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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
USP17L3
Full Name:
Ubiquitin carboxyl-terminal hydrolase 17-like protein 3
Alias:
Deubiquitinating enzyme 17-like protein 3;Ubiquitin thiolesterase 17-like protein 3;Ubiquitin-specific-processing protease 17-like protein 3
Type:
Mass (Da):
59536
Number AA:
530
UniProt ID:
A6NCW0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
G
D
D
S
L
Y
L
G
G
E
W
Q
F
Site 2
S18
E
W
Q
F
N
H
F
S
K
L
T
S
S
R
P
Site 3
S22
N
H
F
S
K
L
T
S
S
R
P
D
A
A
F
Site 4
S23
H
F
S
K
L
T
S
S
R
P
D
A
A
F
A
Site 5
T35
A
F
A
E
I
Q
R
T
S
L
P
E
K
S
P
Site 6
S36
F
A
E
I
Q
R
T
S
L
P
E
K
S
P
L
Site 7
S41
R
T
S
L
P
E
K
S
P
L
S
S
E
T
R
Site 8
S44
L
P
E
K
S
P
L
S
S
E
T
R
V
D
L
Site 9
S45
P
E
K
S
P
L
S
S
E
T
R
V
D
L
C
Site 10
S71
P
R
E
K
L
P
L
S
S
R
R
P
A
A
V
Site 11
S72
R
E
K
L
P
L
S
S
R
R
P
A
A
V
G
Site 12
Y90
Q
N
M
G
N
T
C
Y
E
N
A
S
L
Q
C
Site 13
Y107
Y
T
L
P
L
A
N
Y
M
L
S
R
E
H
S
Site 14
S110
P
L
A
N
Y
M
L
S
R
E
H
S
Q
T
C
Site 15
S114
Y
M
L
S
R
E
H
S
Q
T
C
Q
R
P
K
Site 16
T116
L
S
R
E
H
S
Q
T
C
Q
R
P
K
C
C
Site 17
T191
D
H
H
S
K
D
T
T
L
I
H
Q
I
F
G
Site 18
Y252
E
L
N
G
E
N
A
Y
H
C
G
L
C
L
Q
Site 19
S264
C
L
Q
R
A
P
A
S
N
T
L
T
L
H
T
Site 20
T268
A
P
A
S
N
T
L
T
L
H
T
S
A
K
V
Site 21
Y297
K
L
A
K
N
V
Q
Y
P
E
C
L
D
M
Q
Site 22
Y306
E
C
L
D
M
Q
P
Y
M
S
Q
Q
N
T
G
Site 23
S308
L
D
M
Q
P
Y
M
S
Q
Q
N
T
G
P
L
Site 24
T312
P
Y
M
S
Q
Q
N
T
G
P
L
V
Y
V
L
Site 25
Y338
H
D
G
H
Y
F
S
Y
V
K
A
Q
E
G
Q
Site 26
Y347
K
A
Q
E
G
Q
W
Y
K
M
D
D
A
E
V
Site 27
Y372
Q
Q
A
Y
V
L
F
Y
I
Q
K
S
E
W
E
Site 28
S382
K
S
E
W
E
R
H
S
E
S
V
S
R
G
R
Site 29
S384
E
W
E
R
H
S
E
S
V
S
R
G
R
E
P
Site 30
S386
E
R
H
S
E
S
V
S
R
G
R
E
P
R
A
Site 31
T399
R
A
L
G
A
E
D
T
D
R
R
A
K
Q
G
Site 32
T429
E
H
L
V
E
R
A
T
Q
E
S
T
L
D
H
Site 33
S432
V
E
R
A
T
Q
E
S
T
L
D
H
W
K
F
Site 34
T446
F
L
Q
E
Q
N
K
T
K
P
E
F
N
V
G
Site 35
Y471
L
V
I
H
Q
S
K
Y
K
C
G
M
K
N
H
Site 36
S485
H
H
P
E
Q
Q
S
S
L
L
N
L
S
S
T
Site 37
S490
Q
S
S
L
L
N
L
S
S
T
T
R
T
D
Q
Site 38
S491
S
S
L
L
N
L
S
S
T
T
R
T
D
Q
E
Site 39
T492
S
L
L
N
L
S
S
T
T
R
T
D
Q
E
S
Site 40
T495
N
L
S
S
T
T
R
T
D
Q
E
S
M
N
T
Site 41
S499
T
T
R
T
D
Q
E
S
M
N
T
G
T
L
A
Site 42
T502
T
D
Q
E
S
M
N
T
G
T
L
A
S
L
Q
Site 43
S507
M
N
T
G
T
L
A
S
L
Q
G
R
T
R
R
Site 44
S522
A
K
G
K
N
K
H
S
K
R
A
L
L
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation