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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX49
All Species:
1.52
Human Site:
S472
Identified Species:
2.56
UniProt:
Q9Y6V7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6V7
NP_061943.2
483
54226
S472
P
P
R
T
P
S
G
S
H
S
G
P
V
P
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115617
527
58467
G515
E
V
V
T
P
T
K
G
H
P
L
E
V
P
H
Dog
Lupus familis
XP_541930
488
54668
A477
P
P
R
A
P
P
E
A
H
S
A
P
A
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q4FZF3
480
54076
R469
R
S
R
P
P
R
S
R
P
Q
E
P
A
Q
A
Rat
Rattus norvegicus
NP_001108495
480
54257
R469
R
S
R
P
P
R
P
R
P
Q
E
P
A
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026109
402
45009
N389
L
D
I
L
T
H
V
N
V
T
R
R
E
C
E
Frog
Xenopus laevis
NP_001085167
448
50232
V437
S
L
G
V
R
K
K
V
T
G
G
K
F
K
K
Zebra Danio
Brachydanio rerio
NP_938179
468
53112
K454
N
P
Q
S
K
K
E
K
K
K
H
E
K
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07886
521
59659
T494
S
R
A
T
Q
E
D
T
P
T
K
P
L
K
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34580
489
54209
G478
G
G
R
G
G
S
G
G
G
R
G
G
K
K
K
Sea Urchin
Strong. purpuratus
XP_781784
301
33445
I291
P
T
S
P
K
D
Y
I
H
R
V
G
R
T
A
Poplar Tree
Populus trichocarpa
XP_002311293
496
55653
N484
A
E
K
G
L
L
K
N
K
R
R
K
R
K
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SA27
491
54817
K476
K
R
K
T
L
A
D
K
G
L
L
K
K
R
G
Baker's Yeast
Sacchar. cerevisiae
P38719
431
47860
K421
E
R
K
R
Q
Q
K
K
K
Q
N
D
G
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
84.8
94
N.A.
89.8
89
N.A.
N.A.
70.3
44.7
73.5
N.A.
45.4
N.A.
42.7
40.9
Protein Similarity:
100
N.A.
86.3
95.9
N.A.
94
94
N.A.
N.A.
76.4
59.8
87.1
N.A.
63.9
N.A.
59.7
52.8
P-Site Identity:
100
N.A.
33.3
53.3
N.A.
20
20
N.A.
N.A.
0
6.6
6.6
N.A.
13.3
N.A.
26.6
13.3
P-Site Similarity:
100
N.A.
40
60
N.A.
26.6
26.6
N.A.
N.A.
13.3
6.6
26.6
N.A.
33.3
N.A.
26.6
20
Percent
Protein Identity:
42.5
N.A.
N.A.
43.3
43.4
N.A.
Protein Similarity:
62.3
N.A.
N.A.
62.9
59.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
8
0
8
0
0
8
0
22
0
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
0
8
15
0
0
0
0
8
0
0
0
% D
% Glu:
15
8
0
0
0
8
15
0
0
0
15
15
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
8
8
15
8
0
15
15
15
8
22
15
8
0
8
% G
% His:
0
0
0
0
0
8
0
0
29
0
8
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% I
% Lys:
8
0
22
0
15
15
29
22
22
8
8
22
22
36
15
% K
% Leu:
8
8
0
8
15
8
0
0
0
8
15
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
15
0
0
8
0
0
0
0
% N
% Pro:
22
22
0
22
36
8
8
0
22
8
0
36
0
22
0
% P
% Gln:
0
0
8
0
15
8
0
0
0
22
0
0
0
8
0
% Q
% Arg:
15
22
36
8
8
15
0
15
0
22
15
8
15
15
8
% R
% Ser:
15
15
8
8
0
15
8
8
0
15
0
0
0
8
22
% S
% Thr:
0
8
0
29
8
8
0
8
8
15
0
0
0
8
0
% T
% Val:
0
8
8
8
0
0
8
8
8
0
8
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _