PhosphoNET Kinase Predictor

Note - First set of Kinase Predictor V2 Scores are based on analysis of just the phosphosite independent of any other neighbouring phosphosites that might be recognized by the kinase shown. The maximum score possible is 1000. For the second set in the rightmost columns, the influence of the neighbouring phsophosites are also considered. These prediction scores are not scaled to a maximum of 1000.

Phosphosite
Human Protein:	SHH
Human P-Site:	S449
P-Site Sequence:	IGTWLLDSEALHPLG
UniProt:	Q15465
Intern. Prot. ID:

Protein Kinase Match	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score - Proximity
Kinase 1:	Trb3 (LOC57761)	Q96RU7	350	Trb3 (LOC57761)	Q96RU7	231
Kinase 2:	mTOR/FRAP	P42345	332	mTOR/FRAP	P42345	218
Kinase 3:	SgK307	Q8IWB6	314	SgK307	Q8IWB6	207
Kinase 4:	PKG2 (PRKG2)	Q13237	306	CDK4	P11802	203
Kinase 5:	STK33	Q9BYT3	305	COT (MAP3K8)	P41279	200
Kinase 6:	CDK4	P11802	305	PKG2 (PRKG2)	Q13237	199
Kinase 7:	COT (MAP3K8)	P41279	303	STK33	Q9BYT3	198
Kinase 8:	PLK1 (PLK)	P53350	296	MEK1 (MAP2K1)	Q02750	196
Kinase 9:	NIK (MAP3K14)	Q99558	293	PLK1 (PLK)	P53350	195
Kinase 10:	IKKa (CHUK)	O15111	292	MEK2 (MAP2K2)	P36507	195
Kinase 11:	OSR1	O95747	292	IKKa (CHUK)	O15111	194
Kinase 12:	RSK1 (RPS6KA2)	Q15418	291	IKKb (IKBKINASE)	O14920	192
Kinase 13:	RSK4 (RPS6KA6)	Q9UK32	291	PAK4	O96013	191
Kinase 14:	RSK3 (RPS6KA1)	Q15349	291	RSK1 (RPS6KA2)	Q15418	191
Kinase 15:	PAK4	O96013	291	OSR1	O95747	191
Kinase 16:	CK1a1 (CSNK1A1)	P48729	289	RSK4 (RPS6KA6)	Q9UK32	190
Kinase 17:	PEK (EIF2AK3)	Q9NZJ5	289	NIK (MAP3K14)	Q99558	190
Kinase 18:	IKKb (IKBKINASE)	O14920	288	VRK1	Q99986	190
Kinase 19:	CLK2	P49760	288	PLK2 (SNK)	Q9NYY3	190
Kinase 20:	VRK1	Q99986	287	RSK3 (RPS6KA1)	Q15349	189
Kinase 21:	PLK2 (SNK)	Q9NYY3	287	CK1a1 (CSNK1A1)	P48729	189
Kinase 22:	MAST1 (KIAA0973)	Q9Y2H9	284	CLK2	P49760	188
Kinase 23:	MEK1 (MAP2K1)	Q02750	284	PDK1 (PDPK1)	O15530	186
Kinase 24:	MEK2 (MAP2K2)	P36507	282	PEK (EIF2AK3)	Q9NZJ5	186
Kinase 25:	MAST2 (KIAA0807)	Q6P0Q8	282	PAK5	Q9P286	185
Kinase 26:	NEK10	Q6ZWH5	281	MAST1 (KIAA0973)	Q9Y2H9	184
Kinase 27:	PAK5	Q9P286	281	RSK2 (RPS6KA3)	P51812	184
Kinase 28:	RSK2 (RPS6KA3)	P51812	281	RSK4 (RPS6KA6)	Q9UK32	183
Kinase 29:	PDK1 (PDPK1)	O15530	280	RSK2 (RPS6KA3)	P51812	182
Kinase 30:	STLK3 (SPAK)	Q9UEW8	279	MAST2 (KIAA0807)	Q6P0Q8	182
Kinase 31:	MSK2 (RPS6KA4)	O75676	279	HSER (GUCY2C)	P25092	182
Kinase 32:	CLK4	Q9HAZ1	278	DMPK1 (DMPK)	Q09013	182
Kinase 33:	HSER (GUCY2C)	P25092	278	VRK2	Q86Y07	182
Kinase 34:	CLK3	P49761	278	STLK3 (SPAK)	Q9UEW8	182
Kinase 35:	MAST3 (KIAA0561)	O60307	278	CLK4	Q9HAZ1	182
Kinase 36:	DMPK1 (DMPK)	Q09013	278	MEK5 (MAP2K5)	Q13163	182
Kinase 37:	RSK4 (RPS6KA6)	Q9UK32	277	IRE2 (ERN2)	Q76MJ5	181
Kinase 38:	RSK2 (RPS6KA3)	P51812	277	MSK2 (RPS6KA4)	O75676	181
Kinase 39:	PSKH1 (HUMPSKB)	P11801	276	NEK10	Q6ZWH5	181
Kinase 40:	MYO3A	Q8NEV4	274	PSKH1 (HUMPSKB)	P11801	180
Kinase 41:	BARK1 (ADRBK1, GRK2)	P25098	274	MYO3A	Q8NEV4	180
Kinase 42:	MAST4 (KIAA0303)	O15021	273	CLK3	P49761	180
Kinase 43:	MEK5 (MAP2K5)	Q13163	273	ERK5 (MAPK7)	Q13164	179
Kinase 44:	IKKE	Q14164	273	RSK1 (RPS6KA2)	Q15418	179
Kinase 45:	VRK2	Q86Y07	272	MAST3 (KIAA0561)	O60307	179
Kinase 46:	CLK1	P49759	272	RSK3 (RPS6KA1)	Q15349	179
Kinase 47:	RSK1 (RPS6KA2)	Q15418	272	ZC2 (TNIK)	Q9UKE5	179
Kinase 48:	RSK3 (RPS6KA1)	Q15349	272	IKKE	Q14164	179
Kinase 49:	RIPK2	O43353	271	BARK1 (ADRBK1, GRK2)	P25098	178
Kinase 50:	p70S6K (RPS6KB1)	P23443	270	CLK1	P49759	178