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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIPSL
Full Name:
Putative PIP5K1A and PSMD4-like protein
Alias:
PSMD4P2
Type:
Uncharacterized cytoplasm protein
Mass (Da):
95048
Number AA:
862
UniProt ID:
A2A3N6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0016307
PhosphoSite+
KinaseNET
Biological Process:
GO:0046488
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
S
E
V
P
Y
A
S
G
M
P
I
K
K
I
Site 2
S20
I
K
K
I
G
H
R
S
V
D
S
S
G
G
T
Site 3
S23
I
G
H
R
S
V
D
S
S
G
G
T
T
S
S
Site 4
S24
G
H
R
S
V
D
S
S
G
G
T
T
S
S
A
Site 5
T27
S
V
D
S
S
G
G
T
T
S
S
A
L
K
G
Site 6
S30
S
S
G
G
T
T
S
S
A
L
K
G
A
I
Q
Site 7
S46
G
I
T
H
T
V
G
S
L
S
T
K
P
E
S
Site 8
S48
T
H
T
V
G
S
L
S
T
K
P
E
S
D
V
Site 9
S53
S
L
S
T
K
P
E
S
D
V
L
M
Q
D
F
Site 10
S70
V
E
S
I
F
F
P
S
E
G
S
N
L
T
P
Site 11
T76
P
S
E
G
S
N
L
T
P
A
H
H
Y
N
A
Site 12
T88
Y
N
A
F
R
F
K
T
Y
A
P
V
A
F
R
Site 13
Y89
N
A
F
R
F
K
T
Y
A
P
V
A
F
R
Y
Site 14
Y108
F
G
I
R
P
D
D
Y
L
Y
S
L
C
S
E
Site 15
Y110
I
R
P
D
D
Y
L
Y
S
L
C
S
E
P
L
Site 16
S111
R
P
D
D
Y
L
Y
S
L
C
S
E
P
L
I
Site 17
S128
C
S
S
G
A
S
G
S
L
F
Y
V
S
S
D
Site 18
Y131
G
A
S
G
S
L
F
Y
V
S
S
D
D
E
F
Site 19
T142
D
D
E
F
I
V
K
T
V
R
H
K
E
A
E
Site 20
Y158
L
Q
K
L
L
P
G
Y
Y
I
N
L
N
Q
N
Site 21
T168
N
L
N
Q
N
P
R
T
L
L
P
K
F
Y
G
Site 22
Y177
L
P
K
F
Y
G
L
Y
C
V
Q
T
G
G
K
Site 23
Y205
S
V
K
M
H
I
K
Y
D
L
K
G
S
T
Y
Site 24
S210
I
K
Y
D
L
K
G
S
T
Y
R
R
R
A
S
Site 25
T211
K
Y
D
L
K
G
S
T
Y
R
R
R
A
S
Q
Site 26
Y212
Y
D
L
K
G
S
T
Y
R
R
R
A
S
Q
K
Site 27
S217
S
T
Y
R
R
R
A
S
Q
K
E
R
E
K
P
Site 28
T227
E
R
E
K
P
L
P
T
F
K
D
L
D
F
L
Site 29
S288
H
A
Q
R
E
P
L
S
S
E
T
Q
Y
S
V
Site 30
S289
A
Q
R
E
P
L
S
S
E
T
Q
Y
S
V
D
Site 31
Y293
P
L
S
S
E
T
Q
Y
S
V
D
T
R
R
P
Site 32
S294
L
S
S
E
T
Q
Y
S
V
D
T
R
R
P
A
Site 33
T297
E
T
Q
Y
S
V
D
T
R
R
P
A
P
Q
K
Site 34
Y307
P
A
P
Q
K
A
L
Y
S
T
A
M
E
S
I
Site 35
S308
A
P
Q
K
A
L
Y
S
T
A
M
E
S
I
Q
Site 36
T323
G
E
A
R
R
G
G
T
M
E
T
D
D
H
M
Site 37
S338
G
G
I
P
A
R
N
S
K
G
E
R
L
L
L
Site 38
T375
A
L
I
H
D
G
D
T
V
S
V
H
R
P
G
Site 39
Y384
S
V
H
R
P
G
F
Y
A
E
W
F
Q
R
F
Site 40
S405
K
K
I
P
L
K
P
S
P
S
K
K
L
R
S
Site 41
S407
I
P
L
K
P
S
P
S
K
K
L
R
S
G
S
Site 42
S412
S
P
S
K
K
L
R
S
G
S
S
F
S
Q
R
Site 43
S414
S
K
K
L
R
S
G
S
S
F
S
Q
R
A
G
Site 44
S415
K
K
L
R
S
G
S
S
F
S
Q
R
A
G
S
Site 45
S417
L
R
S
G
S
S
F
S
Q
R
A
G
S
S
G
Site 46
S422
S
F
S
Q
R
A
G
S
S
G
N
S
C
I
T
Site 47
S426
R
A
G
S
S
G
N
S
C
I
T
Y
Q
P
L
Site 48
T429
S
S
G
N
S
C
I
T
Y
Q
P
L
V
S
G
Site 49
Y430
S
G
N
S
C
I
T
Y
Q
P
L
V
S
G
E
Site 50
T463
C
P
D
V
L
P
Q
T
P
P
L
E
E
I
S
Site 51
S470
T
P
P
L
E
E
I
S
E
G
S
P
T
P
D
Site 52
S473
L
E
E
I
S
E
G
S
P
T
P
D
P
S
F
Site 53
T475
E
I
S
E
G
S
P
T
P
D
P
S
F
S
P
Site 54
S479
G
S
P
T
P
D
P
S
F
S
P
L
V
E
E
Site 55
S481
P
T
P
D
P
S
F
S
P
L
V
E
E
T
L
Site 56
T493
E
T
L
Q
M
L
T
T
S
V
D
N
S
E
Y
Site 57
S494
T
L
Q
M
L
T
T
S
V
D
N
S
E
Y
M
Site 58
S498
L
T
T
S
V
D
N
S
E
Y
M
G
N
G
D
Site 59
Y500
T
S
V
D
N
S
E
Y
M
G
N
G
D
F
L
Site 60
T520
A
Q
Q
D
A
V
N
T
V
C
H
S
K
T
R
Site 61
S524
A
V
N
T
V
C
H
S
K
T
R
S
N
P
E
Site 62
S528
V
C
H
S
K
T
R
S
N
P
E
N
N
V
G
Site 63
T548
N
D
C
E
V
L
T
T
L
T
P
D
T
G
R
Site 64
S558
P
D
T
G
R
I
L
S
K
L
H
T
V
Q
P
Site 65
T562
R
I
L
S
K
L
H
T
V
Q
P
K
G
K
I
Site 66
T635
F
G
E
E
E
V
N
T
E
K
L
T
A
F
V
Site 67
S653
N
G
K
D
G
T
G
S
H
L
V
T
V
P
P
Site 68
S670
S
L
A
D
A
L
I
S
F
P
I
L
A
G
E
Site 69
T735
A
A
E
A
G
I
A
T
T
G
T
E
D
S
D
Site 70
S741
A
T
T
G
T
E
D
S
D
D
A
L
L
K
M
Site 71
S751
A
L
L
K
M
T
I
S
Q
Q
E
F
G
H
T
Site 72
T758
S
Q
Q
E
F
G
H
T
G
L
P
D
L
S
S
Site 73
S764
H
T
G
L
P
D
L
S
S
M
T
E
E
E
K
Site 74
S765
T
G
L
P
D
L
S
S
M
T
E
E
E
K
I
Site 75
S796
E
S
A
D
I
D
A
S
S
A
M
D
T
S
E
Site 76
S797
S
A
D
I
D
A
S
S
A
M
D
T
S
E
P
Site 77
T801
D
A
S
S
A
M
D
T
S
E
P
A
K
E
E
Site 78
S802
A
S
S
A
M
D
T
S
E
P
A
K
E
E
D
Site 79
Y811
P
A
K
E
E
D
D
Y
D
V
M
Q
D
P
E
Site 80
S822
Q
D
P
E
F
L
Q
S
V
L
E
N
L
P
G
Site 81
S843
A
I
R
N
A
V
G
S
L
A
S
Q
A
T
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation