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Updated November 2019
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Protein Info
Short Name:
FAM22F
Full Name:
Protein FAM22F
Alias:
Type:
Mass (Da):
80770
Number AA:
756
UniProt ID:
A1L443
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S74
G
Q
D
G
R
G
P
S
G
A
G
A
S
N
V
Site 2
S79
G
P
S
G
A
G
A
S
N
V
F
V
Q
M
R
Site 3
S152
Q
A
C
E
G
G
W
S
H
G
L
P
L
P
P
Site 4
S171
A
Q
V
A
P
I
V
S
P
G
N
A
R
P
W
Site 5
S187
Q
G
A
H
G
E
G
S
L
A
P
S
Q
A
K
Site 6
S191
G
E
G
S
L
A
P
S
Q
A
K
A
R
P
D
Site 7
S200
A
K
A
R
P
D
D
S
C
K
P
K
S
V
Y
Site 8
S205
D
D
S
C
K
P
K
S
V
Y
E
N
F
R
L
Site 9
Y207
S
C
K
P
K
S
V
Y
E
N
F
R
L
W
Q
Site 10
Y216
N
F
R
L
W
Q
H
Y
K
P
L
A
R
R
H
Site 11
S227
A
R
R
H
L
P
Q
S
P
D
T
E
A
L
S
Site 12
T230
H
L
P
Q
S
P
D
T
E
A
L
S
C
F
L
Site 13
T250
S
L
A
R
R
K
P
T
M
T
L
E
E
G
L
Site 14
T252
A
R
R
K
P
T
M
T
L
E
E
G
L
W
Q
Site 15
Y276
N
F
D
R
M
I
F
Y
E
M
A
E
K
F
L
Site 16
S304
Q
W
M
K
G
P
Q
S
L
P
P
P
A
P
P
Site 17
Y329
E
V
V
K
Q
P
V
Y
L
P
S
K
D
G
P
Site 18
S332
K
Q
P
V
Y
L
P
S
K
D
G
P
K
A
P
Site 19
Y398
P
P
E
V
V
Q
E
Y
V
D
I
M
E
E
L
Site 20
S408
I
M
E
E
L
L
G
S
H
P
G
D
T
G
E
Site 21
T413
L
G
S
H
P
G
D
T
G
E
P
E
G
Q
R
Site 22
T435
P
Q
E
E
D
G
I
T
S
D
P
G
L
L
S
Site 23
S436
Q
E
E
D
G
I
T
S
D
P
G
L
L
S
Y
Site 24
S442
T
S
D
P
G
L
L
S
Y
I
D
K
L
C
S
Site 25
Y443
S
D
P
G
L
L
S
Y
I
D
K
L
C
S
Q
Site 26
S449
S
Y
I
D
K
L
C
S
Q
E
D
F
V
T
K
Site 27
S471
R
F
L
E
E
L
L
S
P
D
P
Q
M
D
F
Site 28
S482
Q
M
D
F
L
A
L
S
Q
E
L
E
Q
E
E
Site 29
T492
L
E
Q
E
E
G
L
T
L
A
Q
L
V
E
K
Site 30
S503
L
V
E
K
R
L
L
S
L
K
E
K
G
C
G
Site 31
T518
R
A
A
P
R
H
G
T
A
R
L
D
S
S
P
Site 32
S523
H
G
T
A
R
L
D
S
S
P
S
E
F
A
A
Site 33
S524
G
T
A
R
L
D
S
S
P
S
E
F
A
A
G
Site 34
S526
A
R
L
D
S
S
P
S
E
F
A
A
G
Q
E
Site 35
S546
P
D
P
Q
Q
R
V
S
V
E
T
S
P
P
Q
Site 36
T549
Q
Q
R
V
S
V
E
T
S
P
P
Q
T
A
A
Site 37
S550
Q
R
V
S
V
E
T
S
P
P
Q
T
A
A
Q
Site 38
T554
V
E
T
S
P
P
Q
T
A
A
Q
D
P
Q
G
Site 39
T567
Q
G
Q
G
R
V
R
T
G
M
A
R
S
E
D
Site 40
T593
R
L
K
A
V
R
P
T
S
P
P
Q
D
H
R
Site 41
S594
L
K
A
V
R
P
T
S
P
P
Q
D
H
R
P
Site 42
T602
P
P
Q
D
H
R
P
T
C
P
G
L
G
T
K
Site 43
S618
A
L
G
L
P
G
E
S
P
V
K
E
S
H
G
Site 44
S631
H
G
L
A
K
G
S
S
E
E
T
E
L
P
G
Site 45
T634
A
K
G
S
S
E
E
T
E
L
P
G
M
V
Y
Site 46
Y641
T
E
L
P
G
M
V
Y
V
V
G
S
H
H
R
Site 47
S655
R
L
R
P
W
R
L
S
Q
S
P
V
P
S
S
Site 48
S657
R
P
W
R
L
S
Q
S
P
V
P
S
S
G
L
Site 49
S661
L
S
Q
S
P
V
P
S
S
G
L
L
S
P
G
Site 50
S662
S
Q
S
P
V
P
S
S
G
L
L
S
P
G
G
Site 51
S666
V
P
S
S
G
L
L
S
P
G
G
R
G
P
Q
Site 52
S678
G
P
Q
G
A
L
Q
S
P
S
A
Q
K
R
G
Site 53
S680
Q
G
A
L
Q
S
P
S
A
Q
K
R
G
L
S
Site 54
S687
S
A
Q
K
R
G
L
S
P
S
P
S
P
A
S
Site 55
S689
Q
K
R
G
L
S
P
S
P
S
P
A
S
K
S
Site 56
S691
R
G
L
S
P
S
P
S
P
A
S
K
S
K
K
Site 57
S694
S
P
S
P
S
P
A
S
K
S
K
K
R
P
L
Site 58
S696
S
P
S
P
A
S
K
S
K
K
R
P
L
F
G
Site 59
S704
K
K
R
P
L
F
G
S
P
S
P
A
E
K
T
Site 60
S706
R
P
L
F
G
S
P
S
P
A
E
K
T
P
H
Site 61
T711
S
P
S
P
A
E
K
T
P
H
P
G
P
G
L
Site 62
S721
P
G
P
G
L
R
V
S
G
E
Q
S
L
A
W
Site 63
S725
L
R
V
S
G
E
Q
S
L
A
W
G
L
G
G
Site 64
S734
A
W
G
L
G
G
P
S
Q
S
Q
K
R
K
G
Site 65
S736
G
L
G
G
P
S
Q
S
Q
K
R
K
G
D
P
Site 66
S746
R
K
G
D
P
L
A
S
R
R
K
K
K
R
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation