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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP10
All Species:
31.21
Human Site:
S378
Identified Species:
62.42
UniProt:
Q9Y6W6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6W6
NP_009138.1
482
52642
S378
K
R
L
P
A
T
D
S
N
K
Q
N
L
R
Q
Chimpanzee
Pan troglodytes
XP_001172978
482
52611
S378
K
R
L
P
A
T
D
S
N
K
Q
N
L
R
Q
Rhesus Macaque
Macaca mulatta
XP_001101558
482
52598
S378
K
R
L
P
A
T
D
S
N
K
Q
N
L
R
Q
Dog
Lupus familis
XP_849569
487
52932
S378
K
R
L
P
A
T
D
S
N
K
Q
N
L
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESS0
483
52512
S379
K
R
L
P
A
T
D
S
N
K
Q
N
L
R
R
Rat
Rattus norvegicus
Q64346
381
42300
G296
V
L
V
H
C
L
A
G
I
S
R
S
V
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512790
480
52472
S376
K
R
L
P
A
T
D
S
N
K
Q
N
L
R
Q
Chicken
Gallus gallus
NP_001026215
478
51814
S374
K
R
L
P
A
T
D
S
N
K
Q
N
L
R
Q
Frog
Xenopus laevis
NP_001083256
378
42018
G293
V
L
V
H
C
L
A
G
I
S
R
S
V
T
V
Zebra Danio
Brachydanio rerio
XP_001919447
210
23610
A125
A
F
E
F
I
E
E
A
H
Q
A
G
R
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392375
608
66068
S488
R
Q
I
P
A
S
D
S
G
H
Q
N
L
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789413
532
58126
N405
M
R
I
P
V
R
D
N
G
L
I
N
L
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
95.2
N.A.
96
27.7
N.A.
91
88.3
27.5
35.6
N.A.
N.A.
31.7
N.A.
31
Protein Similarity:
100
99.7
99.3
96.9
N.A.
97.7
43.9
N.A.
94.6
91.2
43.5
40
N.A.
N.A.
49.6
N.A.
50.9
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
100
100
0
0
N.A.
N.A.
53.3
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
100
26.6
26.6
N.A.
N.A.
86.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
67
0
17
9
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
9
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
17
17
0
0
9
0
9
0
% G
% His:
0
0
0
17
0
0
0
0
9
9
0
0
0
0
0
% H
% Ile:
0
0
17
0
9
0
0
0
17
0
9
0
0
0
0
% I
% Lys:
59
0
0
0
0
0
0
0
0
59
0
0
0
9
0
% K
% Leu:
0
17
59
0
0
17
0
0
0
9
0
0
75
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
9
59
0
0
75
0
0
0
% N
% Pro:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
9
67
0
0
0
59
% Q
% Arg:
9
67
0
0
0
9
0
0
0
0
17
0
9
67
9
% R
% Ser:
0
0
0
0
0
9
0
67
0
17
0
17
0
0
0
% S
% Thr:
0
0
0
0
0
59
0
0
0
0
0
0
0
17
0
% T
% Val:
17
0
17
0
9
0
0
0
0
0
0
0
17
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _