KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP10
All Species:
22.42
Human Site:
S169
Identified Species:
44.85
UniProt:
Q9Y6W6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6W6
NP_009138.1
482
52642
S169
C
S
K
S
H
L
P
S
Q
G
P
V
I
I
D
Chimpanzee
Pan troglodytes
XP_001172978
482
52611
S169
C
S
K
S
H
L
P
S
Q
G
P
V
I
I
D
Rhesus Macaque
Macaca mulatta
XP_001101558
482
52598
S169
C
N
K
S
H
L
P
S
Q
G
P
V
I
I
D
Dog
Lupus familis
XP_849569
487
52932
S169
C
S
K
S
P
L
P
S
Q
G
P
V
I
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESS0
483
52512
S170
C
S
K
S
H
L
P
S
Q
G
P
V
I
I
D
Rat
Rattus norvegicus
Q64346
381
42300
T92
R
F
T
R
R
C
G
T
D
T
V
V
L
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512790
480
52472
P169
G
H
Q
P
S
Q
G
P
V
I
I
D
C
R
P
Chicken
Gallus gallus
NP_001026215
478
51814
I169
A
Q
N
Q
G
P
V
I
I
D
C
R
P
F
M
Frog
Xenopus laevis
NP_001083256
378
42018
C89
R
D
K
F
A
R
R
C
G
T
D
T
V
V
L
Zebra Danio
Brachydanio rerio
XP_001919447
210
23610
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392375
608
66068
S272
R
S
S
P
R
E
G
S
A
S
S
V
V
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789413
532
58126
S186
S
R
L
C
R
P
R
S
G
S
V
I
L
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
95.2
N.A.
96
27.7
N.A.
91
88.3
27.5
35.6
N.A.
N.A.
31.7
N.A.
31
Protein Similarity:
100
99.7
99.3
96.9
N.A.
97.7
43.9
N.A.
94.6
91.2
43.5
40
N.A.
N.A.
49.6
N.A.
50.9
P-Site Identity:
100
100
93.3
93.3
N.A.
100
13.3
N.A.
0
0
6.6
0
N.A.
N.A.
26.6
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
26.6
N.A.
6.6
0
20
0
N.A.
N.A.
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
42
0
0
9
0
9
0
9
0
0
9
0
9
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
9
9
9
0
0
67
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
0
0
9
0
25
0
17
42
0
0
0
0
0
% G
% His:
0
9
0
0
34
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
9
9
9
9
42
42
0
% I
% Lys:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
42
0
0
0
0
0
0
17
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
17
9
17
42
9
0
0
42
0
9
0
9
% P
% Gln:
0
9
9
9
0
9
0
0
42
0
0
0
0
0
0
% Q
% Arg:
25
9
0
9
25
9
17
0
0
0
0
9
0
9
0
% R
% Ser:
9
42
9
42
9
0
0
59
0
17
9
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
9
0
17
0
9
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
9
0
17
59
17
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _