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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP10
All Species:
21.52
Human Site:
Y236
Identified Species:
43.03
UniProt:
Q9Y6W6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6W6
NP_009138.1
482
52642
Y236
F
S
K
E
I
I
V
Y
D
E
N
T
N
E
P
Chimpanzee
Pan troglodytes
XP_001172978
482
52611
Y236
F
S
K
E
I
I
V
Y
D
E
N
T
N
E
P
Rhesus Macaque
Macaca mulatta
XP_001101558
482
52598
Y236
F
S
K
E
I
I
V
Y
D
E
N
T
N
E
P
Dog
Lupus familis
XP_849569
487
52932
Y236
F
S
K
E
I
I
V
Y
D
E
N
T
N
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESS0
483
52512
Y237
F
S
K
E
I
I
V
Y
D
E
N
T
N
E
P
Rat
Rattus norvegicus
Q64346
381
42300
S159
D
G
S
C
S
S
S
S
P
P
L
P
V
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512790
480
52472
N236
E
I
V
V
Y
D
E
N
T
N
E
P
N
R
V
Chicken
Gallus gallus
NP_001026215
478
51814
N236
I
V
Y
D
E
N
T
N
E
P
S
R
V
M
P
Frog
Xenopus laevis
NP_001083256
378
42018
S156
N
L
D
S
S
C
S
S
S
S
P
P
V
L
G
Zebra Danio
Brachydanio rerio
XP_001919447
210
23610
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392375
608
66068
Y339
H
Y
R
E
V
V
V
Y
D
D
C
T
D
D
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789413
532
58126
V253
L
D
Q
D
K
E
V
V
V
Y
D
E
E
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
95.2
N.A.
96
27.7
N.A.
91
88.3
27.5
35.6
N.A.
N.A.
31.7
N.A.
31
Protein Similarity:
100
99.7
99.3
96.9
N.A.
97.7
43.9
N.A.
94.6
91.2
43.5
40
N.A.
N.A.
49.6
N.A.
50.9
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
6.6
6.6
0
0
N.A.
N.A.
33.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
6.6
26.6
0
0
N.A.
N.A.
73.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
0
9
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
9
9
17
0
9
0
0
50
9
9
0
9
9
0
% D
% Glu:
9
0
0
50
9
9
9
0
9
42
9
9
9
42
0
% E
% Phe:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
17
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
42
42
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
42
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
0
0
0
0
0
0
0
0
9
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
0
9
0
17
0
9
42
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
17
9
25
0
0
50
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
9
0
9
0
% R
% Ser:
0
42
9
9
17
9
17
17
9
9
9
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
0
9
0
0
50
0
0
0
% T
% Val:
0
9
9
9
9
9
59
9
9
0
0
0
25
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
9
0
0
50
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _