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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX49 All Species: 4.55
Human Site: S474 Identified Species: 7.69
UniProt: Q9Y6V7 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6V7 NP_061943.2 483 54226 S474 R T P S G S H S G P V P S Q G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115617 527 58467 P517 V T P T K G H P L E V P H T G
Dog Lupus familis XP_541930 488 54668 S479 R A P P E A H S A P A P I H G
Cat Felis silvestris
Mouse Mus musculus Q4FZF3 480 54076 Q471 R P P R S R P Q E P A Q A E A
Rat Rattus norvegicus NP_001108495 480 54257 Q471 R P P R P R P Q E P A R A E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026109 402 45009 T391 I L T H V N V T R R E C E I V
Frog Xenopus laevis NP_001085167 448 50232 G439 G V R K K V T G G K F K K K K
Zebra Danio Brachydanio rerio NP_938179 468 53112 K456 Q S K K E K K K H E K S A K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07886 521 59659 T496 A T Q E D T P T K P L K R L N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34580 489 54209 R480 R G G S G G G R G G K K K K M
Sea Urchin Strong. purpuratus XP_781784 301 33445 R293 S P K D Y I H R V G R T A R A
Poplar Tree Populus trichocarpa XP_002311293 496 55653 R486 K G L L K N K R R K R K S K D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SA27 491 54817 L478 K T L A D K G L L K K R G K R
Baker's Yeast Sacchar. cerevisiae P38719 431 47860 Q423 K R Q Q K K K Q N D G K S L R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 84.8 94 N.A. 89.8 89 N.A. N.A. 70.3 44.7 73.5 N.A. 45.4 N.A. 42.7 40.9
Protein Similarity: 100 N.A. 86.3 95.9 N.A. 94 94 N.A. N.A. 76.4 59.8 87.1 N.A. 63.9 N.A. 59.7 52.8
P-Site Identity: 100 N.A. 40 46.6 N.A. 20 20 N.A. N.A. 0 6.6 0 N.A. 13.3 N.A. 26.6 6.6
P-Site Similarity: 100 N.A. 46.6 53.3 N.A. 33.3 33.3 N.A. N.A. 13.3 13.3 26.6 N.A. 33.3 N.A. 33.3 20
Percent
Protein Identity: 42.5 N.A. N.A. 43.3 43.4 N.A.
Protein Similarity: 62.3 N.A. N.A. 62.9 59.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 8 0 0 8 0 22 0 29 0 29 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 8 15 0 0 0 0 8 0 0 0 0 8 % D
% Glu: 0 0 0 8 15 0 0 0 15 15 8 0 8 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 15 8 0 15 15 15 8 22 15 8 0 8 0 22 % G
% His: 0 0 0 8 0 0 29 0 8 0 0 0 8 8 0 % H
% Ile: 8 0 0 0 0 8 0 0 0 0 0 0 8 8 0 % I
% Lys: 22 0 15 15 29 22 22 8 8 22 22 36 15 36 8 % K
% Leu: 0 8 15 8 0 0 0 8 15 0 8 0 0 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 15 0 0 8 0 0 0 0 0 8 % N
% Pro: 0 22 36 8 8 0 22 8 0 36 0 22 0 0 0 % P
% Gln: 8 0 15 8 0 0 0 22 0 0 0 8 0 8 0 % Q
% Arg: 36 8 8 15 0 15 0 22 15 8 15 15 8 8 15 % R
% Ser: 8 8 0 15 8 8 0 15 0 0 0 8 22 0 0 % S
% Thr: 0 29 8 8 0 8 8 15 0 0 0 8 0 8 0 % T
% Val: 8 8 0 0 8 8 8 0 8 0 15 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _