PhosphoNET

           
Protein Info 
   
Short Name:  MED19
Full Name:  Mediator of RNA polymerase II transcription subunit 19
Alias:  LCMR1; Lung cancer metastasis-related protein 1; Mediator complex subunit 19
Type:  Transcription protein
Mass (Da):  26273
Number AA:  244
UniProt ID:  A0JLT2
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016592     Uniprot OncoNet
Molecular Function:  GO:0016455     PhosphoSite+ KinaseNET
Biological Process:  GO:0006357  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T19ADPPPPPTALGFGPG
Site 2T42PAGGGPGTAPPPTAA
Site 3T47PGTAPPPTAATAPPG
Site 4T50APPPTAATAPPGADK
Site 5S58APPGADKSGAGCGPF
Site 6S74LMRELPGSTELTGST
Site 7T78LPGSTELTGSTNLIT
Site 8S80GSTELTGSTNLITHY
Site 9Y93HYNLEQAYNKFCGKK
Site 10S106KKVKEKLSNFLPDLP
Site 11S121GMIDLPGSHDNSSLR
Site 12S125LPGSHDNSSLRSLIE
Site 13S126PGSHDNSSLRSLIEK
Site 14S129HDNSSLRSLIEKPPI
Site 15S138IEKPPILSSSFNPIT
Site 16S139EKPPILSSSFNPITG
Site 17S140KPPILSSSFNPITGT
Site 18T156LAGFRLHTGPLPEQC
Site 19T184HKHKQSRTQDPVPPE
Site 20T192QDPVPPETPSDSDHK
Site 21S194PVPPETPSDSDHKKK
Site 22S196PPETPSDSDHKKKKK
Site 23S226KKKKNRHSPDHPGMG
Site 24S234PDHPGMGSSQASSSS
Site 25S235DHPGMGSSQASSSSS
Site 26S238GMGSSQASSSSSLR_
Site 27S239MGSSQASSSSSLR__
Site 28S240GSSQASSSSSLR___
Site 29S241SSQASSSSSLR____
Site 30S242SQASSSSSLR_____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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