0019941     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S10FEGGHGGSRCRGAES
Site 2T33PPPPPPPTPPPGEPA
Site 3Y48PVPAAPRYLPPLPAS
Site 4S55YLPPLPASPETPERA
Site 5T58PLPASPETPERAAGP
Site 6S66PERAAGPSEPLGEVA
Site 7S102EVAAAGDSGEGPRRL
Site 8S122AKGGPGESEAGAGGE
Site 9T141GAGDQPETRSVCSSR
Site 10S143GDQPETRSVCSSRSS
Site 11S146PETRSVCSSRSSSSG
Site 12S147ETRSVCSSRSSSSGG
Site 13S149RSVCSSRSSSSGGGD
Site 14S150SVCSSRSSSSGGGDQ
Site 15S151VCSSRSSSSGGGDQR
Site 16T195CDGSVRYTHQLCLLK
Site 17T238QWQSISITLVEKVQM
Site 18T328VLNYDKATDIEESSR
Site 19S333KATDIEESSRGESST
Site 20S334ATDIEESSRGESSTS
Site 21S338EESSRGESSTSRTLW
Site 22S339ESSRGESSTSRTLWL
Site 23T340SSRGESSTSRTLWLP
Site 24S341SRGESSTSRTLWLPL
Site 25T343GESSTSRTLWLPLTA
Site 26T349RTLWLPLTALRNRNL
Site 27T360NRNLVHPTQLTSPRF
Site 28T363LVHPTQLTSPRFQCG
Site 29S364VHPTQLTSPRFQCGY
Site 30S387MRPHEDLSEDNSSGE
Site 31S391EDLSEDNSSGEVVMR
Site 32S392DLSEDNSSGEVVMRV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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