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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGAP5
Full Name:
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5
Alias:
Centaurin-gamma-like family member 2
Type:
Mass (Da):
72983
Number AA:
663
UniProt ID:
A6NIR3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
E
F
D
Q
Q
Q
G
S
V
C
P
S
E
S
E
Site 2
S27
Q
Q
G
S
V
C
P
S
E
S
E
I
Y
E
A
Site 3
S29
G
S
V
C
P
S
E
S
E
I
Y
E
A
G
A
Site 4
Y32
C
P
S
E
S
E
I
Y
E
A
G
A
G
D
R
Site 5
S81
E
A
L
E
F
N
P
S
A
N
P
E
A
S
T
Site 6
S94
S
T
I
F
Q
R
N
S
Q
T
D
V
V
E
I
Site 7
S104
D
V
V
E
I
R
R
S
N
C
T
N
H
V
S
Site 8
T107
E
I
R
R
S
N
C
T
N
H
V
S
T
E
R
Site 9
S111
S
N
C
T
N
H
V
S
T
E
R
F
S
Q
Q
Site 10
T112
N
C
T
N
H
V
S
T
E
R
F
S
Q
Q
Y
Site 11
S116
H
V
S
T
E
R
F
S
Q
Q
Y
S
S
C
S
Site 12
Y119
T
E
R
F
S
Q
Q
Y
S
S
C
S
T
I
F
Site 13
S120
E
R
F
S
Q
Q
Y
S
S
C
S
T
I
F
L
Site 14
S121
R
F
S
Q
Q
Y
S
S
C
S
T
I
F
L
D
Site 15
S123
S
Q
Q
Y
S
S
C
S
T
I
F
L
D
D
S
Site 16
S130
S
T
I
F
L
D
D
S
T
A
S
Q
H
Y
L
Site 17
T131
T
I
F
L
D
D
S
T
A
S
Q
H
Y
L
T
Site 18
S133
F
L
D
D
S
T
A
S
Q
H
Y
L
T
M
T
Site 19
T153
L
E
I
P
H
H
I
T
Q
R
D
A
D
R
S
Site 20
S160
T
Q
R
D
A
D
R
S
L
S
I
P
D
E
Q
Site 21
S162
R
D
A
D
R
S
L
S
I
P
D
E
Q
L
H
Site 22
S170
I
P
D
E
Q
L
H
S
F
A
V
S
T
V
H
Site 23
S174
Q
L
H
S
F
A
V
S
T
V
H
I
T
K
N
Site 24
T175
L
H
S
F
A
V
S
T
V
H
I
T
K
N
R
Site 25
S187
K
N
R
N
G
G
G
S
L
N
N
Y
S
S
S
Site 26
Y191
G
G
G
S
L
N
N
Y
S
S
S
I
P
S
T
Site 27
S192
G
G
S
L
N
N
Y
S
S
S
I
P
S
T
P
Site 28
S193
G
S
L
N
N
Y
S
S
S
I
P
S
T
P
S
Site 29
S194
S
L
N
N
Y
S
S
S
I
P
S
T
P
S
T
Site 30
S197
N
Y
S
S
S
I
P
S
T
P
S
T
S
Q
E
Site 31
T198
Y
S
S
S
I
P
S
T
P
S
T
S
Q
E
D
Site 32
S200
S
S
I
P
S
T
P
S
T
S
Q
E
D
P
Q
Site 33
T201
S
I
P
S
T
P
S
T
S
Q
E
D
P
Q
F
Site 34
S202
I
P
S
T
P
S
T
S
Q
E
D
P
Q
F
S
Site 35
S209
S
Q
E
D
P
Q
F
S
V
P
P
T
A
N
T
Site 36
T213
P
Q
F
S
V
P
P
T
A
N
T
P
T
P
V
Site 37
T216
S
V
P
P
T
A
N
T
P
T
P
V
C
K
R
Site 38
T218
P
P
T
A
N
T
P
T
P
V
C
K
R
S
M
Site 39
S228
C
K
R
S
M
R
W
S
N
L
F
T
S
E
K
Site 40
T232
M
R
W
S
N
L
F
T
S
E
K
G
S
H
P
Site 41
S233
R
W
S
N
L
F
T
S
E
K
G
S
H
P
D
Site 42
S237
L
F
T
S
E
K
G
S
H
P
D
K
E
R
K
Site 43
T252
A
P
E
N
H
A
D
T
I
G
S
G
R
A
I
Site 44
S255
N
H
A
D
T
I
G
S
G
R
A
I
P
I
K
Site 45
T276
R
S
G
K
W
L
K
T
W
K
K
K
Y
V
T
Site 46
Y281
L
K
T
W
K
K
K
Y
V
T
L
C
S
N
G
Site 47
T283
T
W
K
K
K
Y
V
T
L
C
S
N
G
V
L
Site 48
Y292
C
S
N
G
V
L
T
Y
Y
S
S
L
G
D
Y
Site 49
Y293
S
N
G
V
L
T
Y
Y
S
S
L
G
D
Y
M
Site 50
S295
G
V
L
T
Y
Y
S
S
L
G
D
Y
M
K
N
Site 51
Y299
Y
Y
S
S
L
G
D
Y
M
K
N
I
H
K
K
Site 52
S313
K
E
I
D
L
R
T
S
T
I
K
V
P
G
K
Site 53
T314
E
I
D
L
R
T
S
T
I
K
V
P
G
K
W
Site 54
S323
K
V
P
G
K
W
P
S
L
A
T
S
A
C
A
Site 55
S333
T
S
A
C
A
P
I
S
S
S
K
S
N
G
L
Site 56
S334
S
A
C
A
P
I
S
S
S
K
S
N
G
L
S
Site 57
S335
A
C
A
P
I
S
S
S
K
S
N
G
L
S
K
Site 58
S337
A
P
I
S
S
S
K
S
N
G
L
S
K
D
M
Site 59
S341
S
S
K
S
N
G
L
S
K
D
M
D
T
G
L
Site 60
T346
G
L
S
K
D
M
D
T
G
L
G
D
S
I
C
Site 61
S357
D
S
I
C
F
S
P
S
I
S
S
T
T
S
P
Site 62
T361
F
S
P
S
I
S
S
T
T
S
P
K
L
N
P
Site 63
S363
P
S
I
S
S
T
T
S
P
K
L
N
P
P
P
Site 64
S371
P
K
L
N
P
P
P
S
P
H
A
N
K
K
K
Site 65
Y405
W
H
F
E
A
T
T
Y
E
E
R
D
A
W
V
Site 66
S422
I
Q
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Site 67
S425
Q
I
L
A
S
L
Q
S
C
E
S
S
K
S
K
Site 68
S428
A
S
L
Q
S
C
E
S
S
K
S
K
S
Q
L
Site 69
S429
S
L
Q
S
C
E
S
S
K
S
K
S
Q
L
T
Site 70
S431
Q
S
C
E
S
S
K
S
K
S
Q
L
T
S
Q
Site 71
S433
C
E
S
S
K
S
K
S
Q
L
T
S
Q
S
E
Site 72
S437
K
S
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Site 73
S439
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Q
S
Site 74
Y459
G
N
A
H
C
V
D
Y
E
T
Q
N
P
K
W
Site 75
S485
E
C
S
G
I
H
R
S
L
G
T
R
L
S
R
Site 76
S491
R
S
L
G
T
R
L
S
R
V
R
S
L
E
L
Site 77
S495
T
R
L
S
R
V
R
S
L
E
L
D
D
W
P
Site 78
S511
E
L
R
K
V
M
S
S
I
G
N
D
L
A
N
Site 79
S519
I
G
N
D
L
A
N
S
I
W
E
G
S
S
Q
Site 80
T529
E
G
S
S
Q
G
Q
T
K
P
S
V
K
S
T
Site 81
S532
S
Q
G
Q
T
K
P
S
V
K
S
T
R
E
E
Site 82
S535
Q
T
K
P
S
V
K
S
T
R
E
E
K
E
R
Site 83
T536
T
K
P
S
V
K
S
T
R
E
E
K
E
R
W
Site 84
S546
E
K
E
R
W
I
R
S
K
Y
E
E
K
L
F
Site 85
Y548
E
R
W
I
R
S
K
Y
E
E
K
L
F
L
A
Site 86
T572
G
Q
H
L
L
R
A
T
A
D
E
D
L
Q
T
Site 87
T595
S
R
E
E
V
N
E
T
C
G
E
G
D
G
C
Site 88
T639
A
H
G
N
T
A
L
T
Y
A
R
Q
A
S
S
Site 89
Y640
H
G
N
T
A
L
T
Y
A
R
Q
A
S
S
Q
Site 90
S645
L
T
Y
A
R
Q
A
S
S
Q
E
C
I
N
V
Site 91
S646
T
Y
A
R
Q
A
S
S
Q
E
C
I
N
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation