KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
REXO1L2P
Full Name:
Putative exonuclease GOR-like protein
Alias:
RNA exonuclease 1 homolog-like 2
Type:
Mass (Da):
64243
Number AA:
583
UniProt ID:
A0PJM3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
P
C
W
F
P
P
G
Y
P
E
A
K
K
V
A
Site 2
S35
A
P
E
F
P
L
P
S
H
Q
P
A
Q
S
F
Site 3
S41
P
S
H
Q
P
A
Q
S
F
G
L
W
V
P
Q
Site 4
Y83
K
M
V
T
E
S
C
Y
F
P
A
Q
R
G
S
Site 5
S90
Y
F
P
A
Q
R
G
S
A
C
R
L
P
A
A
Site 6
T101
L
P
A
A
P
R
L
T
E
R
P
S
G
V
R
Site 7
S105
P
R
L
T
E
R
P
S
G
V
R
I
S
A
P
Site 8
S110
R
P
S
G
V
R
I
S
A
P
R
K
R
K
T
Site 9
T117
S
A
P
R
K
R
K
T
I
A
H
S
S
S
P
Site 10
S121
K
R
K
T
I
A
H
S
S
S
P
C
L
V
T
Site 11
S122
R
K
T
I
A
H
S
S
S
P
C
L
V
T
G
Site 12
S123
K
T
I
A
H
S
S
S
P
C
L
V
T
G
Y
Site 13
T131
P
C
L
V
T
G
Y
T
D
A
K
R
T
R
V
Site 14
T136
G
Y
T
D
A
K
R
T
R
V
A
S
S
S
Q
Site 15
S140
A
K
R
T
R
V
A
S
S
S
Q
R
S
R
G
Site 16
S141
K
R
T
R
V
A
S
S
S
Q
R
S
R
G
S
Site 17
S142
R
T
R
V
A
S
S
S
Q
R
S
R
G
S
K
Site 18
S145
V
A
S
S
S
Q
R
S
R
G
S
K
V
G
R
Site 19
S148
S
S
Q
R
S
R
G
S
K
V
G
R
Q
P
G
Site 20
T157
V
G
R
Q
P
G
K
T
R
N
R
S
G
M
A
Site 21
S161
P
G
K
T
R
N
R
S
G
M
A
C
K
T
T
Site 22
T167
R
S
G
M
A
C
K
T
T
A
T
T
S
S
K
Site 23
T168
S
G
M
A
C
K
T
T
A
T
T
S
S
K
R
Site 24
S172
C
K
T
T
A
T
T
S
S
K
R
I
V
R
R
Site 25
S173
K
T
T
A
T
T
S
S
K
R
I
V
R
R
A
Site 26
S181
K
R
I
V
R
R
A
S
L
P
S
L
S
L
K
Site 27
S184
V
R
R
A
S
L
P
S
L
S
L
K
K
P
I
Site 28
S195
K
K
P
I
I
L
R
S
S
G
C
Q
V
P
T
Site 29
T202
S
S
G
C
Q
V
P
T
V
L
R
R
G
Y
L
Site 30
Y208
P
T
V
L
R
R
G
Y
L
Q
L
F
T
E
E
Site 31
S222
E
C
L
K
F
C
A
S
K
Q
E
A
E
E
K
Site 32
Y238
L
N
E
E
K
V
A
Y
D
C
S
P
N
K
N
Site 33
S241
E
K
V
A
Y
D
C
S
P
N
K
N
R
Y
L
Site 34
Y247
C
S
P
N
K
N
R
Y
L
N
V
V
L
N
T
Site 35
T262
L
K
R
L
K
G
L
T
P
S
S
M
P
G
L
Site 36
S264
R
L
K
G
L
T
P
S
S
M
P
G
L
S
R
Site 37
S265
L
K
G
L
T
P
S
S
M
P
G
L
S
R
A
Site 38
S270
P
S
S
M
P
G
L
S
R
A
A
L
Y
S
R
Site 39
T284
R
L
Q
E
F
L
L
T
Q
D
Q
L
K
E
N
Site 40
Y293
D
Q
L
K
E
N
G
Y
P
F
P
H
P
E
R
Site 41
T308
P
G
G
A
V
L
F
T
G
Q
G
K
G
P
G
Site 42
S317
Q
G
K
G
P
G
D
S
S
C
R
V
C
C
R
Site 43
T327
R
V
C
C
R
C
G
T
E
Y
L
V
S
S
S
Site 44
Y329
C
C
R
C
G
T
E
Y
L
V
S
S
S
G
R
Site 45
S332
C
G
T
E
Y
L
V
S
S
S
G
R
C
V
R
Site 46
S334
T
E
Y
L
V
S
S
S
G
R
C
V
R
D
Q
Site 47
Y345
V
R
D
Q
L
C
Y
Y
H
W
G
R
V
R
S
Site 48
S352
Y
H
W
G
R
V
R
S
S
Q
V
A
G
G
R
Site 49
S353
H
W
G
R
V
R
S
S
Q
V
A
G
G
R
V
Site 50
T364
G
G
R
V
S
Q
Y
T
C
C
A
A
A
P
G
Site 51
S389
V
R
D
G
R
K
E
S
L
D
G
F
V
E
T
Site 52
T396
S
L
D
G
F
V
E
T
F
K
K
E
L
S
R
Site 53
S402
E
T
F
K
K
E
L
S
R
D
A
Y
P
G
I
Site 54
Y406
K
E
L
S
R
D
A
Y
P
G
I
Y
A
L
D
Site 55
Y439
D
A
D
M
R
V
V
Y
D
T
F
V
K
P
D
Site 56
T441
D
M
R
V
V
Y
D
T
F
V
K
P
D
N
E
Site 57
Y452
P
D
N
E
I
V
D
Y
N
T
R
F
S
G
V
Site 58
S457
V
D
Y
N
T
R
F
S
G
V
T
E
A
D
V
Site 59
Y522
P
H
Y
L
G
F
P
Y
K
R
S
L
R
N
L
Site 60
S525
L
G
F
P
Y
K
R
S
L
R
N
L
A
A
D
Site 61
S541
L
A
Q
I
I
Q
D
S
Q
D
G
H
N
S
S
Site 62
S547
D
S
Q
D
G
H
N
S
S
E
D
A
N
A
C
Site 63
S548
S
Q
D
G
H
N
S
S
E
D
A
N
A
C
L
Site 64
S574
Q
I
Q
P
R
H
R
S
A
S
P
A
A
L
A
Site 65
S576
Q
P
R
H
R
S
A
S
P
A
A
L
A
C
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation