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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKB
All Species:
14.24
Human Site:
T122
Identified Species:
31.33
UniProt:
Q9Y6T7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6T7
NP_004071.1
804
90595
T122
A
I
T
P
P
R
T
T
S
P
A
N
T
C
S
Chimpanzee
Pan troglodytes
XP_001148960
804
90603
T122
A
I
T
P
P
R
T
T
S
P
A
N
T
C
S
Rhesus Macaque
Macaca mulatta
XP_001105384
789
88608
H119
S
S
S
P
E
V
I
H
L
K
D
I
V
C
Y
Dog
Lupus familis
XP_539445
886
99592
S205
A
I
T
P
P
R
T
S
P
A
N
T
C
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6NS52
802
90253
S122
A
I
T
P
P
R
S
S
P
A
N
T
C
S
P
Rat
Rattus norvegicus
P49621
801
90269
S122
A
I
T
P
P
R
S
S
P
A
N
T
C
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
S86
S
E
L
E
N
I
I
S
Q
M
M
H
V
A
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
K259
D
I
K
L
L
A
R
K
L
S
H
F
D
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
E127
T
D
R
S
Q
S
S
E
P
Q
A
L
V
C
I
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
S551
A
L
A
A
S
R
G
S
L
A
H
P
D
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
R117
A
S
E
S
F
F
H
R
C
T
I
C
G
A
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.6
88.2
N.A.
96.5
96.1
N.A.
72.2
N.A.
N.A.
N.A.
N.A.
34.9
N.A.
52
42.4
Protein Similarity:
100
99.8
97.5
89.5
N.A.
98.1
97.8
N.A.
78.2
N.A.
N.A.
N.A.
N.A.
47.5
N.A.
66.1
52.6
P-Site Identity:
100
100
13.3
46.6
N.A.
40
40
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
26.6
53.3
N.A.
53.3
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
0
10
10
0
10
0
0
0
37
28
0
0
19
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
10
28
37
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
0
10
0
19
0
0
% D
% Glu:
0
10
10
10
10
0
0
10
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
10
10
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
19
10
0
0
0
% H
% Ile:
0
55
0
0
0
10
19
0
0
0
10
10
0
0
10
% I
% Lys:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% K
% Leu:
0
10
10
10
10
0
0
0
28
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
28
19
0
0
0
% N
% Pro:
0
0
0
55
46
0
0
0
37
19
0
10
0
10
28
% P
% Gln:
0
0
0
0
10
0
0
0
10
10
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
55
10
10
0
0
0
0
0
0
0
% R
% Ser:
19
19
10
19
10
10
28
46
19
10
0
0
0
19
19
% S
% Thr:
10
0
46
0
0
0
28
19
0
10
0
28
19
0
10
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
28
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _