KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DYTN
Full Name:
Dystrotelin
Alias:
Type:
Mass (Da):
65320
Number AA:
578
UniProt ID:
A2CJ06
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
D
K
Q
D
A
L
N
S
I
E
N
S
I
Y
R
Site 2
S15
A
L
N
S
I
E
N
S
I
Y
R
T
A
F
K
Site 3
Y17
N
S
I
E
N
S
I
Y
R
T
A
F
K
L
Q
Site 4
T19
I
E
N
S
I
Y
R
T
A
F
K
L
Q
S
V
Site 5
S48
Q
Q
V
L
L
R
P
S
F
W
E
A
R
K
H
Site 6
S56
F
W
E
A
R
K
H
S
L
S
V
Q
Q
L
S
Site 7
S58
E
A
R
K
H
S
L
S
V
Q
Q
L
S
Q
A
Site 8
S121
L
I
T
L
S
G
D
S
P
L
S
K
Y
R
A
Site 9
S124
L
S
G
D
S
P
L
S
K
Y
R
A
L
F
Q
Site 10
Y126
G
D
S
P
L
S
K
Y
R
A
L
F
Q
L
Y
Site 11
Y133
Y
R
A
L
F
Q
L
Y
A
E
N
S
R
G
G
Site 12
S137
F
Q
L
Y
A
E
N
S
R
G
G
Y
D
S
G
Site 13
Y141
A
E
N
S
R
G
G
Y
D
S
G
P
R
M
T
Site 14
S143
N
S
R
G
G
Y
D
S
G
P
R
M
T
R
R
Site 15
T148
Y
D
S
G
P
R
M
T
R
R
V
L
R
K
L
Site 16
T157
R
V
L
R
K
L
L
T
D
L
Q
Q
I
P
T
Site 17
T164
T
D
L
Q
Q
I
P
T
F
V
G
E
S
R
A
Site 18
S177
R
A
L
C
P
V
E
S
A
T
R
S
C
F
Q
Site 19
S181
P
V
E
S
A
T
R
S
C
F
Q
G
V
L
S
Site 20
S188
S
C
F
Q
G
V
L
S
P
A
I
K
E
E
K
Site 21
S198
I
K
E
E
K
F
L
S
W
V
Q
S
E
P
P
Site 22
S217
L
P
T
C
H
R
L
S
A
A
E
R
V
T
H
Site 23
T223
L
S
A
A
E
R
V
T
H
P
A
R
C
T
L
Site 24
S262
C
F
L
S
G
L
H
S
K
S
H
Q
K
S
H
Site 25
S264
L
S
G
L
H
S
K
S
H
Q
K
S
H
P
V
Site 26
T290
N
T
K
L
L
F
R
T
L
R
N
N
L
L
Q
Site 27
S346
K
L
Q
A
I
Y
T
S
Q
E
E
R
I
C
R
Site 28
T356
E
R
I
C
R
F
E
T
R
I
H
K
L
K
T
Site 29
T363
T
R
I
H
K
L
K
T
N
Q
D
S
L
W
T
Site 30
S367
K
L
K
T
N
Q
D
S
L
W
T
K
L
Q
Q
Site 31
T370
T
N
Q
D
S
L
W
T
K
L
Q
Q
I
R
R
Site 32
S389
R
L
Q
P
P
G
P
S
S
S
S
F
Q
N
V
Site 33
S390
L
Q
P
P
G
P
S
S
S
S
F
Q
N
V
G
Site 34
S391
Q
P
P
G
P
S
S
S
S
F
Q
N
V
G
N
Site 35
S392
P
P
G
P
S
S
S
S
F
Q
N
V
G
N
K
Site 36
S403
V
G
N
K
V
D
H
S
S
T
E
K
V
P
K
Site 37
S404
G
N
K
V
D
H
S
S
T
E
K
V
P
K
G
Site 38
Y414
K
V
P
K
G
G
D
Y
L
Q
I
K
N
A
T
Site 39
T426
N
A
T
E
D
A
S
T
G
E
P
L
P
K
L
Site 40
S439
K
L
D
E
V
D
R
S
H
R
S
H
T
N
A
Site 41
T444
D
R
S
H
R
S
H
T
N
A
E
H
A
L
R
Site 42
S455
H
A
L
R
N
P
E
S
P
E
T
T
L
H
S
Site 43
T458
R
N
P
E
S
P
E
T
T
L
H
S
T
R
A
Site 44
T459
N
P
E
S
P
E
T
T
L
H
S
T
R
A
Q
Site 45
S462
S
P
E
T
T
L
H
S
T
R
A
Q
S
Q
T
Site 46
S467
L
H
S
T
R
A
Q
S
Q
T
Q
K
M
P
Q
Site 47
T469
S
T
R
A
Q
S
Q
T
Q
K
M
P
Q
K
V
Site 48
S478
K
M
P
Q
K
V
I
S
A
L
P
S
Y
Q
E
Site 49
S482
K
V
I
S
A
L
P
S
Y
Q
E
G
L
K
Q
Site 50
Y483
V
I
S
A
L
P
S
Y
Q
E
G
L
K
Q
D
Site 51
T542
M
D
A
F
N
L
E
T
P
S
G
P
E
S
S
Site 52
S544
A
F
N
L
E
T
P
S
G
P
E
S
S
V
N
Site 53
S548
E
T
P
S
G
P
E
S
S
V
N
M
D
L
Y
Site 54
S549
T
P
S
G
P
E
S
S
V
N
M
D
L
Y
S
Site 55
Y555
S
S
V
N
M
D
L
Y
S
G
A
Q
R
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation