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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKB
All Species:
26.36
Human Site:
Y298
Identified Species:
58
UniProt:
Q9Y6T7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6T7
NP_004071.1
804
90595
Y298
P
P
S
C
I
K
T
Y
V
K
S
K
R
N
T
Chimpanzee
Pan troglodytes
XP_001148960
804
90603
Y298
P
P
S
C
I
K
T
Y
V
K
S
K
R
N
T
Rhesus Macaque
Macaca mulatta
XP_001105384
789
88608
Y283
P
P
S
C
I
K
T
Y
V
K
S
K
K
N
A
Dog
Lupus familis
XP_539445
886
99592
Y380
P
P
S
C
I
K
T
Y
V
K
S
K
K
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6NS52
802
90253
Y297
P
P
S
C
I
K
T
Y
V
K
S
K
K
N
T
Rat
Rattus norvegicus
P49621
801
90269
Y296
P
P
S
C
I
K
T
Y
V
K
S
K
K
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
Q239
H
K
T
V
K
C
Y
Q
G
L
T
G
L
H
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
K438
S
C
I
T
T
Y
V
K
S
K
K
P
K
C
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
N315
C
V
R
S
A
A
T
N
C
I
R
T
Y
S
S
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
Y727
P
A
C
C
I
S
T
Y
V
K
S
K
R
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
T270
K
Y
K
Q
T
N
E
T
S
A
D
T
G
N
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.6
88.2
N.A.
96.5
96.1
N.A.
72.2
N.A.
N.A.
N.A.
N.A.
34.9
N.A.
52
42.4
Protein Similarity:
100
99.8
97.5
89.5
N.A.
98.1
97.8
N.A.
78.2
N.A.
N.A.
N.A.
N.A.
47.5
N.A.
66.1
52.6
P-Site Identity:
100
100
86.6
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
6.6
73.3
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
10
0
0
0
10
0
0
0
0
10
% A
% Cys:
10
10
10
64
0
10
0
0
10
0
0
0
0
10
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
0
64
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
10
10
0
10
55
0
10
0
73
10
64
46
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
0
0
0
64
0
% N
% Pro:
64
55
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
10
0
28
0
0
% R
% Ser:
10
0
55
10
0
10
0
0
19
0
64
0
0
10
19
% S
% Thr:
0
0
10
10
19
0
73
10
0
0
10
19
0
10
55
% T
% Val:
0
10
0
10
0
0
10
0
64
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
10
64
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _