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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX49 All Species: 6.06
Human Site: T468 Identified Species: 10.26
UniProt: Q9Y6V7 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6V7 NP_061943.2 483 54226 T468 H K G R P P R T P S G S H S G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115617 527 58467 T511 K N M A E V V T P T K G H P L
Dog Lupus familis XP_541930 488 54668 A473 P G G R P P R A P P E A H S A
Cat Felis silvestris
Mouse Mus musculus Q4FZF3 480 54076 P465 S T V R R S R P P R S R P Q E
Rat Rattus norvegicus NP_001108495 480 54257 P465 S T G R R S R P P R P R P Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026109 402 45009 L385 E K L V L D I L T H V N V T R
Frog Xenopus laevis NP_001085167 448 50232 V433 D K E G S L G V R K K V T G G
Zebra Danio Brachydanio rerio NP_938179 468 53112 S450 L K G K N P Q S K K E K K K H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07886 521 59659 T490 G K G R S R A T Q E D T P T K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34580 489 54209 G474 I K S M G G R G G S G G G R G
Sea Urchin Strong. purpuratus XP_781784 301 33445 P287 N H N V P T S P K D Y I H R V
Poplar Tree Populus trichocarpa XP_002311293 496 55653 G480 Q K S L A E K G L L K N K R R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SA27 491 54817 T472 R R K L K R K T L A D K G L L
Baker's Yeast Sacchar. cerevisiae P38719 431 47860 R417 E N F G E R K R Q Q K K K Q N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 84.8 94 N.A. 89.8 89 N.A. N.A. 70.3 44.7 73.5 N.A. 45.4 N.A. 42.7 40.9
Protein Similarity: 100 N.A. 86.3 95.9 N.A. 94 94 N.A. N.A. 76.4 59.8 87.1 N.A. 63.9 N.A. 59.7 52.8
P-Site Identity: 100 N.A. 20 53.3 N.A. 20 26.6 N.A. N.A. 6.6 13.3 20 N.A. 26.6 N.A. 33.3 13.3
P-Site Similarity: 100 N.A. 26.6 60 N.A. 20 26.6 N.A. N.A. 20 13.3 40 N.A. 40 N.A. 33.3 20
Percent
Protein Identity: 42.5 N.A. N.A. 43.3 43.4 N.A.
Protein Similarity: 62.3 N.A. N.A. 62.9 59.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 20 N.A. N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 8 8 0 8 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 0 0 0 8 15 0 0 0 0 % D
% Glu: 15 0 8 0 15 8 0 0 0 8 15 0 0 0 15 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 36 15 8 8 8 15 8 0 15 15 15 8 22 % G
% His: 8 8 0 0 0 0 0 0 0 8 0 0 29 0 8 % H
% Ile: 8 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % I
% Lys: 8 50 8 8 8 0 22 0 15 15 29 22 22 8 8 % K
% Leu: 8 0 8 15 8 8 0 8 15 8 0 0 0 8 15 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 15 8 0 8 0 0 0 0 0 0 15 0 0 8 % N
% Pro: 8 0 0 0 22 22 0 22 36 8 8 0 22 8 0 % P
% Gln: 8 0 0 0 0 0 8 0 15 8 0 0 0 22 0 % Q
% Arg: 8 8 0 36 15 22 36 8 8 15 0 15 0 22 15 % R
% Ser: 15 0 15 0 15 15 8 8 0 15 8 8 0 15 0 % S
% Thr: 0 15 0 0 0 8 0 29 8 8 0 8 8 15 0 % T
% Val: 0 0 8 15 0 8 8 8 0 0 8 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _