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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM115C
Full Name:
Protein FAM115C
Alias:
Protein FAM139A
Type:
Mass (Da):
100906
Number AA:
919
UniProt ID:
A6NFQ2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S64
R
G
R
L
V
V
V
S
H
E
G
Y
L
S
H
Site 2
S70
V
S
H
E
G
Y
L
S
H
T
G
L
A
P
F
Site 3
Y126
P
G
E
P
L
G
V
Y
C
I
N
A
Y
N
D
Site 4
Y157
L
I
G
G
Q
A
W
Y
W
A
S
Q
H
G
P
Site 5
S169
H
G
P
D
K
V
L
S
R
F
P
G
N
K
V
Site 6
T187
A
G
V
Y
F
T
D
T
Y
G
D
R
D
R
F
Site 7
Y188
G
V
Y
F
T
D
T
Y
G
D
R
D
R
F
K
Site 8
T298
R
W
L
A
R
G
Q
T
G
K
V
G
V
N
T
Site 9
S315
K
D
L
C
P
L
L
S
E
H
G
L
Q
C
S
Site 10
S322
S
E
H
G
L
Q
C
S
L
E
P
H
L
N
S
Site 11
T406
A
G
C
F
P
V
P
T
P
E
M
R
S
Y
H
Site 12
Y412
P
T
P
E
M
R
S
Y
H
F
R
K
A
L
S
Site 13
S419
Y
H
F
R
K
A
L
S
Q
F
Q
A
I
L
N
Site 14
S435
E
N
G
N
L
E
K
S
C
L
A
K
L
R
V
Site 15
S460
E
G
V
P
A
Y
I
S
L
H
R
L
L
R
K
Site 16
S472
L
R
K
M
L
R
G
S
G
L
P
A
V
S
R
Site 17
S478
G
S
G
L
P
A
V
S
R
E
N
P
V
A
S
Site 18
S485
S
R
E
N
P
V
A
S
D
S
Y
E
A
A
V
Site 19
S487
E
N
P
V
A
S
D
S
Y
E
A
A
V
L
S
Site 20
T504
T
G
L
A
H
S
G
T
D
C
S
Q
L
A
Q
Site 21
S507
A
H
S
G
T
D
C
S
Q
L
A
Q
G
L
G
Site 22
T517
A
Q
G
L
G
T
W
T
C
S
S
S
L
Y
P
Site 23
S519
G
L
G
T
W
T
C
S
S
S
L
Y
P
S
K
Site 24
S520
L
G
T
W
T
C
S
S
S
L
Y
P
S
K
H
Site 25
S521
G
T
W
T
C
S
S
S
L
Y
P
S
K
H
P
Site 26
Y523
W
T
C
S
S
S
L
Y
P
S
K
H
P
I
T
Site 27
S525
C
S
S
S
L
Y
P
S
K
H
P
I
T
V
E
Site 28
T530
Y
P
S
K
H
P
I
T
V
E
I
N
G
I
N
Site 29
S560
E
G
Q
N
A
E
V
S
L
S
E
A
A
A
S
Site 30
S562
Q
N
A
E
V
S
L
S
E
A
A
A
S
A
G
Site 31
T582
G
C
H
T
D
D
L
T
K
A
R
K
L
S
R
Site 32
S588
L
T
K
A
R
K
L
S
R
A
P
V
V
T
H
Site 33
S607
D
R
T
E
R
S
V
S
C
L
W
G
G
L
L
Site 34
Y639
R
G
A
V
P
A
P
Y
Y
K
L
G
K
T
S
Site 35
Y640
G
A
V
P
A
P
Y
Y
K
L
G
K
T
S
L
Site 36
S646
Y
Y
K
L
G
K
T
S
L
E
E
W
K
R
Q
Site 37
T774
G
W
E
F
P
P
H
T
T
E
A
T
C
N
L
Site 38
S803
A
Q
A
H
E
A
L
S
P
P
E
R
E
R
R
Site 39
S856
F
A
E
Y
Q
T
L
S
H
L
P
K
D
N
T
Site 40
T863
S
H
L
P
K
D
N
T
G
R
M
N
L
W
V
Site 41
S899
I
Q
K
E
V
A
D
S
L
A
S
L
P
E
W
Site 42
Y914
Q
E
N
P
M
Q
V
Y
L
R
A
R
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation