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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRIT2
Full Name:
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2
Alias:
Leucine-rich repeat-containing protein 22
Type:
Mass (Da):
60168
Number AA:
550
UniProt ID:
A6NDA9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
C
L
P
G
C
T
C
S
E
E
S
F
G
R
T
Site 2
S34
G
C
T
C
S
E
E
S
F
G
R
T
L
Q
C
Site 3
T38
S
E
E
S
F
G
R
T
L
Q
C
T
S
V
S
Site 4
S43
G
R
T
L
Q
C
T
S
V
S
L
G
K
I
P
Site 5
S54
G
K
I
P
G
N
L
S
E
E
F
K
Q
V
R
Site 6
S65
K
Q
V
R
I
E
N
S
P
L
F
E
M
P
Q
Site 7
Y83
I
N
M
S
T
L
E
Y
L
W
L
N
F
N
N
Site 8
S117
L
E
G
N
K
L
C
S
V
P
W
T
A
F
R
Site 9
Y155
Q
F
L
V
S
L
T
Y
L
D
L
S
S
N
R
Site 10
T164
D
L
S
S
N
R
L
T
V
V
S
K
S
V
F
Site 11
Y177
V
F
L
N
W
P
A
Y
Q
K
C
R
Q
P
D
Site 12
T263
S
T
P
S
A
N
I
T
I
R
A
G
Q
N
V
Site 13
S283
A
Q
A
S
P
S
P
S
I
A
W
T
Y
P
L
Site 14
T287
P
S
P
S
I
A
W
T
Y
P
L
S
M
W
R
Site 15
Y288
S
P
S
I
A
W
T
Y
P
L
S
M
W
R
E
Site 16
T300
W
R
E
F
D
V
L
T
S
S
T
G
E
D
T
Site 17
S341
G
K
S
N
L
V
I
S
L
H
V
Q
P
A
Q
Site 18
S355
Q
A
L
H
A
P
D
S
L
S
I
P
S
E
G
Site 19
S357
L
H
A
P
D
S
L
S
I
P
S
E
G
N
A
Site 20
Y365
I
P
S
E
G
N
A
Y
I
D
L
R
V
V
K
Site 21
Y397
K
E
E
W
F
T
L
Y
I
A
S
D
E
A
F
Site 22
Y429
D
L
L
P
G
T
K
Y
E
A
C
L
S
L
E
Site 23
S434
T
K
Y
E
A
C
L
S
L
E
G
Q
P
P
H
Site 24
S508
L
H
R
R
K
A
P
S
C
T
P
A
A
P
Q
Site 25
T510
R
R
K
A
P
S
C
T
P
A
A
P
Q
S
K
Site 26
S516
C
T
P
A
A
P
Q
S
K
D
G
S
F
R
E
Site 27
S520
A
P
Q
S
K
D
G
S
F
R
E
H
P
A
V
Site 28
T537
D
G
E
G
H
I
D
T
E
G
D
K
E
K
G
Site 29
T546
G
D
K
E
K
G
G
T
E
D
N
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation