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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC154
Full Name:
Coiled-coil domain-containing protein 154
Alias:
Type:
Mass (Da):
76013
Number AA:
674
UniProt ID:
A6NI56
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
E
L
A
D
S
G
P
S
G
A
S
A
Site 2
S13
D
S
G
P
S
G
A
S
A
P
S
Q
L
R
A
Site 3
S16
P
S
G
A
S
A
P
S
Q
L
R
A
V
T
L
Site 4
S41
L
A
S
P
E
P
L
S
L
E
E
L
S
E
R
Site 5
S46
P
L
S
L
E
E
L
S
E
R
Y
E
S
S
H
Site 6
Y49
L
E
E
L
S
E
R
Y
E
S
S
H
P
T
S
Site 7
S51
E
L
S
E
R
Y
E
S
S
H
P
T
S
T
A
Site 8
S52
L
S
E
R
Y
E
S
S
H
P
T
S
T
A
S
Site 9
T55
R
Y
E
S
S
H
P
T
S
T
A
S
V
P
E
Site 10
S56
Y
E
S
S
H
P
T
S
T
A
S
V
P
E
Q
Site 11
S59
S
H
P
T
S
T
A
S
V
P
E
Q
D
T
A
Site 12
T97
K
Q
R
C
E
R
A
T
R
S
L
L
R
E
L
Site 13
S99
R
C
E
R
A
T
R
S
L
L
R
E
L
L
Q
Site 14
S116
A
R
V
Q
L
Q
G
S
E
L
R
Q
L
Q
Q
Site 15
T189
G
L
R
L
A
K
L
T
D
L
L
Q
Q
E
E
Site 16
S213
L
Q
K
N
Q
E
D
S
S
R
R
V
D
L
E
Site 17
S214
Q
K
N
Q
E
D
S
S
R
R
V
D
L
E
V
Site 18
S236
T
K
L
G
E
E
V
S
L
R
F
L
K
R
E
Site 19
S264
L
E
K
R
M
K
A
S
E
S
S
R
L
K
L
Site 20
S266
K
R
M
K
A
S
E
S
S
R
L
K
L
E
G
Site 21
S274
S
R
L
K
L
E
G
S
L
R
G
E
L
E
S
Site 22
S281
S
L
R
G
E
L
E
S
R
W
E
K
L
R
G
Site 23
S313
G
G
R
R
A
E
E
S
H
L
L
E
Q
C
Q
Site 24
S360
A
K
G
R
L
E
E
S
R
A
G
E
L
A
A
Site 25
Y368
R
A
G
E
L
A
A
Y
V
Q
E
N
L
E
A
Site 26
S404
K
S
R
A
L
E
A
S
V
A
Q
L
A
G
Q
Site 27
S416
A
G
Q
L
K
E
L
S
G
H
L
P
A
L
S
Site 28
S423
S
G
H
L
P
A
L
S
S
R
L
D
L
Q
E
Site 29
S424
G
H
L
P
A
L
S
S
R
L
D
L
Q
E
Q
Site 30
S438
Q
M
L
G
L
R
L
S
E
A
K
T
E
W
E
Site 31
T442
L
R
L
S
E
A
K
T
E
W
E
G
A
E
R
Site 32
S451
W
E
G
A
E
R
K
S
L
E
D
L
A
R
W
Site 33
S482
G
L
P
Q
Q
I
E
S
V
S
D
K
C
L
L
Site 34
S484
P
Q
Q
I
E
S
V
S
D
K
C
L
L
H
K
Site 35
S492
D
K
C
L
L
H
K
S
D
S
D
L
R
I
S
Site 36
S494
C
L
L
H
K
S
D
S
D
L
R
I
S
A
E
Site 37
S499
S
D
S
D
L
R
I
S
A
E
G
K
A
R
E
Site 38
T567
I
Q
N
L
R
F
N
T
E
A
R
L
R
T
Q
Site 39
T573
N
T
E
A
R
L
R
T
Q
E
M
A
T
L
W
Site 40
T578
L
R
T
Q
E
M
A
T
L
W
E
S
V
L
R
Site 41
S582
E
M
A
T
L
W
E
S
V
L
R
L
W
S
E
Site 42
S588
E
S
V
L
R
L
W
S
E
E
G
P
R
T
P
Site 43
T594
W
S
E
E
G
P
R
T
P
L
G
S
W
K
A
Site 44
S598
G
P
R
T
P
L
G
S
W
K
A
L
P
S
L
Site 45
S604
G
S
W
K
A
L
P
S
L
V
R
P
R
V
F
Site 46
S640
R
W
L
R
W
K
A
S
L
I
K
L
R
A
L
Site 47
S659
G
V
L
E
K
P
H
S
Q
E
Q
V
Q
Q
L
Site 48
T667
Q
E
Q
V
Q
Q
L
T
P
S
L
F
I
Q
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation