KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LOC130074
Full Name:
Protein FAM168B
Alias:
Putative LOC130074
Type:
Mass (Da):
20306
Number AA:
195
UniProt ID:
A1KXE4
International Prot ID:
IPI00556592
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
N
P
V
Y
S
P
G
S
S
G
V
P
Site 2
S9
N
P
V
Y
S
P
G
S
S
G
V
P
Y
A
N
Site 3
S10
P
V
Y
S
P
G
S
S
G
V
P
Y
A
N
A
Site 4
Y14
P
G
S
S
G
V
P
Y
A
N
A
K
G
I
G
Site 5
S38
A
A
A
A
P
A
Y
S
P
N
M
Y
P
G
A
Site 6
Y42
P
A
Y
S
P
N
M
Y
P
G
A
N
P
T
F
Site 7
T48
M
Y
P
G
A
N
P
T
F
Q
T
G
Y
T
P
Site 8
Y53
N
P
T
F
Q
T
G
Y
T
P
G
T
P
Y
K
Site 9
T54
P
T
F
Q
T
G
Y
T
P
G
T
P
Y
K
V
Site 10
T57
Q
T
G
Y
T
P
G
T
P
Y
K
V
S
C
S
Site 11
Y59
G
Y
T
P
G
T
P
Y
K
V
S
C
S
P
T
Site 12
S62
P
G
T
P
Y
K
V
S
C
S
P
T
S
G
A
Site 13
S64
T
P
Y
K
V
S
C
S
P
T
S
G
A
V
P
Site 14
T66
Y
K
V
S
C
S
P
T
S
G
A
V
P
P
Y
Site 15
S67
K
V
S
C
S
P
T
S
G
A
V
P
P
Y
S
Site 16
Y73
T
S
G
A
V
P
P
Y
S
S
S
P
N
P
Y
Site 17
S74
S
G
A
V
P
P
Y
S
S
S
P
N
P
Y
Q
Site 18
S76
A
V
P
P
Y
S
S
S
P
N
P
Y
Q
T
A
Site 19
Y80
Y
S
S
S
P
N
P
Y
Q
T
A
V
Y
P
V
Site 20
Y85
N
P
Y
Q
T
A
V
Y
P
V
R
S
A
Y
P
Site 21
S89
T
A
V
Y
P
V
R
S
A
Y
P
Q
Q
S
P
Site 22
Y91
V
Y
P
V
R
S
A
Y
P
Q
Q
S
P
Y
A
Site 23
S95
R
S
A
Y
P
Q
Q
S
P
Y
A
Q
Q
G
T
Site 24
Y97
A
Y
P
Q
Q
S
P
Y
A
Q
Q
G
T
Y
Y
Site 25
T102
S
P
Y
A
Q
Q
G
T
Y
Y
T
Q
P
L
Y
Site 26
Y104
Y
A
Q
Q
G
T
Y
Y
T
Q
P
L
Y
A
A
Site 27
Y109
T
Y
Y
T
Q
P
L
Y
A
A
P
P
H
V
I
Site 28
T130
Q
P
N
G
M
P
A
T
V
Y
P
A
P
I
P
Site 29
Y132
N
G
M
P
A
T
V
Y
P
A
P
I
P
P
P
Site 30
T145
P
P
R
G
N
G
V
T
M
G
M
V
A
G
T
Site 31
S166
G
T
L
L
T
A
H
S
P
T
P
V
A
P
H
Site 32
T176
P
V
A
P
H
P
V
T
V
P
T
Y
R
A
P
Site 33
T179
P
H
P
V
T
V
P
T
Y
R
A
P
G
T
P
Site 34
Y180
H
P
V
T
V
P
T
Y
R
A
P
G
T
P
T
Site 35
T185
P
T
Y
R
A
P
G
T
P
T
Y
S
Y
V
P
Site 36
T187
Y
R
A
P
G
T
P
T
Y
S
Y
V
P
P
Q
Site 37
Y188
R
A
P
G
T
P
T
Y
S
Y
V
P
P
Q
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation