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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMB11
Full Name:
Proteasome subunit beta type-11
Alias:
Proteasome subunit beta-5t
Type:
Protease
Mass (Da):
32530
Number AA:
300
UniProt ID:
A5LHX3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005839
Uniprot
OncoNet
Molecular Function:
GO:0004298
PhosphoSite+
KinaseNET
Biological Process:
GO:0051603
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
Q
D
V
C
K
W
Q
S
P
D
T
Q
G
P
S
Site 2
T14
C
K
W
Q
S
P
D
T
Q
G
P
S
P
H
L
Site 3
S18
S
P
D
T
Q
G
P
S
P
H
L
P
R
A
G
Site 4
T37
P
R
G
C
D
P
Q
T
F
L
Q
I
H
G
P
Site 5
T50
G
P
R
L
A
H
G
T
T
T
L
A
F
R
F
Site 6
S73
D
T
R
S
S
C
G
S
Y
V
A
C
P
A
S
Site 7
Y74
T
R
S
S
C
G
S
Y
V
A
C
P
A
S
C
Site 8
T93
V
H
Q
H
L
L
G
T
T
S
G
T
S
A
D
Site 9
S95
Q
H
L
L
G
T
T
S
G
T
S
A
D
C
A
Site 10
T103
G
T
S
A
D
C
A
T
W
Y
R
V
L
Q
R
Site 11
Y105
S
A
D
C
A
T
W
Y
R
V
L
Q
R
E
L
Site 12
S124
L
R
E
G
Q
L
P
S
V
A
S
A
A
K
L
Site 13
S137
K
L
L
S
A
M
M
S
Q
Y
R
G
L
D
L
Site 14
Y139
L
S
A
M
M
S
Q
Y
R
G
L
D
L
C
V
Site 15
Y162
R
S
G
P
E
L
F
Y
V
Y
S
D
G
T
R
Site 16
S165
P
E
L
F
Y
V
Y
S
D
G
T
R
L
Q
G
Site 17
S176
R
L
Q
G
D
I
F
S
V
G
S
G
S
P
Y
Site 18
S179
G
D
I
F
S
V
G
S
G
S
P
Y
A
Y
G
Site 19
Y183
S
V
G
S
G
S
P
Y
A
Y
G
V
L
D
R
Site 20
Y185
G
S
G
S
P
Y
A
Y
G
V
L
D
R
G
Y
Site 21
Y192
Y
G
V
L
D
R
G
Y
R
Y
D
M
S
T
Q
Site 22
S197
R
G
Y
R
Y
D
M
S
T
Q
E
A
Y
A
L
Site 23
T198
G
Y
R
Y
D
M
S
T
Q
E
A
Y
A
L
A
Site 24
T213
R
C
A
V
A
H
A
T
H
R
D
A
Y
S
G
Site 25
Y218
H
A
T
H
R
D
A
Y
S
G
G
S
V
D
L
Site 26
S222
R
D
A
Y
S
G
G
S
V
D
L
F
H
V
R
Site 27
S231
D
L
F
H
V
R
E
S
G
W
E
H
V
S
R
Site 28
S237
E
S
G
W
E
H
V
S
R
S
D
A
C
V
L
Site 29
S261
P
E
P
E
E
D
A
S
H
A
H
P
E
P
A
Site 30
S280
A
A
E
D
R
E
L
S
V
G
P
G
E
V
T
Site 31
T287
S
V
G
P
G
E
V
T
P
G
D
S
R
M
P
Site 32
S291
G
E
V
T
P
G
D
S
R
M
P
A
G
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation