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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBC1 domain family member 3C-like protein ENSP00000341742
Full Name:
TBC1 domain family member 3C-like protein ENSP00000341742
Alias:
Type:
Mass (Da):
62251
Number AA:
549
UniProt ID:
A6NI40
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
D
V
V
E
V
A
G
S
W
W
A
Q
E
R
E
Site 2
Y22
R
E
D
I
I
M
K
Y
E
K
G
H
R
A
G
Site 3
Y42
G
P
K
P
F
R
S
Y
N
N
N
V
D
H
L
Site 4
T61
E
T
E
L
P
P
L
T
A
R
E
A
K
Q
I
Site 5
S73
K
Q
I
R
R
E
I
S
R
K
S
K
W
V
D
Site 6
S76
R
R
E
I
S
R
K
S
K
W
V
D
M
L
G
Site 7
Y88
M
L
G
D
W
E
K
Y
K
S
S
R
K
L
I
Site 8
S90
G
D
W
E
K
Y
K
S
S
R
K
L
I
D
R
Site 9
Y99
R
K
L
I
D
R
A
Y
K
G
M
P
M
N
I
Site 10
S112
N
I
R
G
P
M
W
S
V
L
L
N
I
E
E
Site 11
S139
K
E
K
G
K
R
S
S
E
H
I
Q
R
I
D
Site 12
S150
Q
R
I
D
R
D
I
S
G
T
L
R
K
H
M
Site 13
T152
I
D
R
D
I
S
G
T
L
R
K
H
M
F
F
Site 14
Y163
H
M
F
F
R
D
R
Y
G
T
K
Q
R
E
L
Site 15
T165
F
F
R
D
R
Y
G
T
K
Q
R
E
L
L
H
Site 16
Y186
E
Y
N
P
E
V
G
Y
C
R
D
L
S
H
I
Site 17
S220
L
L
A
S
E
R
H
S
L
Q
G
F
H
S
P
Site 18
S226
H
S
L
Q
G
F
H
S
P
N
G
G
T
V
Q
Site 19
S246
Q
E
H
V
V
A
T
S
Q
S
K
T
M
G
H
Site 20
T250
V
A
T
S
Q
S
K
T
M
G
H
Q
D
K
K
Site 21
S278
R
I
L
I
D
G
I
S
L
G
L
T
L
R
L
Site 22
T282
D
G
I
S
L
G
L
T
L
R
L
W
D
V
Y
Site 23
Y289
T
L
R
L
W
D
V
Y
L
V
E
G
E
Q
A
Site 24
T313
K
V
Q
Q
K
R
L
T
K
T
S
R
C
G
P
Site 25
T315
Q
Q
K
R
L
T
K
T
S
R
C
G
P
W
A
Site 26
S316
Q
K
R
L
T
K
T
S
R
C
G
P
W
A
R
Site 27
T338
T
W
A
R
D
E
D
T
V
L
K
H
L
R
A
Site 28
S346
V
L
K
H
L
R
A
S
M
K
K
L
T
R
K
Site 29
S368
A
K
P
E
Q
G
S
S
A
S
R
P
V
P
A
Site 30
S370
P
E
Q
G
S
S
A
S
R
P
V
P
A
S
R
Site 31
S376
A
S
R
P
V
P
A
S
R
G
G
K
T
L
C
Site 32
T381
P
A
S
R
G
G
K
T
L
C
K
G
D
R
Q
Site 33
S403
W
F
P
R
P
I
W
S
A
S
P
P
R
A
P
Site 34
S405
P
R
P
I
W
S
A
S
P
P
R
A
P
R
S
Site 35
S412
S
P
P
R
A
P
R
S
S
T
P
C
P
G
G
Site 36
S413
P
P
R
A
P
R
S
S
T
P
C
P
G
G
A
Site 37
T414
P
R
A
P
R
S
S
T
P
C
P
G
G
A
V
Site 38
T425
G
G
A
V
R
E
D
T
Y
P
V
G
T
Q
G
Site 39
Y426
G
A
V
R
E
D
T
Y
P
V
G
T
Q
G
V
Site 40
S446
A
Q
G
G
P
Q
G
S
W
R
F
L
Q
W
N
Site 41
T460
N
S
M
P
R
L
P
T
D
L
D
V
E
G
P
Site 42
S484
S
C
W
V
R
A
I
S
Q
E
D
Q
L
A
P
Site 43
S504
H
P
A
E
R
V
R
S
A
F
A
A
P
S
T
Site 44
T511
S
A
F
A
A
P
S
T
D
S
D
Q
G
T
P
Site 45
S513
F
A
A
P
S
T
D
S
D
Q
G
T
P
F
R
Site 46
T517
S
T
D
S
D
Q
G
T
P
F
R
A
R
D
E
Site 47
S531
E
Q
Q
C
A
P
T
S
G
P
C
L
C
G
L
Site 48
S543
C
G
L
H
L
E
S
S
Q
F
P
P
G
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation