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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD18B
Full Name:
Ankyrin repeat domain-containing protein 18B
Alias:
Type:
Mass (Da):
118231
Number AA:
1011
UniProt ID:
A2A2Z9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
R
K
L
L
S
F
G
R
R
L
G
Q
Site 2
S17
R
L
G
Q
A
L
L
S
S
M
D
Q
E
Y
A
Site 3
S18
L
G
Q
A
L
L
S
S
M
D
Q
E
Y
A
G
Site 4
Y23
L
S
S
M
D
Q
E
Y
A
G
R
G
Y
H
I
Site 5
Y28
Q
E
Y
A
G
R
G
Y
H
I
R
D
W
E
L
Site 6
T55
A
E
V
E
H
C
L
T
R
R
F
R
D
L
D
Site 7
T70
V
R
D
R
K
D
R
T
V
L
H
L
A
C
A
Site 8
T103
I
C
D
R
L
N
R
T
P
L
M
K
A
V
H
Site 9
Y133
N
P
N
I
K
D
I
Y
G
N
T
A
L
H
Y
Site 10
Y140
Y
G
N
T
A
L
H
Y
A
V
Y
N
E
G
T
Site 11
S148
A
V
Y
N
E
G
T
S
L
A
E
R
L
L
S
Site 12
S155
S
L
A
E
R
L
L
S
H
H
A
N
I
E
A
Site 13
S177
P
L
L
F
A
I
N
S
R
R
Q
H
M
V
E
Site 14
Y239
F
G
Q
T
A
E
D
Y
A
F
C
C
D
L
R
Site 15
S315
K
Q
E
R
L
E
R
S
E
N
K
Q
P
Q
D
Site 16
S323
E
N
K
Q
P
Q
D
S
Q
S
Y
G
K
K
K
Site 17
S325
K
Q
P
Q
D
S
Q
S
Y
G
K
K
K
D
E
Site 18
Y351
A
M
L
K
E
E
L
Y
A
I
K
N
D
S
L
Site 19
S357
L
Y
A
I
K
N
D
S
L
R
K
E
K
K
Y
Site 20
Y364
S
L
R
K
E
K
K
Y
I
Q
E
I
K
S
I
Site 21
S370
K
Y
I
Q
E
I
K
S
I
T
E
I
N
A
N
Site 22
S381
I
N
A
N
F
E
K
S
V
R
L
N
E
E
M
Site 23
T390
R
L
N
E
E
M
I
T
K
K
V
A
Q
Y
S
Site 24
S412
A
E
N
A
R
L
N
S
K
L
E
K
E
K
H
Site 25
S430
R
L
E
A
E
V
E
S
L
H
S
N
L
A
T
Site 26
T437
S
L
H
S
N
L
A
T
A
I
N
E
Y
N
E
Site 27
S462
L
W
R
A
D
D
V
S
R
H
E
T
M
G
S
Site 28
T466
D
D
V
S
R
H
E
T
M
G
S
N
I
S
Q
Site 29
S469
S
R
H
E
T
M
G
S
N
I
S
Q
L
T
D
Site 30
T494
K
A
R
V
K
F
N
T
L
K
G
K
L
R
E
Site 31
T502
L
K
G
K
L
R
E
T
R
D
A
L
R
E
K
Site 32
T510
R
D
A
L
R
E
K
T
L
A
L
E
S
V
Q
Site 33
S542
P
N
G
E
A
K
E
S
Q
S
I
G
K
Q
N
Site 34
S551
S
I
G
K
Q
N
S
S
E
E
R
I
R
Q
R
Site 35
Y609
N
K
E
L
M
N
E
Y
N
Y
L
K
E
K
L
Site 36
Y611
E
L
M
N
E
Y
N
Y
L
K
E
K
L
L
Q
Site 37
S645
V
D
H
L
K
K
F
S
M
S
E
S
P
L
E
Site 38
S647
H
L
K
K
F
S
M
S
E
S
P
L
E
G
T
Site 39
S649
K
K
F
S
M
S
E
S
P
L
E
G
T
S
H
Site 40
T654
S
E
S
P
L
E
G
T
S
H
C
H
I
N
L
Site 41
S655
E
S
P
L
E
G
T
S
H
C
H
I
N
L
D
Site 42
T664
C
H
I
N
L
D
E
T
W
T
S
K
K
K
L
Site 43
S667
N
L
D
E
T
W
T
S
K
K
K
L
F
Q
V
Site 44
Y697
E
L
I
S
L
L
N
Y
T
A
D
Q
I
R
K
Site 45
T714
R
E
L
E
E
E
A
T
G
Y
K
K
C
L
E
Site 46
Y716
L
E
E
E
A
T
G
Y
K
K
C
L
E
M
T
Site 47
T743
S
C
H
G
D
L
N
T
D
Q
L
K
M
D
I
Site 48
S771
A
E
K
E
A
V
S
S
K
C
V
N
L
A
K
Site 49
T816
E
K
V
L
N
L
K
T
H
M
E
K
D
M
V
Site 50
S833
G
K
V
Q
E
Y
K
S
E
L
D
E
R
A
M
Site 51
T869
E
Q
L
N
K
D
N
T
A
S
L
K
K
K
E
Site 52
S871
L
N
K
D
N
T
A
S
L
K
K
K
E
L
T
Site 53
T878
S
L
K
K
K
E
L
T
L
K
D
V
E
C
K
Site 54
T891
C
K
F
S
K
M
K
T
A
Y
E
D
V
T
T
Site 55
Y893
F
S
K
M
K
T
A
Y
E
D
V
T
T
E
L
Site 56
T897
K
T
A
Y
E
D
V
T
T
E
L
E
E
Y
K
Site 57
T898
T
A
Y
E
D
V
T
T
E
L
E
E
Y
K
E
Site 58
Y903
V
T
T
E
L
E
E
Y
K
E
A
F
A
V
A
Site 59
S916
V
A
L
K
A
N
S
S
M
S
E
K
I
T
K
Site 60
S918
L
K
A
N
S
S
M
S
E
K
I
T
K
S
D
Site 61
T922
S
S
M
S
E
K
I
T
K
S
D
K
K
I
A
Site 62
S924
M
S
E
K
I
T
K
S
D
K
K
I
A
V
I
Site 63
Y944
M
E
K
E
R
M
E
Y
F
L
S
T
L
P
M
Site 64
S947
E
R
M
E
Y
F
L
S
T
L
P
M
R
P
D
Site 65
T948
R
M
E
Y
F
L
S
T
L
P
M
R
P
D
P
Site 66
S965
P
C
V
E
N
L
N
S
I
E
L
N
R
K
Y
Site 67
Y972
S
I
E
L
N
R
K
Y
I
P
K
M
A
I
R
Site 68
T982
K
M
A
I
R
I
P
T
S
N
P
Q
T
S
N
Site 69
S983
M
A
I
R
I
P
T
S
N
P
Q
T
S
N
N
Site 70
T987
I
P
T
S
N
P
Q
T
S
N
N
C
K
N
S
Site 71
S988
P
T
S
N
P
Q
T
S
N
N
C
K
N
S
L
Site 72
S994
T
S
N
N
C
K
N
S
L
T
E
L
L
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation