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Updated November 2019
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Protein Info
Short Name:
UHRF1BP1L
Full Name:
UHRF1-binding protein 1-like
Alias:
KIAA0701; UH1BL; UHRF1 binding protein 1-like
Type:
Unknown function
Mass (Da):
164198
Number AA:
1464
UniProt ID:
A0JNW5
International Prot ID:
IPI00157895
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
K
Q
I
L
K
H
L
S
R
F
T
K
N
L
S
Site 2
T17
L
K
H
L
S
R
F
T
K
N
L
S
P
D
K
Site 3
S21
S
R
F
T
K
N
L
S
P
D
K
I
N
L
S
Site 4
S28
S
P
D
K
I
N
L
S
T
L
K
G
E
G
E
Site 5
T29
P
D
K
I
N
L
S
T
L
K
G
E
G
E
L
Site 6
S67
K
V
F
C
N
K
A
S
I
R
I
P
W
T
K
Site 7
T73
A
S
I
R
I
P
W
T
K
L
K
T
H
P
I
Site 8
S92
D
K
V
I
M
E
M
S
T
C
E
E
P
R
S
Site 9
S99
S
T
C
E
E
P
R
S
P
N
G
P
S
P
I
Site 10
S104
P
R
S
P
N
G
P
S
P
I
A
T
A
S
G
Site 11
T108
N
G
P
S
P
I
A
T
A
S
G
Q
S
E
Y
Site 12
S110
P
S
P
I
A
T
A
S
G
Q
S
E
Y
G
F
Site 13
S126
E
K
V
V
E
G
I
S
V
S
V
N
S
I
V
Site 14
S131
G
I
S
V
S
V
N
S
I
V
I
R
I
G
A
Site 15
S144
G
A
K
A
F
N
A
S
F
E
L
S
Q
L
R
Site 16
Y153
E
L
S
Q
L
R
I
Y
S
V
N
A
H
W
E
Site 17
T167
E
H
G
D
L
R
F
T
R
I
Q
D
P
Q
R
Site 18
T179
P
Q
R
G
E
V
L
T
F
K
E
I
N
W
Q
Site 19
T195
I
R
I
E
A
D
A
T
Q
S
S
H
L
E
I
Site 20
S198
E
A
D
A
T
Q
S
S
H
L
E
I
M
C
A
Site 21
S214
V
R
L
I
T
N
Q
S
K
I
R
V
T
L
K
Site 22
T219
N
Q
S
K
I
R
V
T
L
K
R
R
L
K
D
Site 23
S259
A
M
V
Q
Y
A
K
S
L
S
E
A
I
E
K
Site 24
S261
V
Q
Y
A
K
S
L
S
E
A
I
E
K
S
T
Site 25
S267
L
S
E
A
I
E
K
S
T
E
Q
R
K
S
M
Site 26
S273
K
S
T
E
Q
R
K
S
M
A
P
E
P
T
Q
Site 27
S281
M
A
P
E
P
T
Q
S
S
T
V
V
A
S
A
Site 28
S282
A
P
E
P
T
Q
S
S
T
V
V
A
S
A
Q
Site 29
T283
P
E
P
T
Q
S
S
T
V
V
A
S
A
Q
Q
Site 30
T293
A
S
A
Q
Q
V
K
T
T
Q
T
S
N
A
P
Site 31
S342
I
H
A
K
E
K
E
S
N
R
R
I
T
G
G
Site 32
T347
K
E
S
N
R
R
I
T
G
G
A
M
Q
L
S
Site 33
Y362
F
T
Q
L
T
I
D
Y
Y
P
Y
H
K
A
G
Site 34
Y363
T
Q
L
T
I
D
Y
Y
P
Y
H
K
A
G
D
Site 35
Y365
L
T
I
D
Y
Y
P
Y
H
K
A
G
D
S
C
Site 36
S414
V
K
D
H
N
V
G
S
P
P
K
S
P
T
H
Site 37
S418
N
V
G
S
P
P
K
S
P
T
H
A
S
P
Q
Site 38
T420
G
S
P
P
K
S
P
T
H
A
S
P
Q
H
T
Site 39
S423
P
K
S
P
T
H
A
S
P
Q
H
T
Q
T
E
Site 40
T427
T
H
A
S
P
Q
H
T
Q
T
E
K
D
Y
P
Site 41
T429
A
S
P
Q
H
T
Q
T
E
K
D
Y
P
L
K
Site 42
Y433
H
T
Q
T
E
K
D
Y
P
L
K
G
T
C
R
Site 43
T438
K
D
Y
P
L
K
G
T
C
R
T
P
S
V
L
Site 44
T441
P
L
K
G
T
C
R
T
P
S
V
L
S
Q
Q
Site 45
S443
K
G
T
C
R
T
P
S
V
L
S
Q
Q
S
K
Site 46
S446
C
R
T
P
S
V
L
S
Q
Q
S
K
A
K
L
Site 47
S449
P
S
V
L
S
Q
Q
S
K
A
K
L
M
S
S
Site 48
Y468
R
L
A
D
F
N
I
Y
Q
V
S
T
A
E
Q
Site 49
S478
S
T
A
E
Q
C
R
S
S
P
K
S
M
I
C
Site 50
S479
T
A
E
Q
C
R
S
S
P
K
S
M
I
C
C
Site 51
Y492
C
C
N
K
K
S
L
Y
L
P
Q
E
M
S
A
Site 52
Y501
P
Q
E
M
S
A
V
Y
I
E
F
T
E
Y
Y
Site 53
Y507
V
Y
I
E
F
T
E
Y
Y
Y
P
D
G
K
D
Site 54
Y508
Y
I
E
F
T
E
Y
Y
Y
P
D
G
K
D
F
Site 55
Y509
I
E
F
T
E
Y
Y
Y
P
D
G
K
D
F
P
Site 56
S519
G
K
D
F
P
I
P
S
P
N
L
Y
S
Q
L
Site 57
Y523
P
I
P
S
P
N
L
Y
S
Q
L
N
A
L
Q
Site 58
S524
I
P
S
P
N
L
Y
S
Q
L
N
A
L
Q
F
Site 59
T532
Q
L
N
A
L
Q
F
T
V
D
E
R
S
I
L
Site 60
S565
V
Y
K
L
N
D
N
S
K
S
D
E
H
V
D
Site 61
S567
K
L
N
D
N
S
K
S
D
E
H
V
D
V
R
Site 62
S590
V
I
P
S
E
V
K
S
E
C
H
Q
D
Q
P
Site 63
S601
Q
D
Q
P
R
A
I
S
I
Q
S
S
E
M
I
Site 64
S605
R
A
I
S
I
Q
S
S
E
M
I
A
T
N
T
Site 65
T610
Q
S
S
E
M
I
A
T
N
T
R
H
C
P
N
Site 66
T639
D
C
D
F
F
S
K
T
Y
T
S
F
P
K
S
Site 67
T641
D
F
F
S
K
T
Y
T
S
F
P
K
S
C
D
Site 68
S642
F
F
S
K
T
Y
T
S
F
P
K
S
C
D
N
Site 69
S646
T
Y
T
S
F
P
K
S
C
D
N
F
N
L
L
Site 70
T677
E
I
Y
K
G
N
I
T
P
Q
L
N
K
N
T
Site 71
Y705
F
S
Q
F
W
I
D
Y
E
G
M
K
S
G
K
Site 72
S710
I
D
Y
E
G
M
K
S
G
K
G
R
P
I
S
Site 73
S717
S
G
K
G
R
P
I
S
F
V
D
S
F
P
L
Site 74
T743
E
S
Q
K
E
P
Q
T
C
N
Q
V
S
L
N
Site 75
S748
P
Q
T
C
N
Q
V
S
L
N
T
S
Q
S
E
Site 76
S752
N
Q
V
S
L
N
T
S
Q
S
E
S
S
D
L
Site 77
S754
V
S
L
N
T
S
Q
S
E
S
S
D
L
A
G
Site 78
S756
L
N
T
S
Q
S
E
S
S
D
L
A
G
R
L
Site 79
Y772
R
K
K
L
L
K
E
Y
Y
S
T
E
S
E
P
Site 80
Y773
K
K
L
L
K
E
Y
Y
S
T
E
S
E
P
L
Site 81
S774
K
L
L
K
E
Y
Y
S
T
E
S
E
P
L
T
Site 82
T775
L
L
K
E
Y
Y
S
T
E
S
E
P
L
T
N
Site 83
S777
K
E
Y
Y
S
T
E
S
E
P
L
T
N
G
G
Site 84
T781
S
T
E
S
E
P
L
T
N
G
G
Q
K
P
S
Site 85
S788
T
N
G
G
Q
K
P
S
S
S
D
T
F
F
R
Site 86
S789
N
G
G
Q
K
P
S
S
S
D
T
F
F
R
F
Site 87
S790
G
G
Q
K
P
S
S
S
D
T
F
F
R
F
S
Site 88
T792
Q
K
P
S
S
S
D
T
F
F
R
F
S
P
S
Site 89
S797
S
D
T
F
F
R
F
S
P
S
S
S
E
A
D
Site 90
S799
T
F
F
R
F
S
P
S
S
S
E
A
D
I
H
Site 91
S800
F
F
R
F
S
P
S
S
S
E
A
D
I
H
L
Site 92
S801
F
R
F
S
P
S
S
S
E
A
D
I
H
L
L
Site 93
T849
R
K
D
V
E
A
V
T
G
S
P
A
S
Q
T
Site 94
S851
D
V
E
A
V
T
G
S
P
A
S
Q
T
S
I
Site 95
S884
D
Q
A
N
T
L
K
S
P
V
S
E
S
V
S
Site 96
S887
N
T
L
K
S
P
V
S
E
S
V
S
P
V
V
Site 97
S889
L
K
S
P
V
S
E
S
V
S
P
V
V
P
D
Site 98
Y897
V
S
P
V
V
P
D
Y
L
P
T
E
N
G
D
Site 99
S907
T
E
N
G
D
F
L
S
S
K
R
K
Q
I
S
Site 100
S908
E
N
G
D
F
L
S
S
K
R
K
Q
I
S
R
Site 101
S922
R
D
I
N
R
I
R
S
V
T
V
N
H
M
S
Site 102
T924
I
N
R
I
R
S
V
T
V
N
H
M
S
D
N
Site 103
S929
S
V
T
V
N
H
M
S
D
N
R
S
M
S
V
Site 104
S933
N
H
M
S
D
N
R
S
M
S
V
D
L
S
H
Site 105
S935
M
S
D
N
R
S
M
S
V
D
L
S
H
I
P
Site 106
S939
R
S
M
S
V
D
L
S
H
I
P
L
K
D
P
Site 107
S951
K
D
P
L
L
F
K
S
A
S
D
T
N
L
Q
Site 108
S953
P
L
L
F
K
S
A
S
D
T
N
L
Q
K
G
Site 109
T955
L
F
K
S
A
S
D
T
N
L
Q
K
G
I
S
Site 110
S962
T
N
L
Q
K
G
I
S
F
M
D
Y
L
S
D
Site 111
Y966
K
G
I
S
F
M
D
Y
L
S
D
K
H
L
G
Site 112
S968
I
S
F
M
D
Y
L
S
D
K
H
L
G
K
I
Site 113
S976
D
K
H
L
G
K
I
S
E
D
E
S
S
G
L
Site 114
S980
G
K
I
S
E
D
E
S
S
G
L
V
Y
K
S
Site 115
S981
K
I
S
E
D
E
S
S
G
L
V
Y
K
S
G
Site 116
Y985
D
E
S
S
G
L
V
Y
K
S
G
S
G
E
I
Site 117
S987
S
S
G
L
V
Y
K
S
G
S
G
E
I
G
S
Site 118
S989
G
L
V
Y
K
S
G
S
G
E
I
G
S
E
T
Site 119
S994
S
G
S
G
E
I
G
S
E
T
S
D
K
K
D
Site 120
T996
S
G
E
I
G
S
E
T
S
D
K
K
D
S
F
Site 121
S997
G
E
I
G
S
E
T
S
D
K
K
D
S
F
Y
Site 122
S1002
E
T
S
D
K
K
D
S
F
Y
T
D
S
S
S
Site 123
Y1004
S
D
K
K
D
S
F
Y
T
D
S
S
S
I
L
Site 124
T1005
D
K
K
D
S
F
Y
T
D
S
S
S
I
L
N
Site 125
S1007
K
D
S
F
Y
T
D
S
S
S
I
L
N
Y
R
Site 126
S1008
D
S
F
Y
T
D
S
S
S
I
L
N
Y
R
E
Site 127
S1009
S
F
Y
T
D
S
S
S
I
L
N
Y
R
E
D
Site 128
Y1013
D
S
S
S
I
L
N
Y
R
E
D
S
N
I
L
Site 129
S1017
I
L
N
Y
R
E
D
S
N
I
L
S
F
D
S
Site 130
S1021
R
E
D
S
N
I
L
S
F
D
S
D
G
N
Q
Site 131
S1024
S
N
I
L
S
F
D
S
D
G
N
Q
N
I
L
Site 132
S1032
D
G
N
Q
N
I
L
S
S
T
L
T
S
K
G
Site 133
S1033
G
N
Q
N
I
L
S
S
T
L
T
S
K
G
N
Site 134
T1036
N
I
L
S
S
T
L
T
S
K
G
N
E
T
I
Site 135
S1037
I
L
S
S
T
L
T
S
K
G
N
E
T
I
E
Site 136
S1045
K
G
N
E
T
I
E
S
I
F
K
A
E
D
L
Site 137
S1060
L
P
E
A
A
S
L
S
E
N
L
D
I
S
K
Site 138
S1066
L
S
E
N
L
D
I
S
K
E
E
T
P
P
V
Site 139
T1070
L
D
I
S
K
E
E
T
P
P
V
R
T
L
K
Site 140
T1075
E
E
T
P
P
V
R
T
L
K
S
Q
S
S
L
Site 141
S1078
P
P
V
R
T
L
K
S
Q
S
S
L
S
G
K
Site 142
S1081
R
T
L
K
S
Q
S
S
L
S
G
K
P
K
E
Site 143
S1083
L
K
S
Q
S
S
L
S
G
K
P
K
E
R
C
Site 144
S1107
S
Y
K
N
M
K
R
S
S
S
Q
M
S
L
D
Site 145
S1108
Y
K
N
M
K
R
S
S
S
Q
M
S
L
D
T
Site 146
S1109
K
N
M
K
R
S
S
S
Q
M
S
L
D
T
I
Site 147
S1112
K
R
S
S
S
Q
M
S
L
D
T
I
S
L
D
Site 148
S1130
L
E
E
Q
L
L
E
S
D
G
S
D
S
H
M
Site 149
S1133
Q
L
L
E
S
D
G
S
D
S
H
M
F
L
E
Site 150
S1135
L
E
S
D
G
S
D
S
H
M
F
L
E
K
G
Site 151
T1148
K
G
N
K
K
N
S
T
T
N
Y
R
G
T
A
Site 152
Y1151
K
K
N
S
T
T
N
Y
R
G
T
A
E
S
V
Site 153
T1154
S
T
T
N
Y
R
G
T
A
E
S
V
N
A
G
Site 154
S1157
N
Y
R
G
T
A
E
S
V
N
A
G
A
N
L
Site 155
Y1167
A
G
A
N
L
Q
N
Y
G
E
T
S
P
D
A
Site 156
S1171
L
Q
N
Y
G
E
T
S
P
D
A
I
S
T
N
Site 157
S1176
E
T
S
P
D
A
I
S
T
N
S
E
G
A
Q
Site 158
T1221
C
L
Q
V
N
Q
V
T
P
D
Q
L
G
N
I
Site 159
Y1233
G
N
I
S
L
R
H
Y
L
C
N
R
P
V
G
Site 160
S1249
D
Q
K
A
V
I
H
S
K
S
S
P
E
I
S
Site 161
S1251
K
A
V
I
H
S
K
S
S
P
E
I
S
L
R
Site 162
S1252
A
V
I
H
S
K
S
S
P
E
I
S
L
R
F
Site 163
S1256
S
K
S
S
P
E
I
S
L
R
F
E
S
G
P
Site 164
T1287
C
H
I
E
N
F
S
T
E
F
L
T
S
S
L
Site 165
S1293
S
T
E
F
L
T
S
S
L
M
N
I
Q
H
F
Site 166
T1305
Q
H
F
L
E
D
E
T
V
A
T
V
M
P
M
Site 167
S1327
K
I
N
L
K
D
D
S
P
R
S
S
T
V
S
Site 168
S1330
L
K
D
D
S
P
R
S
S
T
V
S
L
E
P
Site 169
S1331
K
D
D
S
P
R
S
S
T
V
S
L
E
P
A
Site 170
T1332
D
D
S
P
R
S
S
T
V
S
L
E
P
A
P
Site 171
S1334
S
P
R
S
S
T
V
S
L
E
P
A
P
V
T
Site 172
S1352
D
H
L
V
V
E
R
S
D
D
G
S
F
H
I
Site 173
S1356
V
E
R
S
D
D
G
S
F
H
I
R
D
S
H
Site 174
S1377
D
L
K
E
N
V
K
S
D
S
V
L
L
T
S
Site 175
S1379
K
E
N
V
K
S
D
S
V
L
L
T
S
G
K
Site 176
T1383
K
S
D
S
V
L
L
T
S
G
K
Y
D
L
K
Site 177
S1384
S
D
S
V
L
L
T
S
G
K
Y
D
L
K
K
Site 178
S1394
Y
D
L
K
K
Q
R
S
V
T
Q
A
T
Q
T
Site 179
T1396
L
K
K
Q
R
S
V
T
Q
A
T
Q
T
S
P
Site 180
T1401
S
V
T
Q
A
T
Q
T
S
P
G
V
P
W
P
Site 181
S1402
V
T
Q
A
T
Q
T
S
P
G
V
P
W
P
S
Site 182
S1409
S
P
G
V
P
W
P
S
Q
S
A
N
F
P
E
Site 183
S1411
G
V
P
W
P
S
Q
S
A
N
F
P
E
F
S
Site 184
S1418
S
A
N
F
P
E
F
S
F
D
F
T
R
E
Q
Site 185
T1422
P
E
F
S
F
D
F
T
R
E
Q
L
M
E
E
Site 186
S1432
Q
L
M
E
E
N
E
S
L
K
Q
E
L
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation