KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZC3H12D
Full Name:
Probable ribonuclease ZC3H12D
Alias:
MCP-induced protein 4;Zinc finger CCCH domain-containing protein 12D;p34
Type:
Mass (Da):
58078
Number AA:
527
UniProt ID:
A2A288
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
E
F
F
Q
K
L
G
Y
D
R
E
D
V
L
R
Site 2
S45
Q
E
L
I
R
T
G
S
R
P
G
A
L
E
H
Site 3
S63
P
R
L
V
P
R
G
S
C
G
V
P
D
S
A
Site 4
S69
G
S
C
G
V
P
D
S
A
Q
R
G
P
G
T
Site 5
T84
A
L
E
E
D
F
R
T
L
A
S
S
L
R
P
Site 6
S102
D
G
S
N
V
A
M
S
H
G
N
K
E
T
F
Site 7
T108
M
S
H
G
N
K
E
T
F
S
C
R
G
I
K
Site 8
S110
H
G
N
K
E
T
F
S
C
R
G
I
K
L
A
Site 9
T127
W
F
R
D
R
G
H
T
Y
I
K
V
F
V
P
Site 10
Y128
F
R
D
R
G
H
T
Y
I
K
V
F
V
P
S
Site 11
S135
Y
I
K
V
F
V
P
S
W
R
K
D
P
P
R
Site 12
T145
K
D
P
P
R
A
D
T
P
I
R
E
Q
H
V
Site 13
T165
R
Q
A
V
L
V
Y
T
P
S
R
K
V
H
G
Site 14
S167
A
V
L
V
Y
T
P
S
R
K
V
H
G
K
R
Site 15
Y178
H
G
K
R
L
V
C
Y
D
D
R
Y
I
V
K
Site 16
Y182
L
V
C
Y
D
D
R
Y
I
V
K
V
A
Y
E
Site 17
S196
E
Q
D
G
V
I
V
S
N
D
N
Y
R
D
L
Site 18
Y200
V
I
V
S
N
D
N
Y
R
D
L
Q
S
E
N
Site 19
S222
E
Q
R
L
L
M
F
S
F
V
N
D
R
F
M
Site 20
S241
P
L
G
R
H
G
P
S
L
S
N
F
L
S
R
Site 21
S243
G
R
H
G
P
S
L
S
N
F
L
S
R
K
P
Site 22
S247
P
S
L
S
N
F
L
S
R
K
P
K
P
P
E
Site 23
Y268
P
Y
G
K
K
C
T
Y
G
I
K
C
K
F
Y
Site 24
T295
A
D
E
L
R
A
K
T
G
A
R
P
G
A
G
Site 25
S315
P
P
R
A
P
G
G
S
A
G
A
R
A
A
P
Site 26
S329
P
R
E
P
F
A
H
S
L
P
P
A
R
G
S
Site 27
S336
S
L
P
P
A
R
G
S
P
D
L
A
A
L
R
Site 28
S347
A
A
L
R
G
S
F
S
R
L
A
F
S
D
D
Site 29
S352
S
F
S
R
L
A
F
S
D
D
L
G
P
L
G
Site 30
T370
P
V
P
A
C
S
L
T
P
R
L
G
G
P
D
Site 31
S380
L
G
G
P
D
W
V
S
A
G
G
R
V
P
G
Site 32
S390
G
R
V
P
G
P
L
S
L
P
S
P
E
S
Q
Site 33
S393
P
G
P
L
S
L
P
S
P
E
S
Q
F
S
P
Site 34
S396
L
S
L
P
S
P
E
S
Q
F
S
P
G
D
L
Site 35
S399
P
S
P
E
S
Q
F
S
P
G
D
L
P
P
P
Site 36
S428
D
L
H
G
D
L
L
S
P
R
R
P
P
D
D
Site 37
S443
P
W
A
R
P
P
R
S
D
R
F
P
G
R
S
Site 38
S450
S
D
R
F
P
G
R
S
V
W
A
E
P
A
W
Site 39
S466
D
G
A
T
G
G
L
S
V
Y
A
T
E
D
D
Site 40
T470
G
G
L
S
V
Y
A
T
E
D
D
E
G
D
A
Site 41
S487
R
A
R
I
A
L
Y
S
V
F
P
R
D
Q
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation