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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX49
All Species:
26.97
Human Site:
Y223
Identified Species:
45.64
UniProt:
Q9Y6V7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6V7
NP_061943.2
483
54226
Y223
V
E
Q
L
D
Q
R
Y
L
L
V
P
E
K
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115617
527
58467
Y223
V
E
Q
L
D
Q
R
Y
L
L
V
P
E
K
V
Dog
Lupus familis
XP_541930
488
54668
Y223
V
E
Q
L
D
Q
R
Y
L
L
V
P
E
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q4FZF3
480
54076
Y223
V
E
Q
L
D
Q
R
Y
L
L
V
P
E
K
V
Rat
Rattus norvegicus
NP_001108495
480
54257
Y223
V
E
Q
L
D
Q
R
Y
L
L
V
P
E
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026109
402
45009
L199
T
L
N
E
L
K
S
L
A
M
N
R
P
F
F
Frog
Xenopus laevis
NP_001085167
448
50232
L233
K
Y
Q
T
V
E
K
L
Q
Q
F
Y
V
F
I
Zebra Danio
Brachydanio rerio
NP_938179
468
53112
F223
V
E
E
L
D
Q
R
F
I
L
T
P
E
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07886
521
59659
Y226
V
E
T
L
D
Q
R
Y
L
L
C
A
D
Y
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34580
489
54209
L258
R
Y
K
T
V
D
N
L
K
Q
H
Y
I
F
V
Sea Urchin
Strong. purpuratus
XP_781784
301
33445
T101
D
H
I
K
S
T
S
T
F
D
L
H
A
I
K
Poplar Tree
Populus trichocarpa
XP_002311293
496
55653
Y281
V
D
T
L
N
Q
Q
Y
I
Q
M
P
K
N
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SA27
491
54817
F278
V
D
T
L
T
Q
Q
F
I
F
E
D
K
D
A
Baker's Yeast
Sacchar. cerevisiae
P38719
431
47860
S225
V
D
N
V
A
I
P
S
T
L
K
I
E
Y
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
84.8
94
N.A.
89.8
89
N.A.
N.A.
70.3
44.7
73.5
N.A.
45.4
N.A.
42.7
40.9
Protein Similarity:
100
N.A.
86.3
95.9
N.A.
94
94
N.A.
N.A.
76.4
59.8
87.1
N.A.
63.9
N.A.
59.7
52.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
0
6.6
73.3
N.A.
60
N.A.
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
13.3
26.6
93.3
N.A.
66.6
N.A.
13.3
6.6
Percent
Protein Identity:
42.5
N.A.
N.A.
43.3
43.4
N.A.
Protein Similarity:
62.3
N.A.
N.A.
62.9
59.8
N.A.
P-Site Identity:
40
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
80
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
22
0
0
50
8
0
0
0
8
0
8
8
8
8
% D
% Glu:
0
50
8
8
0
8
0
0
0
0
8
0
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
8
8
8
0
0
22
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
22
0
0
8
8
8
15
% I
% Lys:
8
0
8
8
0
8
8
0
8
0
8
0
15
43
8
% K
% Leu:
0
8
0
65
8
0
0
22
43
58
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
0
0
15
0
8
0
8
0
0
0
8
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
50
8
0
0
% P
% Gln:
0
0
43
0
0
65
15
0
8
22
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
50
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
8
0
15
8
0
0
0
0
0
0
0
% S
% Thr:
8
0
22
15
8
8
0
8
8
0
8
0
0
0
0
% T
% Val:
72
0
0
8
15
0
0
0
0
0
36
0
8
0
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
50
0
0
0
15
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _