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Updated November 2019
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Protein Info
Short Name:
FIGNL2
Full Name:
Putative fidgetin-like protein 2
Alias:
Type:
Mass (Da):
66603
Number AA:
653
UniProt ID:
A6NMB9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
P
E
Q
H
L
D
V
S
S
T
T
P
S
P
A
Site 2
S23
E
Q
H
L
D
V
S
S
T
T
P
S
P
A
H
Site 3
T24
Q
H
L
D
V
S
S
T
T
P
S
P
A
H
K
Site 4
T25
H
L
D
V
S
S
T
T
P
S
P
A
H
K
L
Site 5
S27
D
V
S
S
T
T
P
S
P
A
H
K
L
E
L
Site 6
Y63
A
S
N
L
L
K
R
Y
A
E
K
Y
S
G
V
Site 7
Y67
L
K
R
Y
A
E
K
Y
S
G
V
L
D
S
P
Site 8
S73
K
Y
S
G
V
L
D
S
P
Y
E
R
P
A
L
Site 9
Y75
S
G
V
L
D
S
P
Y
E
R
P
A
L
G
G
Site 10
Y83
E
R
P
A
L
G
G
Y
S
D
A
S
F
L
N
Site 11
S84
R
P
A
L
G
G
Y
S
D
A
S
F
L
N
G
Site 12
S87
L
G
G
Y
S
D
A
S
F
L
N
G
A
K
G
Site 13
Y106
W
P
G
P
E
P
P
Y
P
L
A
S
L
H
E
Site 14
S110
E
P
P
Y
P
L
A
S
L
H
E
G
L
P
G
Site 15
T118
L
H
E
G
L
P
G
T
K
S
G
G
G
G
G
Site 16
S120
E
G
L
P
G
T
K
S
G
G
G
G
G
S
G
Site 17
S126
K
S
G
G
G
G
G
S
G
A
L
G
G
S
P
Site 18
Y144
G
N
L
P
E
P
L
Y
A
G
N
A
C
G
G
Site 19
Y158
G
P
S
A
A
P
E
Y
A
A
G
Y
G
G
G
Site 20
Y162
A
P
E
Y
A
A
G
Y
G
G
G
Y
L
A
P
Site 21
Y196
Q
P
P
P
P
P
G
Y
G
P
S
A
P
L
Y
Site 22
S199
P
P
P
G
Y
G
P
S
A
P
L
Y
N
Y
P
Site 23
Y203
Y
G
P
S
A
P
L
Y
N
Y
P
A
G
G
Y
Site 24
Y205
P
S
A
P
L
Y
N
Y
P
A
G
G
Y
A
A
Site 25
Y216
G
Y
A
A
Q
P
G
Y
G
A
L
P
P
P
P
Site 26
Y230
P
G
P
P
P
A
P
Y
L
T
P
G
L
P
A
Site 27
T232
P
P
P
A
P
Y
L
T
P
G
L
P
A
P
T
Site 28
T239
T
P
G
L
P
A
P
T
P
L
P
A
P
A
P
Site 29
T254
P
T
A
Y
G
F
P
T
A
A
P
G
A
E
S
Site 30
S264
P
G
A
E
S
G
L
S
L
K
R
K
A
A
D
Site 31
Y281
P
E
G
R
Y
R
K
Y
A
Y
E
P
A
K
A
Site 32
S295
A
P
V
A
D
G
A
S
Y
P
A
A
D
N
G
Site 33
Y296
P
V
A
D
G
A
S
Y
P
A
A
D
N
G
E
Site 34
S321
P
G
A
A
E
E
A
S
G
K
Y
G
G
G
V
Site 35
Y338
K
V
L
G
S
P
V
Y
G
P
Q
L
E
P
F
Site 36
S363
R
G
G
F
A
V
P
S
G
E
T
P
K
G
V
Site 37
T366
F
A
V
P
S
G
E
T
P
K
G
V
D
P
G
Site 38
T379
P
G
A
L
E
L
V
T
S
K
M
V
D
C
G
Site 39
S380
G
A
L
E
L
V
T
S
K
M
V
D
C
G
P
Site 40
Y418
P
L
L
R
P
P
A
Y
P
G
S
L
R
P
P
Site 41
S421
R
P
P
A
Y
P
G
S
L
R
P
P
R
T
V
Site 42
T427
G
S
L
R
P
P
R
T
V
L
L
F
G
P
R
Site 43
T545
P
A
A
L
D
E
A
T
R
R
R
F
S
L
R
Site 44
S550
E
A
T
R
R
R
F
S
L
R
F
Y
V
A
L
Site 45
Y554
R
R
F
S
L
R
F
Y
V
A
L
P
D
S
P
Site 46
S619
P
G
L
Q
R
P
L
S
Y
K
D
L
E
A
A
Site 47
S635
A
K
V
G
P
R
A
S
A
K
E
L
D
S
F
Site 48
S641
A
S
A
K
E
L
D
S
F
V
E
W
D
K
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation